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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

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DHX33 (DEAH (Asp-Glu-Ala-His) box polypeptide 33)


Other namesDDX33
HGNC (Hugo) DHX33
LocusID (NCBI) 56919
Location 17p13.2
Location_base_pair Starts at 5344232 and ends at 5372380 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)DHX33   16718
Entrez_Gene (NCBI)DHX33  56919  DEAH (Asp-Glu-Ala-His) box polypeptide 33
GeneCards (Weizmann)DHX33
Ensembl hg19 (Hinxton)ENSG00000005100 [Gene_View]  chr17:5344232-5372380 [Contig_View]  DHX33 [Vega]
Ensembl hg38 (Hinxton)ENSG00000005100 [Gene_View]  chr17:5344232-5372380 [Contig_View]  DHX33 [Vega]
ICGC DataPortalENSG00000005100
AceView (NCBI)DHX33
Genatlas (Paris)DHX33
SOURCE (Princeton)DHX33
Genomic and cartography
GoldenPath hg19 (UCSC)DHX33  -     chr17:5344232-5372380 -  17p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DHX33  -     17p13.2   [Description]    (hg38-Dec_2013)
EnsemblDHX33 - 17p13.2 [CytoView hg19]  DHX33 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIDHX33 [Mapview hg19]  DHX33 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK025625 AK026944 AK295074 AK295760 AK314580
RefSeq transcript (Entrez)NM_001199699 NM_020162
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010718 NW_001838403 NW_004929405
Consensus coding sequences : CCDS (NCBI)DHX33
Cluster EST : UnigeneHs.250456 [ NCBI ]
CGAP (NCI)Hs.250456
Alternative Splicing : Fast-db (Paris)GSHG0013025
Alternative Splicing GalleryENSG00000005100
Gene ExpressionDHX33 [ NCBI-GEO ]     DHX33 [ SEEK ]   DHX33 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6R0 (Uniprot)
NextProtQ9H6R0  [Medical]
With graphics : InterProQ9H6R0
Splice isoforms : SwissVarQ9H6R0 (Swissvar)
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ] [ IntEnz-EBI ] [ BRENDA ] [ KEGG ]   
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DNA/RNA_helicase_DEAD/DEAH_N    DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Related proteins : CluSTrQ9H6R0
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
DMDM Disease mutations56919
Blocks (Seattle)Q9H6R0
Human Protein AtlasENSG00000005100
Peptide AtlasQ9H6R0
IPIIPI00655950   IPI00302860   IPI00789223   
Protein Interaction databases
IntAct (EBI)Q9H6R0
Ontologies - Pathways
Ontology : AmiGOrDNA binding  ATP binding  nucleoplasm  nucleolus  ATP catabolic process  ATP-dependent helicase activity  activating transcription factor binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase I promoter  
Ontology : EGO-EBIrDNA binding  ATP binding  nucleoplasm  nucleolus  ATP catabolic process  ATP-dependent helicase activity  activating transcription factor binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase I promoter  
Protein Interaction DatabaseDHX33
DoCM (Curated mutations)DHX33
Wikipedia pathwaysDHX33
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerDHX33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX33
Exome Variant ServerDHX33
SNP (GeneSNP Utah)DHX33
Genetic variants : HAPMAPDHX33
Genomic Variants (DGV)DHX33 [DGVbeta]
ICGC Data PortalENSG00000005100 
Somatic Mutations in Cancer : COSMICDHX33 
CONAN: Copy Number AnalysisDHX33 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)17:5344232-5372380
Mutations and Diseases : HGMDDHX33
NextProtQ9H6R0 [Medical]
Disease Genetic AssociationDHX33
Huge Navigator DHX33 [HugePedia]  DHX33 [HugeCancerGEM]
snp3D : Map Gene to Disease56919
DGIdb (Drug Gene Interaction db)DHX33
General knowledge
Homologs : HomoloGeneDHX33
Homology/Alignments : Family Browser (UCSC)DHX33
Phylogenetic Trees/Animal Genes : TreeFamDHX33
Chemical/Protein Interactions : CTD56919
Chemical/Pharm GKB GenePA27220
Clinical trialDHX33
Cancer Resource (Charite)ENSG00000005100
Other databases
PubMed19 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 15:28:08 CET 2015

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