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DHX33 (DEAH-box helicase 33)

Identity

Other namesDDX33
HGNC (Hugo) DHX33
LocusID (NCBI) 56919
Atlas_Id 47060
Location 17p13.2
Location_base_pair Starts at 5344232 and ends at 5372380 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATP5J2-PTCD1 (7q22.1) / DHX33 (17p13.2)CUL4B (Xq24) / DHX33 (17p13.2)SMG6 (17p13.3) / DHX33 (17p13.2)
SMG6 17p13.3 / DHX33 17p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX33   16718
Cards
Entrez_Gene (NCBI)DHX33  56919  DEAH-box helicase 33
GeneCards (Weizmann)DHX33
Ensembl hg19 (Hinxton)ENSG00000005100 [Gene_View]  chr17:5344232-5372380 [Contig_View]  DHX33 [Vega]
Ensembl hg38 (Hinxton)ENSG00000005100 [Gene_View]  chr17:5344232-5372380 [Contig_View]  DHX33 [Vega]
ICGC DataPortalENSG00000005100
TCGA cBioPortalDHX33
AceView (NCBI)DHX33
Genatlas (Paris)DHX33
WikiGenes56919
SOURCE (Princeton)DHX33
Genomic and cartography
GoldenPath hg19 (UCSC)DHX33  -     chr17:5344232-5372380 -  17p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DHX33  -     17p13.2   [Description]    (hg38-Dec_2013)
EnsemblDHX33 - 17p13.2 [CytoView hg19]  DHX33 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIDHX33 [Mapview hg19]  DHX33 [Mapview hg38]
OMIM614405   
Gene and transcription
Genbank (Entrez)AK025625 AK026944 AK295074 AK295760 AK314580
RefSeq transcript (Entrez)NM_001199699 NM_020162
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)DHX33
Cluster EST : UnigeneHs.250456 [ NCBI ]
CGAP (NCI)Hs.250456
Alternative Splicing GalleryENSG00000005100
Gene ExpressionDHX33 [ NCBI-GEO ]   DHX33 [ EBI - ARRAY_EXPRESS ]   DHX33 [ SEEK ]   DHX33 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56919
GTEX Portal (Tissue expression)DHX33
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6R0 (Uniprot)
NextProtQ9H6R0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H6R0
Splice isoforms : SwissVarQ9H6R0 (Swissvar)
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9H6R0
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
DMDM Disease mutations56919
Blocks (Seattle)DHX33
SuperfamilyQ9H6R0
Human Protein AtlasENSG00000005100
Peptide AtlasQ9H6R0
HPRD13143
IPIIPI00655950   IPI00302860   IPI00789223   
Protein Interaction databases
DIP (DOE-UCLA)Q9H6R0
IntAct (EBI)Q9H6R0
FunCoupENSG00000005100
BioGRIDDHX33
STRING (EMBL)DHX33
ZODIACDHX33
Ontologies - Pathways
QuickGOQ9H6R0
Ontology : AmiGOrDNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  nucleolus  cytoplasm  RNA processing  activating transcription factor binding  poly(A) RNA binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase I promoter  
Ontology : EGO-EBIrDNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  nucleolus  cytoplasm  RNA processing  activating transcription factor binding  poly(A) RNA binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase I promoter  
NDEx Network
Atlas of Cancer Signalling NetworkDHX33
Wikipedia pathwaysDHX33
Orthology - Evolution
OrthoDB56919
GeneTree (enSembl)ENSG00000005100
Phylogenetic Trees/Animal Genes : TreeFamDHX33
Homologs : HomoloGeneDHX33
Homology/Alignments : Family Browser (UCSC)DHX33
Gene fusions - Rearrangements
Fusion: TCGASMG6 17p13.3 DHX33 17p13.2 PRAD
Polymorphisms : SNP, variants
NCBI Variation ViewerDHX33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX33
dbVarDHX33
ClinVarDHX33
1000_GenomesDHX33 
Exome Variant ServerDHX33
ExAC (Exome Aggregation Consortium)DHX33 (select the gene name)
Genetic variants : HAPMAP56919
Genomic Variants (DGV)DHX33 [DGVbeta]
Mutations
ICGC Data PortalDHX33 
TCGA Data PortalDHX33 
Broad Tumor PortalDHX33
OASIS PortalDHX33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX33 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX33
DgiDB (Drug Gene Interaction Database)DHX33
DoCM (Curated mutations)DHX33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX33 (select a term)
intoGenDHX33
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)17:5344232-5372380  ENSG00000005100
CONAN: Copy Number AnalysisDHX33 
Mutations and Diseases : HGMDDHX33
OMIM614405   
MedgenDHX33
Genetic Testing Registry DHX33
NextProtQ9H6R0 [Medical]
TSGene56919
GENETestsDHX33
Huge Navigator DHX33 [HugePedia]
snp3D : Map Gene to Disease56919
BioCentury BCIQDHX33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56919
Chemical/Pharm GKB GenePA27220
Clinical trialDHX33
Miscellaneous
canSAR (ICR)DHX33 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX33
EVEXDHX33
GoPubMedDHX33
iHOPDHX33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:43:48 CEST 2016

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