DHX29 (DExH-box helicase 29)

2007-04-01  

Identity

HGNC
DHX29
LOCATION
5q11.2
LOCUSID
54505
ALIAS
DDX29
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54505
MIM: 612720
HGNC: 15815
Ensembl: ENSG00000067248

Variants:

dbSNP: 54505
ClinVar: 54505
TCGA: ENSG00000067248
COSMIC: DHX29

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067248ENST00000251636Q7Z478
ENSG00000067248ENST00000508346H0Y8L1
ENSG00000067248ENST00000621106A0A087WYN9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
191098952008Translation initiation on mammalian mRNAs with structured 5'UTRs requires DExH-box protein DHX29.109
200187252009The helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesis.47
230476962012Roles of individual domains in the function of DHX29, an essential factor required for translation of structured mammalian mRNAs.21
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
248217822014Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in the human airway system.16
294621852018DHX29 functions as an RNA co-sensor for MDA5-mediated EMCV-specific antiviral immunity.9
270675422016DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context.8
277336512016DHX29 and eIF3 cooperate in ribosomal scanning on structured mRNAs during translation initiation.7

Citation

Dessen P

DHX29 (DExH-box helicase 29)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46773/dhx29