Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DHX35 (DEAH-box helicase 35)

Identity

Alias_namesC20orf15
DDX35
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
Alias_symbol (synonym)FLJ22759
KAIA0875
Other alias
HGNC (Hugo) DHX35
LocusID (NCBI) 60625
Atlas_Id 47444
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 37590981 and ends at 37668366 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DHX35 (20q11.23) / DNTTIP1 (20q13.12)DHX35 (20q11.23) / ITCH (20q11.22)DHX35 20q11.23 / DNTTIP1 20q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX35   15861
Cards
Entrez_Gene (NCBI)DHX35  60625  DEAH-box helicase 35
AliasesC20orf15; DDX35; KAIA0875
GeneCards (Weizmann)DHX35
Ensembl hg19 (Hinxton)ENSG00000101452 [Gene_View]  chr20:37590981-37668366 [Contig_View]  DHX35 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101452 [Gene_View]  chr20:37590981-37668366 [Contig_View]  DHX35 [Vega]
ICGC DataPortalENSG00000101452
TCGA cBioPortalDHX35
AceView (NCBI)DHX35
Genatlas (Paris)DHX35
WikiGenes60625
SOURCE (Princeton)DHX35
Genetics Home Reference (NIH)DHX35
Genomic and cartography
GoldenPath hg19 (UCSC)DHX35  -     chr20:37590981-37668366 +  20q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DHX35  -     20q11.23   [Description]    (hg38-Dec_2013)
EnsemblDHX35 - 20q11.23 [CytoView hg19]  DHX35 - 20q11.23 [CytoView hg38]
Mapping of homologs : NCBIDHX35 [Mapview hg19]  DHX35 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK025541 AK026412 AK056710 AK296506 AK296793
RefSeq transcript (Entrez)NM_001190809 NM_021931
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)DHX35
Cluster EST : UnigeneHs.444520 [ NCBI ]
CGAP (NCI)Hs.444520
Alternative Splicing GalleryENSG00000101452
Gene ExpressionDHX35 [ NCBI-GEO ]   DHX35 [ EBI - ARRAY_EXPRESS ]   DHX35 [ SEEK ]   DHX35 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60625
GTEX Portal (Tissue expression)DHX35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H5Z1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H5Z1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H5Z1
Splice isoforms : SwissVarQ9H5Z1
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9H5Z1
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
Conserved Domain (NCBI)DHX35
DMDM Disease mutations60625
Blocks (Seattle)DHX35
SuperfamilyQ9H5Z1
Human Protein AtlasENSG00000101452
Peptide AtlasQ9H5Z1
HPRD13145
IPIIPI00030288   IPI00909339   IPI00514896   IPI00513682   IPI00642913   IPI01009669   
Protein Interaction databases
DIP (DOE-UCLA)Q9H5Z1
IntAct (EBI)Q9H5Z1
FunCoupENSG00000101452
BioGRIDDHX35
STRING (EMBL)DHX35
ZODIACDHX35
Ontologies - Pathways
QuickGOQ9H5Z1
Ontology : AmiGOmRNA splicing, via spliceosome  ATP-dependent RNA helicase activity  ATP binding  cytoplasm  RNA processing  poly(A) RNA binding  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  ATP-dependent RNA helicase activity  ATP binding  cytoplasm  RNA processing  poly(A) RNA binding  catalytic step 2 spliceosome  
NDEx NetworkDHX35
Atlas of Cancer Signalling NetworkDHX35
Wikipedia pathwaysDHX35
Orthology - Evolution
OrthoDB60625
GeneTree (enSembl)ENSG00000101452
Phylogenetic Trees/Animal Genes : TreeFamDHX35
HOVERGENQ9H5Z1
HOGENOMQ9H5Z1
Homologs : HomoloGeneDHX35
Homology/Alignments : Family Browser (UCSC)DHX35
Gene fusions - Rearrangements
Fusion : MitelmanDHX35/DNTTIP1 [20q11.23/20q13.12]  
Fusion : MitelmanDHX35/ITCH [20q11.23/20q11.22]  [t(20;20)(q11;q12)]  
Fusion: TCGADHX35 20q11.23 DNTTIP1 20q13.12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHX35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX35
dbVarDHX35
ClinVarDHX35
1000_GenomesDHX35 
Exome Variant ServerDHX35
ExAC (Exome Aggregation Consortium)DHX35 (select the gene name)
Genetic variants : HAPMAP60625
Genomic Variants (DGV)DHX35 [DGVbeta]
DECIPHER (Syndromes)20:37590981-37668366  ENSG00000101452
CONAN: Copy Number AnalysisDHX35 
Mutations
ICGC Data PortalDHX35 
TCGA Data PortalDHX35 
Broad Tumor PortalDHX35
OASIS PortalDHX35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHX35
intOGen PortalDHX35
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX35
DgiDB (Drug Gene Interaction Database)DHX35
DoCM (Curated mutations)DHX35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX35 (select a term)
intoGenDHX35
Cancer3DDHX35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDHX35
Genetic Testing Registry DHX35
NextProtQ9H5Z1 [Medical]
TSGene60625
GENETestsDHX35
Huge Navigator DHX35 [HugePedia]
snp3D : Map Gene to Disease60625
BioCentury BCIQDHX35
ClinGenDHX35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD60625
Chemical/Pharm GKB GenePA27222
Clinical trialDHX35
Miscellaneous
canSAR (ICR)DHX35 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX35
EVEXDHX35
GoPubMedDHX35
iHOPDHX35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:58:51 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.