Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DHX36 (DEAH-box helicase 36)

Identity

Alias_namesDDX36
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
Alias_symbol (synonym)MLEL1
KIAA1488
Other aliasG4R1
RHAU
HGNC (Hugo) DHX36
LocusID (NCBI) 170506
Atlas_Id 46686
Location 3q25.2  [Link to chromosome band 3q25]
Location_base_pair Starts at 153993457 and ends at 154042286 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DHX36 (3q25.2) / DHX36 (3q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX36   14410
Cards
Entrez_Gene (NCBI)DHX36  170506  DEAH-box helicase 36
AliasesDDX36; G4R1; MLEL1; RHAU
GeneCards (Weizmann)DHX36
Ensembl hg19 (Hinxton)ENSG00000174953 [Gene_View]  chr3:153993457-154042286 [Contig_View]  DHX36 [Vega]
Ensembl hg38 (Hinxton)ENSG00000174953 [Gene_View]  chr3:153993457-154042286 [Contig_View]  DHX36 [Vega]
ICGC DataPortalENSG00000174953
TCGA cBioPortalDHX36
AceView (NCBI)DHX36
Genatlas (Paris)DHX36
WikiGenes170506
SOURCE (Princeton)DHX36
Genetics Home Reference (NIH)DHX36
Genomic and cartography
GoldenPath hg19 (UCSC)DHX36  -     chr3:153993457-154042286 -  3q25.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DHX36  -     3q25.2   [Description]    (hg38-Dec_2013)
EnsemblDHX36 - 3q25.2 [CytoView hg19]  DHX36 - 3q25.2 [CytoView hg38]
Mapping of homologs : NCBIDHX36 [Mapview hg19]  DHX36 [Mapview hg38]
OMIM612767   
Gene and transcription
Genbank (Entrez)AB040921 AF217190 AJ577133 AJ577134 AK096808
RefSeq transcript (Entrez)NM_001114397 NM_020865
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NT_187533 NW_004929311
Consensus coding sequences : CCDS (NCBI)DHX36
Cluster EST : UnigeneHs.446270 [ NCBI ]
CGAP (NCI)Hs.446270
Alternative Splicing GalleryENSG00000174953
Gene ExpressionDHX36 [ NCBI-GEO ]   DHX36 [ EBI - ARRAY_EXPRESS ]   DHX36 [ SEEK ]   DHX36 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX36 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)170506
GTEX Portal (Tissue expression)DHX36
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2U1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2U1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2U1
Splice isoforms : SwissVarQ9H2U1
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.123.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
PhosPhoSitePlusQ9H2U1
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
Conserved Domain (NCBI)DHX36
DMDM Disease mutations170506
Blocks (Seattle)DHX36
PDB (SRS)2N16    2N21   
PDB (PDBSum)2N16    2N21   
PDB (IMB)2N16    2N21   
PDB (RSDB)2N16    2N21   
Structural Biology KnowledgeBase2N16    2N21   
SCOP (Structural Classification of Proteins)2N16    2N21   
CATH (Classification of proteins structures)2N16    2N21   
SuperfamilyQ9H2U1
Human Protein AtlasENSG00000174953
Peptide AtlasQ9H2U1
HPRD09918
IPIIPI00027415   IPI00784170   IPI00217760   IPI00922725   IPI00945848   IPI00946744   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2U1
IntAct (EBI)Q9H2U1
FunCoupENSG00000174953
BioGRIDDHX36
STRING (EMBL)DHX36
ZODIACDHX36
Ontologies - Pathways
QuickGOQ9H2U1
Ontology : AmiGOchromosome, telomeric region  core promoter binding  ossification  G-quadruplex RNA binding  double-stranded RNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleus  cytoplasm  cytoplasm  cytosol  transcription, DNA-templated  RNA processing  DNA-dependent ATPase activity  response to virus  RNA secondary structure unwinding  positive regulation of telomere maintenance  positive regulation of type I interferon production  histone deacetylase binding  response to exogenous dsRNA  transcription regulatory region DNA binding  poly(A) RNA binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase II promoter  G-quadruplex DNA binding  extracellular exosome  
Ontology : EGO-EBIchromosome, telomeric region  core promoter binding  ossification  G-quadruplex RNA binding  double-stranded RNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleus  cytoplasm  cytoplasm  cytosol  transcription, DNA-templated  RNA processing  DNA-dependent ATPase activity  response to virus  RNA secondary structure unwinding  positive regulation of telomere maintenance  positive regulation of type I interferon production  histone deacetylase binding  response to exogenous dsRNA  transcription regulatory region DNA binding  poly(A) RNA binding  poly(A) RNA binding  positive regulation of transcription from RNA polymerase II promoter  G-quadruplex DNA binding  extracellular exosome  
Pathways : KEGGRNA degradation   
NDEx NetworkDHX36
Atlas of Cancer Signalling NetworkDHX36
Wikipedia pathwaysDHX36
Orthology - Evolution
OrthoDB170506
GeneTree (enSembl)ENSG00000174953
Phylogenetic Trees/Animal Genes : TreeFamDHX36
HOVERGENQ9H2U1
HOGENOMQ9H2U1
Homologs : HomoloGeneDHX36
Homology/Alignments : Family Browser (UCSC)DHX36
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHX36 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX36
dbVarDHX36
ClinVarDHX36
1000_GenomesDHX36 
Exome Variant ServerDHX36
ExAC (Exome Aggregation Consortium)DHX36 (select the gene name)
Genetic variants : HAPMAP170506
Genomic Variants (DGV)DHX36 [DGVbeta]
DECIPHER (Syndromes)3:153993457-154042286  ENSG00000174953
CONAN: Copy Number AnalysisDHX36 
Mutations
ICGC Data PortalDHX36 
TCGA Data PortalDHX36 
Broad Tumor PortalDHX36
OASIS PortalDHX36 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX36  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHX36
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX36
DgiDB (Drug Gene Interaction Database)DHX36
DoCM (Curated mutations)DHX36 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX36 (select a term)
intoGenDHX36
Cancer3DDHX36(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612767   
Orphanet
MedgenDHX36
Genetic Testing Registry DHX36
NextProtQ9H2U1 [Medical]
TSGene170506
GENETestsDHX36
Huge Navigator DHX36 [HugePedia]
snp3D : Map Gene to Disease170506
BioCentury BCIQDHX36
ClinGenDHX36
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD170506
Chemical/Pharm GKB GenePA27223
Clinical trialDHX36
Miscellaneous
canSAR (ICR)DHX36 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX36
EVEXDHX36
GoPubMedDHX36
iHOPDHX36
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:58:51 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.