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DIXDC1 (DIX domain containing 1)

Identity

Alias_symbol (synonym)KIAA1735
Dixin
Other aliasCCD1
HGNC (Hugo) DIXDC1
LocusID (NCBI) 85458
Atlas_Id 50814
Location 11q23.1  [Link to chromosome band 11q23]
Location_base_pair Starts at 111807927 and ends at 111893374 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DIXDC1 (11q23.1) / DIXDC1 (11q23.1)DIXDC1 (11q23.1) / GAB2 (11q14.1)DIXDC1 (11q23.1) / MCF2 (Xq27.1)
LOC728190 () / DIXDC1 (11q23.1)DIXDC1 11q23.1 / GAB2 11q14.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DIXDC1   23695
Cards
Entrez_Gene (NCBI)DIXDC1  85458  DIX domain containing 1
AliasesCCD1
GeneCards (Weizmann)DIXDC1
Ensembl hg19 (Hinxton)ENSG00000150764 [Gene_View]  chr11:111807927-111893374 [Contig_View]  DIXDC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000150764 [Gene_View]  chr11:111807927-111893374 [Contig_View]  DIXDC1 [Vega]
ICGC DataPortalENSG00000150764
TCGA cBioPortalDIXDC1
AceView (NCBI)DIXDC1
Genatlas (Paris)DIXDC1
WikiGenes85458
SOURCE (Princeton)DIXDC1
Genetics Home Reference (NIH)DIXDC1
Genomic and cartography
GoldenPath hg19 (UCSC)DIXDC1  -     chr11:111807927-111893374 +  11q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DIXDC1  -     11q23.1   [Description]    (hg38-Dec_2013)
EnsemblDIXDC1 - 11q23.1 [CytoView hg19]  DIXDC1 - 11q23.1 [CytoView hg38]
Mapping of homologs : NCBIDIXDC1 [Mapview hg19]  DIXDC1 [Mapview hg38]
OMIM610493   
Gene and transcription
Genbank (Entrez)AB051522 AB074187 AF070621 AK055469 AK055899
RefSeq transcript (Entrez)NM_001037954 NM_001278542 NM_033425
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_033127 NT_033899 NW_004929381
Consensus coding sequences : CCDS (NCBI)DIXDC1
Cluster EST : UnigeneHs.655626 [ NCBI ]
CGAP (NCI)Hs.655626
Alternative Splicing GalleryENSG00000150764
Gene ExpressionDIXDC1 [ NCBI-GEO ]   DIXDC1 [ EBI - ARRAY_EXPRESS ]   DIXDC1 [ SEEK ]   DIXDC1 [ MEM ]
Gene Expression Viewer (FireBrowse)DIXDC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85458
GTEX Portal (Tissue expression)DIXDC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ155Q3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ155Q3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ155Q3
Splice isoforms : SwissVarQ155Q3
PhosPhoSitePlusQ155Q3
Domaine pattern : Prosite (Expaxy)CH (PS50021)    DIX (PS50841)   
Domains : Interpro (EBI)CH-domain    DIX    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)CH (PF00307)    DIX (PF00778)   
Domain families : Pfam (NCBI)pfam00307    pfam00778   
Domain families : Smart (EMBL)CH (SM00033)  
Conserved Domain (NCBI)DIXDC1
DMDM Disease mutations85458
Blocks (Seattle)DIXDC1
PDB (SRS)3PZ7   
PDB (PDBSum)3PZ7   
PDB (IMB)3PZ7   
PDB (RSDB)3PZ7   
Structural Biology KnowledgeBase3PZ7   
SCOP (Structural Classification of Proteins)3PZ7   
CATH (Classification of proteins structures)3PZ7   
SuperfamilyQ155Q3
Human Protein AtlasENSG00000150764
Peptide AtlasQ155Q3
HPRD16804
IPIIPI00783746   IPI00028306   IPI00845284   IPI00440194   IPI00922605   IPI00719830   
Protein Interaction databases
DIP (DOE-UCLA)Q155Q3
IntAct (EBI)Q155Q3
FunCoupENSG00000150764
BioGRIDDIXDC1
STRING (EMBL)DIXDC1
ZODIACDIXDC1
Ontologies - Pathways
QuickGOQ155Q3
Ontology : AmiGOactin binding  protein binding  cytoplasm  cytosol  focal adhesion  cell cycle  protein domain specific binding  cerebral cortex radially oriented cell migration  forebrain ventricular zone progenitor cell division  regulation of actin cytoskeleton organization  gamma-tubulin binding  negative regulation of neuron differentiation  canonical Wnt signaling pathway  regulation of microtubule cytoskeleton organization  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  cytosol  focal adhesion  cell cycle  protein domain specific binding  cerebral cortex radially oriented cell migration  forebrain ventricular zone progenitor cell division  regulation of actin cytoskeleton organization  gamma-tubulin binding  negative regulation of neuron differentiation  canonical Wnt signaling pathway  regulation of microtubule cytoskeleton organization  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkDIXDC1
Atlas of Cancer Signalling NetworkDIXDC1
Wikipedia pathwaysDIXDC1
Orthology - Evolution
OrthoDB85458
GeneTree (enSembl)ENSG00000150764
Phylogenetic Trees/Animal Genes : TreeFamDIXDC1
HOVERGENQ155Q3
HOGENOMQ155Q3
Homologs : HomoloGeneDIXDC1
Homology/Alignments : Family Browser (UCSC)DIXDC1
Gene fusions - Rearrangements
Fusion : MitelmanDIXDC1/GAB2 [11q23.1/11q14.1]  
Fusion: TCGADIXDC1 11q23.1 GAB2 11q14.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDIXDC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DIXDC1
dbVarDIXDC1
ClinVarDIXDC1
1000_GenomesDIXDC1 
Exome Variant ServerDIXDC1
ExAC (Exome Aggregation Consortium)DIXDC1 (select the gene name)
Genetic variants : HAPMAP85458
Genomic Variants (DGV)DIXDC1 [DGVbeta]
DECIPHER (Syndromes)11:111807927-111893374  ENSG00000150764
CONAN: Copy Number AnalysisDIXDC1 
Mutations
ICGC Data PortalDIXDC1 
TCGA Data PortalDIXDC1 
Broad Tumor PortalDIXDC1
OASIS PortalDIXDC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDIXDC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDIXDC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DIXDC1
DgiDB (Drug Gene Interaction Database)DIXDC1
DoCM (Curated mutations)DIXDC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DIXDC1 (select a term)
intoGenDIXDC1
Cancer3DDIXDC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610493   
Orphanet
MedgenDIXDC1
Genetic Testing Registry DIXDC1
NextProtQ155Q3 [Medical]
TSGene85458
GENETestsDIXDC1
Huge Navigator DIXDC1 [HugePedia]
snp3D : Map Gene to Disease85458
BioCentury BCIQDIXDC1
ClinGenDIXDC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85458
Chemical/Pharm GKB GenePA134988674
Clinical trialDIXDC1
Miscellaneous
canSAR (ICR)DIXDC1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDIXDC1
EVEXDIXDC1
GoPubMedDIXDC1
iHOPDIXDC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:58:56 CEST 2017

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