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DHX37 (DEAH-box helicase 37)

Identity

Alias_namesDDX37
DEAD/DEAH box helicase DDX37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
Alias_symbol (synonym)KIAA1517
MGC4322
MGC2695
Other alias
HGNC (Hugo) DHX37
LocusID (NCBI) 57647
Atlas_Id 47074
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 124946824 and ends at 124989121 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NCOR2 (12q24.31) / DHX37 (12q24.31)SCARB1 (12q24.31) / DHX37 (12q24.31)NCOR2 12q24.31 / DHX37 12q24.31
SCARB1 12q24.31 / DHX37 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX37   17210
Cards
Entrez_Gene (NCBI)DHX37  57647  DEAH-box helicase 37
AliasesDDX37
GeneCards (Weizmann)DHX37
Ensembl hg19 (Hinxton)ENSG00000150990 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000150990 [Gene_View]  chr12:124946824-124989121 [Contig_View]  DHX37 [Vega]
ICGC DataPortalENSG00000150990
TCGA cBioPortalDHX37
AceView (NCBI)DHX37
Genatlas (Paris)DHX37
WikiGenes57647
SOURCE (Princeton)DHX37
Genetics Home Reference (NIH)DHX37
Genomic and cartography
GoldenPath hg38 (UCSC)DHX37  -     chr12:124946824-124989121 -  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHX37  -     12q24.31   [Description]    (hg19-Feb_2009)
EnsemblDHX37 - 12q24.31 [CytoView hg19]  DHX37 - 12q24.31 [CytoView hg38]
Mapping of homologs : NCBIDHX37 [Mapview hg19]  DHX37 [Mapview hg38]
OMIM617362   
Gene and transcription
Genbank (Entrez)AB040950 AK123968 BC002575 BC004463 BC009913
RefSeq transcript (Entrez)NM_032656
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHX37
Cluster EST : UnigeneHs.107382 [ NCBI ]
CGAP (NCI)Hs.107382
Alternative Splicing GalleryENSG00000150990
Gene ExpressionDHX37 [ NCBI-GEO ]   DHX37 [ EBI - ARRAY_EXPRESS ]   DHX37 [ SEEK ]   DHX37 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX37 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57647
GTEX Portal (Tissue expression)DHX37
Human Protein AtlasENSG00000150990-DHX37 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IY37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IY37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IY37
Splice isoforms : SwissVarQ8IY37
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ8IY37
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
Conserved Domain (NCBI)DHX37
DMDM Disease mutations57647
Blocks (Seattle)DHX37
SuperfamilyQ8IY37
Human Protein Atlas [tissue]ENSG00000150990-DHX37 [tissue]
Peptide AtlasQ8IY37
HPRD10883
IPIIPI00217630   IPI01015592   
Protein Interaction databases
DIP (DOE-UCLA)Q8IY37
IntAct (EBI)Q8IY37
FunCoupENSG00000150990
BioGRIDDHX37
STRING (EMBL)DHX37
ZODIACDHX37
Ontologies - Pathways
QuickGOQ8IY37
Ontology : AmiGOnucleic acid binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  nucleolus  cytoplasm  rRNA processing  RNA processing  
Ontology : EGO-EBInucleic acid binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  nucleolus  cytoplasm  rRNA processing  RNA processing  
NDEx NetworkDHX37
Atlas of Cancer Signalling NetworkDHX37
Wikipedia pathwaysDHX37
Orthology - Evolution
OrthoDB57647
GeneTree (enSembl)ENSG00000150990
Phylogenetic Trees/Animal Genes : TreeFamDHX37
HOVERGENQ8IY37
HOGENOMQ8IY37
Homologs : HomoloGeneDHX37
Homology/Alignments : Family Browser (UCSC)DHX37
Gene fusions - Rearrangements
Fusion : MitelmanNCOR2/DHX37 [12q24.31/12q24.31]  [t(12;12)(q24;q24)]  
Fusion : MitelmanSCARB1/DHX37 [12q24.31/12q24.31]  [t(12;12)(q24;q24)]  
Fusion: TCGA_MDACCNCOR2 12q24.31 DHX37 12q24.31 GBM
Fusion: TCGA_MDACCSCARB1 12q24.31 DHX37 12q24.31 BRCA
Tumor Fusion PortalDHX37
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHX37 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX37
dbVarDHX37
ClinVarDHX37
1000_GenomesDHX37 
Exome Variant ServerDHX37
ExAC (Exome Aggregation Consortium)ENSG00000150990
GNOMAD BrowserENSG00000150990
Genetic variants : HAPMAP57647
Genomic Variants (DGV)DHX37 [DGVbeta]
DECIPHERDHX37 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHX37 
Mutations
ICGC Data PortalDHX37 
TCGA Data PortalDHX37 
Broad Tumor PortalDHX37
OASIS PortalDHX37 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX37  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHX37
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX37
DgiDB (Drug Gene Interaction Database)DHX37
DoCM (Curated mutations)DHX37 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX37 (select a term)
intoGenDHX37
Cancer3DDHX37(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617362   
Orphanet
DisGeNETDHX37
MedgenDHX37
Genetic Testing Registry DHX37
NextProtQ8IY37 [Medical]
TSGene57647
GENETestsDHX37
Target ValidationDHX37
Huge Navigator DHX37 [HugePedia]
snp3D : Map Gene to Disease57647
BioCentury BCIQDHX37
ClinGenDHX37
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57647
Chemical/Pharm GKB GenePA27224
Clinical trialDHX37
Miscellaneous
canSAR (ICR)DHX37 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX37
EVEXDHX37
GoPubMedDHX37
iHOPDHX37
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:10:33 CET 2017

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