Identity
HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
FAM6A,PRLMNS,hDIS3L2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 129563
MIM: 614184
HGNC: 28648
Ensembl: ENSG00000144535
Variants:
dbSNP: 129563
ClinVar: 129563
TCGA: ENSG00000144535
COSMIC: DIS3L2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37340282 | 2023 | DIS3L2 knockdown impairs key oncogenic properties of colorectal cancer cells via the mTOR signaling pathway. | 1 |
| 37340282 | 2023 | DIS3L2 knockdown impairs key oncogenic properties of colorectal cancer cells via the mTOR signaling pathway. | 1 |
| 32374871 | 2020 | DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAs. | 8 |
| 32457326 | 2020 | The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. | 9 |
| 32488030 | 2020 | AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. | 44 |
| 32374871 | 2020 | DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAs. | 8 |
| 32457326 | 2020 | The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. | 9 |
| 32488030 | 2020 | AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. | 44 |
| 31331910 | 2019 | DIS3L2 Promotes Progression of Hepatocellular Carcinoma via hnRNP U-Mediated Alternative Splicing. | 24 |
| 31466720 | 2019 | A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells. | 8 |
| 31331910 | 2019 | DIS3L2 Promotes Progression of Hepatocellular Carcinoma via hnRNP U-Mediated Alternative Splicing. | 24 |
| 31466720 | 2019 | A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells. | 8 |
| 29100804 | 2018 | Immunohistochemical localization of exoribonucleases (DIS3L2 and XRN1) in intranuclear inclusion body disease. | 7 |
| 29100804 | 2018 | Immunohistochemical localization of exoribonucleases (DIS3L2 and XRN1) in intranuclear inclusion body disease. | 7 |
| 27881476 | 2017 | Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively. | 19 |
Citation
Dessen P
DIS3L2 (DIS3 like 3-5 exoribonuclease 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-04-01
Online version: http://atlasgeneticsoncology.org/gene/52692/dis3l2
