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DIRAS2 (DIRAS family GTPase 2)

Identity

Alias_namesDIRAS family
Alias_symbol (synonym)Di-Ras2
DKFZp761C07121
Other alias
HGNC (Hugo) DIRAS2
LocusID (NCBI) 54769
Atlas_Id 43230
Location 9q22.2  [Link to chromosome band 9q22]
Location_base_pair Starts at 90609832 and ends at 90643105 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DIRAS2 (9q22.2) / COMMD1 (2p15)DIRAS2 (9q22.2) / DIRAS2 (9q22.2)DIRAS2 (9q22.2) / GNA14 (9q21.2)
DIRAS2 9q22.2 / GNA14 9q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DIRAS2   19323
Cards
Entrez_Gene (NCBI)DIRAS2  54769  DIRAS family GTPase 2
AliasesDi-Ras2
GeneCards (Weizmann)DIRAS2
Ensembl hg19 (Hinxton)ENSG00000165023 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165023 [Gene_View]  chr9:90609832-90643105 [Contig_View]  DIRAS2 [Vega]
ICGC DataPortalENSG00000165023
TCGA cBioPortalDIRAS2
AceView (NCBI)DIRAS2
Genatlas (Paris)DIRAS2
WikiGenes54769
SOURCE (Princeton)DIRAS2
Genetics Home Reference (NIH)DIRAS2
Genomic and cartography
GoldenPath hg38 (UCSC)DIRAS2  -     chr9:90609832-90643105 -  9q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DIRAS2  -     9q22.2   [Description]    (hg19-Feb_2009)
EnsemblDIRAS2 - 9q22.2 [CytoView hg19]  DIRAS2 - 9q22.2 [CytoView hg38]
Mapping of homologs : NCBIDIRAS2 [Mapview hg19]  DIRAS2 [Mapview hg38]
OMIM607863   
Gene and transcription
Genbank (Entrez)AB076889 AK122986 AK124628 AL137308 BC008065
RefSeq transcript (Entrez)NM_017594
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DIRAS2
Cluster EST : UnigeneHs.165636 [ NCBI ]
CGAP (NCI)Hs.165636
Alternative Splicing GalleryENSG00000165023
Gene ExpressionDIRAS2 [ NCBI-GEO ]   DIRAS2 [ EBI - ARRAY_EXPRESS ]   DIRAS2 [ SEEK ]   DIRAS2 [ MEM ]
Gene Expression Viewer (FireBrowse)DIRAS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54769
GTEX Portal (Tissue expression)DIRAS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HU8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HU8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HU8
Splice isoforms : SwissVarQ96HU8
PhosPhoSitePlusQ96HU8
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Conserved Domain (NCBI)DIRAS2
DMDM Disease mutations54769
Blocks (Seattle)DIRAS2
PDB (SRS)2ERX   
PDB (PDBSum)2ERX   
PDB (IMB)2ERX   
PDB (RSDB)2ERX   
Structural Biology KnowledgeBase2ERX   
SCOP (Structural Classification of Proteins)2ERX   
CATH (Classification of proteins structures)2ERX   
SuperfamilyQ96HU8
Human Protein AtlasENSG00000165023
Peptide AtlasQ96HU8
HPRD09711
IPIIPI00063302   
Protein Interaction databases
DIP (DOE-UCLA)Q96HU8
IntAct (EBI)Q96HU8
FunCoupENSG00000165023
BioGRIDDIRAS2
STRING (EMBL)DIRAS2
ZODIACDIRAS2
Ontologies - Pathways
QuickGOQ96HU8
Ontology : AmiGOGTPase activity  GTP binding  plasma membrane  signal transduction  positive regulation of MAP kinase activity  
Ontology : EGO-EBIGTPase activity  GTP binding  plasma membrane  signal transduction  positive regulation of MAP kinase activity  
NDEx NetworkDIRAS2
Atlas of Cancer Signalling NetworkDIRAS2
Wikipedia pathwaysDIRAS2
Orthology - Evolution
OrthoDB54769
GeneTree (enSembl)ENSG00000165023
Phylogenetic Trees/Animal Genes : TreeFamDIRAS2
HOVERGENQ96HU8
HOGENOMQ96HU8
Homologs : HomoloGeneDIRAS2
Homology/Alignments : Family Browser (UCSC)DIRAS2
Gene fusions - Rearrangements
Fusion : MitelmanDIRAS2/GNA14 [9q22.2/9q21.2]  
Fusion: TCGADIRAS2 9q22.2 GNA14 9q21.2 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDIRAS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DIRAS2
dbVarDIRAS2
ClinVarDIRAS2
1000_GenomesDIRAS2 
Exome Variant ServerDIRAS2
ExAC (Exome Aggregation Consortium)DIRAS2 (select the gene name)
Genetic variants : HAPMAP54769
Genomic Variants (DGV)DIRAS2 [DGVbeta]
DECIPHERDIRAS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDIRAS2 
Mutations
ICGC Data PortalDIRAS2 
TCGA Data PortalDIRAS2 
Broad Tumor PortalDIRAS2
OASIS PortalDIRAS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDIRAS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDIRAS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DIRAS2
DgiDB (Drug Gene Interaction Database)DIRAS2
DoCM (Curated mutations)DIRAS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DIRAS2 (select a term)
intoGenDIRAS2
Cancer3DDIRAS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607863   
Orphanet
MedgenDIRAS2
Genetic Testing Registry DIRAS2
NextProtQ96HU8 [Medical]
TSGene54769
GENETestsDIRAS2
Huge Navigator DIRAS2 [HugePedia]
snp3D : Map Gene to Disease54769
BioCentury BCIQDIRAS2
ClinGenDIRAS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54769
Chemical/Pharm GKB GenePA134958969
Clinical trialDIRAS2
Miscellaneous
canSAR (ICR)DIRAS2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDIRAS2
EVEXDIRAS2
GoPubMedDIRAS2
iHOPDIRAS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:13:19 CEST 2017

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