DLGAP1 (DLG associated protein 1)

2019-04-01  

Identity

HGNC
LOCATION
18p11.31
LOCUSID
ALIAS
DAP-1,DAP-1-ALPHA,DAP-1-BETA,DAP1,DLGAP1A,DLGAP1B,GKAP,SAPAP1
FUSION GENES

Other Information

Locus ID:

NCBI: 9229
MIM: 605445
HGNC: 2905
Ensembl: ENSG00000170579

Variants:

dbSNP: 9229
ClinVar: 9229
TCGA: ENSG00000170579
COSMIC: DLGAP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170579ENST00000315677O14490
ENSG00000170579ENST00000400145O14490
ENSG00000170579ENST00000400147O14490
ENSG00000170579ENST00000400149A8MYR7
ENSG00000170579ENST00000400150A8MXQ8
ENSG00000170579ENST00000400155O14490
ENSG00000170579ENST00000515196A0A0A0MTP4
ENSG00000170579ENST00000534970O14490
ENSG00000170579ENST00000539435O14490
ENSG00000170579ENST00000581527O14490
ENSG00000170579ENST00000581699O14490
ENSG00000170579ENST00000639615Q6IS01

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Glutamatergic synapseKEGGko04724
Glutamatergic synapseKEGGhsa04724
Neuronal SystemREACTOMER-HSA-112316
Protein-protein interactions at synapsesREACTOMER-HSA-6794362
Interactions of neurexins and neuroligins at synapsesREACTOMER-HSA-6794361

References

Pubmed IDYearTitleCitations
228899212013Genome-wide association study of obsessive-compulsive disorder.94
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
248212232015Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.84
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
210414482010Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity.31
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
241562662014Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease.12
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
229405462013Genetic analysis of the DLGAP1 gene as a candidate gene for schizophrenia.10
264851822016Recurrent major depression and right hippocampal volume: A bivariate linkage and association study.10

Citation

Dessen P

DLGAP1 (DLG associated protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57896/dlgap1