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DLGAP1 (DLG associated protein 1)

Identity

Alias_namesdiscs, large (Drosophila) homolog-associated protein 1
discs large homolog associated protein 1
Alias_symbol (synonym)GKAP
SAPAP1
DAP-1
Other aliasDAP-1-ALPHA
DAP-1-BETA
DAP1
DLGAP1A
DLGAP1B
HGNC (Hugo) DLGAP1
LocusID (NCBI) 9229
Atlas_Id 62519
Location 18p11.31  [Link to chromosome band 18p11]
Location_base_pair Starts at 3496032 and ends at 3845358 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTN4 (19q13.2) / DLGAP1 (18p11.31)CLK2 (1q22) / DLGAP1 (18p11.31)DLGAP1 (18p11.31) / ENOSF1 (18p11.32)
DLGAP1 (18p11.31) / GNL2 (1p34.3)DLGAP1 (18p11.31) / LGR4 (11p14.1)DLGAP1 (18p11.31) / RAB31 (18p11.22)
DLGAP1 (18p11.31) / TRAM2 (6p12.2)DLGAP1 (18p11.31) / UCKL1 (20q13.33)HIST1H4A (6p22.2) / DLGAP1 (18p11.31)
MAPKBP1 (15q15.1) / DLGAP1 (18p11.31)MTCL1 (18p11.22) / DLGAP1 (18p11.31)SGIP1 (1p31.3) / DLGAP1 (18p11.31)
ZNF451 (6p12.1) / DLGAP1 (18p11.31)DLGAP1 RAB31DLGAP1 ENOSF1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DLGAP1   2905
Cards
Entrez_Gene (NCBI)DLGAP1  9229  DLG associated protein 1
AliasesDAP-1; DAP-1-ALPHA; DAP-1-BETA; DAP1; 
DLGAP1A; DLGAP1B; GKAP; SAPAP1
GeneCards (Weizmann)DLGAP1
Ensembl hg19 (Hinxton)ENSG00000170579 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170579 [Gene_View]  chr18:3496032-3845358 [Contig_View]  DLGAP1 [Vega]
ICGC DataPortalENSG00000170579
TCGA cBioPortalDLGAP1
AceView (NCBI)DLGAP1
Genatlas (Paris)DLGAP1
WikiGenes9229
SOURCE (Princeton)DLGAP1
Genetics Home Reference (NIH)DLGAP1
Genomic and cartography
GoldenPath hg38 (UCSC)DLGAP1  -     chr18:3496032-3845358 -  18p11.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DLGAP1  -     18p11.31   [Description]    (hg19-Feb_2009)
EnsemblDLGAP1 - 18p11.31 [CytoView hg19]  DLGAP1 - 18p11.31 [CytoView hg38]
Mapping of homologs : NCBIDLGAP1 [Mapview hg19]  DLGAP1 [Mapview hg38]
OMIM605445   
Gene and transcription
Genbank (Entrez)AB000276 AB000277 AK095761 AK294717 AK294747
RefSeq transcript (Entrez)NM_001003809 NM_001242761 NM_001242762 NM_001242763 NM_001242764 NM_001242765 NM_001242766 NM_001308390 NM_004746
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DLGAP1
Cluster EST : UnigeneHs.673247 [ NCBI ]
CGAP (NCI)Hs.673247
Alternative Splicing GalleryENSG00000170579
Gene ExpressionDLGAP1 [ NCBI-GEO ]   DLGAP1 [ EBI - ARRAY_EXPRESS ]   DLGAP1 [ SEEK ]   DLGAP1 [ MEM ]
Gene Expression Viewer (FireBrowse)DLGAP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9229
GTEX Portal (Tissue expression)DLGAP1
Human Protein AtlasENSG00000170579-DLGAP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14490   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14490  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14490
Splice isoforms : SwissVarO14490
PhosPhoSitePlusO14490
Domains : Interpro (EBI)DLGAP1    SAPAP   
Domain families : Pfam (Sanger)GKAP (PF03359)   
Domain families : Pfam (NCBI)pfam03359   
Conserved Domain (NCBI)DLGAP1
DMDM Disease mutations9229
Blocks (Seattle)DLGAP1
SuperfamilyO14490
Human Protein Atlas [tissue]ENSG00000170579-DLGAP1 [tissue]
Peptide AtlasO14490
HPRD09260
IPIIPI00021941   IPI00216228   IPI00216229   IPI00788990   IPI00790084   IPI00789415   
Protein Interaction databases
DIP (DOE-UCLA)O14490
IntAct (EBI)O14490
FunCoupENSG00000170579
BioGRIDDLGAP1
STRING (EMBL)DLGAP1
ZODIACDLGAP1
Ontologies - Pathways
QuickGOO14490
Ontology : AmiGOprotein binding  cellular_component  plasma membrane  chemical synaptic transmission  postsynaptic density  cell junction  postsynaptic membrane  
Ontology : EGO-EBIprotein binding  cellular_component  plasma membrane  chemical synaptic transmission  postsynaptic density  cell junction  postsynaptic membrane  
Pathways : KEGGGlutamatergic synapse   
NDEx NetworkDLGAP1
Atlas of Cancer Signalling NetworkDLGAP1
Wikipedia pathwaysDLGAP1
Orthology - Evolution
OrthoDB9229
GeneTree (enSembl)ENSG00000170579
Phylogenetic Trees/Animal Genes : TreeFamDLGAP1
HOVERGENO14490
HOGENOMO14490
Homologs : HomoloGeneDLGAP1
Homology/Alignments : Family Browser (UCSC)DLGAP1
Gene fusions - Rearrangements
Fusion: TCGADLGAP1 RAB31
Fusion: TCGADLGAP1 ENOSF1
Fusion: Tumor Portal DLGAP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDLGAP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DLGAP1
dbVarDLGAP1
ClinVarDLGAP1
1000_GenomesDLGAP1 
Exome Variant ServerDLGAP1
ExAC (Exome Aggregation Consortium)ENSG00000170579
GNOMAD BrowserENSG00000170579
Genetic variants : HAPMAP9229
Genomic Variants (DGV)DLGAP1 [DGVbeta]
DECIPHERDLGAP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDLGAP1 
Mutations
ICGC Data PortalDLGAP1 
TCGA Data PortalDLGAP1 
Broad Tumor PortalDLGAP1
OASIS PortalDLGAP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDLGAP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDLGAP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DLGAP1
DgiDB (Drug Gene Interaction Database)DLGAP1
DoCM (Curated mutations)DLGAP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DLGAP1 (select a term)
intoGenDLGAP1
Cancer3DDLGAP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605445   
Orphanet
MedgenDLGAP1
Genetic Testing Registry DLGAP1
NextProtO14490 [Medical]
TSGene9229
GENETestsDLGAP1
Target ValidationDLGAP1
Huge Navigator DLGAP1 [HugePedia]
snp3D : Map Gene to Disease9229
BioCentury BCIQDLGAP1
ClinGenDLGAP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9229
Chemical/Pharm GKB GenePA27361
Clinical trialDLGAP1
Miscellaneous
canSAR (ICR)DLGAP1 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDLGAP1
EVEXDLGAP1
GoPubMedDLGAP1
iHOPDLGAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:44:44 CET 2017

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