DIP2A (disco interacting protein 2 homolog A)

2021-06-01  

Identity

HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
C21orf106,DIP2

Other Information

Locus ID:

NCBI: 23181
MIM: 607711
HGNC: 17217
Ensembl: ENSG00000160305

Variants:

dbSNP: 23181
ClinVar: 23181
TCGA: ENSG00000160305
COSMIC: DIP2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000160305ENST00000400274Q14689
ENSG00000160305ENST00000417564Q14689
ENSG00000160305ENST00000435722Q14689
ENSG00000160305ENST00000457905Q14689
ENSG00000160305ENST00000466639Q14689
ENSG00000160305ENST00000651436A0A494C143

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
200540022010DIP2A functions as a FSTL1 receptor.36
208606222010DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.26
264523392016Genetic variant in DIP2A gene is associated with developmental dyslexia in Chinese population.10
305421202019Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma.4
301106362018Blocking the FSTL1-DIP2A Axis Improves Anti-tumor Immunity.2

Citation

Dessen P

DIP2A (disco interacting protein 2 homolog A)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58277/dip2a