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DIMT1 (DIM1 rRNA methyltransferase and ribosome maturation factor)

Identity

Alias (NCBI)DIM1
DIMT1L
HSA9761
HUSSY5
HGNC (Hugo) DIMT1
HGNC Alias symbHSA9761
HGNC Previous nameDIMT1L
HGNC Previous nameDIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
 DIMT1 rRNA methyltransferase and ribosome maturation factor
LocusID (NCBI) 27292
Atlas_Id 56066
Location 5q12.1  [Link to chromosome band 5q12]
Location_base_pair Starts at 62387254 and ends at 62403905 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DIMT1 (5q12.1) / RNF144B (6p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DIMT1   30217
Cards
Entrez_Gene (NCBI)DIMT1    DIM1 rRNA methyltransferase and ribosome maturation factor
AliasesDIM1; DIMT1L; HSA9761; HUSSY5
GeneCards (Weizmann)DIMT1
Ensembl hg19 (Hinxton)ENSG00000086189 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086189 [Gene_View]  ENSG00000086189 [Sequence]  chr5:62387254-62403905 [Contig_View]  DIMT1 [Vega]
ICGC DataPortalENSG00000086189
TCGA cBioPortalDIMT1
AceView (NCBI)DIMT1
Genatlas (Paris)DIMT1
SOURCE (Princeton)DIMT1
Genetics Home Reference (NIH)DIMT1
Genomic and cartography
GoldenPath hg38 (UCSC)DIMT1  -     chr5:62387254-62403905 -  5q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DIMT1  -     5q12.1   [Description]    (hg19-Feb_2009)
GoldenPathDIMT1 - 5q12.1 [CytoView hg19]  DIMT1 - 5q12.1 [CytoView hg38]
ImmunoBaseENSG00000086189
Genome Data Viewer NCBIDIMT1 [Mapview hg19]  
OMIM612499   
Gene and transcription
Genbank (Entrez)AF091078 AF102147 AJ009761 AK292723 AK299480
RefSeq transcript (Entrez)NM_001348076 NM_001348077 NM_014473
Consensus coding sequences : CCDS (NCBI)DIMT1
Gene ExpressionDIMT1 [ NCBI-GEO ]   DIMT1 [ EBI - ARRAY_EXPRESS ]   DIMT1 [ SEEK ]   DIMT1 [ MEM ]
Gene Expression Viewer (FireBrowse)DIMT1 [ Firebrowse - Broad ]
GenevisibleExpression of DIMT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27292
GTEX Portal (Tissue expression)DIMT1
Human Protein AtlasENSG00000086189-DIMT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNQ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNQ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNQ2
PhosPhoSitePlusQ9UNQ2
Domaine pattern : Prosite (Expaxy)RRNA_A_DIMETH (PS01131)    SAM_RNA_A_N6_MT (PS51689)   
Domains : Interpro (EBI)KsgA/Erm    rRNA_Ade_Mease_Trfase_CS    rRNA_Ade_methylase_Trfase_N    rRNA_adenine_dimethylase    SAM-dependent_MTases   
Domain families : Pfam (Sanger)RrnaAD (PF00398)   
Domain families : Pfam (NCBI)pfam00398   
Domain families : Smart (EMBL)rADc (SM00650)  
Conserved Domain (NCBI)DIMT1
PDB (RSDB)1ZQ9    6W6C    6W6F   
PDB Europe1ZQ9    6W6C    6W6F   
PDB (PDBSum)1ZQ9    6W6C    6W6F   
PDB (IMB)1ZQ9    6W6C    6W6F   
Structural Biology KnowledgeBase1ZQ9    6W6C    6W6F   
SCOP (Structural Classification of Proteins)1ZQ9    6W6C    6W6F   
CATH (Classification of proteins structures)1ZQ9    6W6C    6W6F   
SuperfamilyQ9UNQ2
AlphaFold pdb e-kbQ9UNQ2   
Human Protein Atlas [tissue]ENSG00000086189-DIMT1 [tissue]
HPRD13676
Protein Interaction databases
DIP (DOE-UCLA)Q9UNQ2
IntAct (EBI)Q9UNQ2
BioGRIDDIMT1
STRING (EMBL)DIMT1
ZODIACDIMT1
Ontologies - Pathways
QuickGOQ9UNQ2
Ontology : AmiGOrRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  RNA binding  nucleoplasm  nucleoplasm  nucleolus  mitochondrial matrix  cytosol  rRNA methylation  rRNA methylation  rRNA methylation  18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity  positive regulation of rRNA processing  
Ontology : EGO-EBIrRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  rRNA (adenine-N6,N6-)-dimethyltransferase activity  RNA binding  nucleoplasm  nucleoplasm  nucleolus  mitochondrial matrix  cytosol  rRNA methylation  rRNA methylation  rRNA methylation  18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity  positive regulation of rRNA processing  
NDEx NetworkDIMT1
Atlas of Cancer Signalling NetworkDIMT1
Wikipedia pathwaysDIMT1
Orthology - Evolution
OrthoDB27292
GeneTree (enSembl)ENSG00000086189
Phylogenetic Trees/Animal Genes : TreeFamDIMT1
Homologs : HomoloGeneDIMT1
Homology/Alignments : Family Browser (UCSC)DIMT1
Gene fusions - Rearrangements
Fusion : QuiverDIMT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDIMT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DIMT1
dbVarDIMT1
ClinVarDIMT1
MonarchDIMT1
1000_GenomesDIMT1 
Exome Variant ServerDIMT1
GNOMAD BrowserENSG00000086189
Varsome BrowserDIMT1
ACMGDIMT1 variants
VarityQ9UNQ2
Genomic Variants (DGV)DIMT1 [DGVbeta]
DECIPHERDIMT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDIMT1 
Mutations
ICGC Data PortalDIMT1 
TCGA Data PortalDIMT1 
Broad Tumor PortalDIMT1
OASIS PortalDIMT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDIMT1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDIMT1
Mutations and Diseases : HGMDDIMT1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDIMT1
DgiDB (Drug Gene Interaction Database)DIMT1
DoCM (Curated mutations)DIMT1
CIViC (Clinical Interpretations of Variants in Cancer)DIMT1
Cancer3DDIMT1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612499   
Orphanet
DisGeNETDIMT1
MedgenDIMT1
Genetic Testing Registry DIMT1
NextProtQ9UNQ2 [Medical]
GENETestsDIMT1
Target ValidationDIMT1
Huge Navigator DIMT1 [HugePedia]
ClinGenDIMT1
Clinical trials, drugs, therapy
MyCancerGenomeDIMT1
Protein Interactions : CTDDIMT1
Pharm GKB GenePA162383599
PharosQ9UNQ2
Clinical trialDIMT1
Miscellaneous
canSAR (ICR)DIMT1
HarmonizomeDIMT1
DataMed IndexDIMT1
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDIMT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:06:44 CEST 2021

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