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DLGAP4 (DLG associated protein 4)

Identity

Alias (NCBI)DAP-4
DAP4
DLP4
SAPAP-4
SAPAP4
HGNC (Hugo) DLGAP4
HGNC Alias symbDAP4
KIAA0964
SAPAP4
HGNC Previous namediscs, large (Drosophila) homolog-associated protein 4
 discs large homolog associated protein 4
LocusID (NCBI) 22839
Atlas_Id 54256
Location 20q11.23  [Link to chromosome band 20q11]
Location_base_pair Starts at 36461795 and ends at 36528633 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACOX3 (4p16.1) / DLGAP4 (20q11.23)ADNP (20q13.13) / DLGAP4 (20q11.23)DLGAP4 (20q11.23) / ADNP (20q13.13)
DLGAP4 (20q11.23) / BPI (20q11.23)DLGAP4 (20q11.23) / DLGAP4 (20q11.23)DLGAP4 (20q11.23) / SPSB3 (16p13.3)
DLGAP4 (20q11.23) / TUBD1 (17q23.1)DLGAP4 (20q11.23) / ZNF668 (16p11.2)HMCES (3q21.3) / DLGAP4 (20q11.23)
OSBPL2 (20q13.33) / DLGAP4 (20q11.23)POLR2J (7q22.1) / DLGAP4 (20q11.23)RAB3GAP2 (1q41) / DLGAP4 (20q11.23)
TGIF2 (20q11.23) / DLGAP4 (20q11.23)DLGAP4 20q11.23 / BPI 20q11.23DLGAP4 20q11.23 / TUBD1 17q23.1
OSBPL2 20q13.33 / DLGAP4 20q11.23TGIF2 20q11.23 / DLGAP4 20q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DLGAP4   24476
Cards
Entrez_Gene (NCBI)DLGAP4    DLG associated protein 4
AliasesDAP-4; DAP4; DLP4; SAPAP-4; 
SAPAP4
GeneCards (Weizmann)DLGAP4
Ensembl hg19 (Hinxton)ENSG00000080845 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000080845 [Gene_View]  ENSG00000080845 [Sequence]  chr20:36461795-36528633 [Contig_View]  DLGAP4 [Vega]
ICGC DataPortalENSG00000080845
TCGA cBioPortalDLGAP4
AceView (NCBI)DLGAP4
Genatlas (Paris)DLGAP4
SOURCE (Princeton)DLGAP4
Genetics Home Reference (NIH)DLGAP4
Genomic and cartography
GoldenPath hg38 (UCSC)DLGAP4  -     chr20:36461795-36528633 +  20q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DLGAP4  -     20q11.23   [Description]    (hg19-Feb_2009)
GoldenPathDLGAP4 - 20q11.23 [CytoView hg19]  DLGAP4 - 20q11.23 [CytoView hg38]
ImmunoBaseENSG00000080845
Genome Data Viewer NCBIDLGAP4 [Mapview hg19]  
OMIM616191   
Gene and transcription
Genbank (Entrez)AB023181 AF088030 AI984397 AK001681 AK024674
RefSeq transcript (Entrez)NM_001042486 NM_001365621 NM_001388257 NM_001388260 NM_001388262 NM_001388265 NM_001388268 NM_001388271 NM_001388274 NM_001388275 NM_001388277 NM_001388278 NM_014902 NM_183006
Consensus coding sequences : CCDS (NCBI)DLGAP4
Gene ExpressionDLGAP4 [ NCBI-GEO ]   DLGAP4 [ EBI - ARRAY_EXPRESS ]   DLGAP4 [ SEEK ]   DLGAP4 [ MEM ]
Gene Expression Viewer (FireBrowse)DLGAP4 [ Firebrowse - Broad ]
GenevisibleExpression of DLGAP4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22839
GTEX Portal (Tissue expression)DLGAP4
Human Protein AtlasENSG00000080845-DLGAP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2H0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2H0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2H0
PhosPhoSitePlusQ9Y2H0
Domains : Interpro (EBI)DLGAP4    SAPAP   
Domain families : Pfam (Sanger)GKAP (PF03359)   
Domain families : Pfam (NCBI)pfam03359   
Conserved Domain (NCBI)DLGAP4
SuperfamilyQ9Y2H0
AlphaFold pdb e-kbQ9Y2H0   
Human Protein Atlas [tissue]ENSG00000080845-DLGAP4 [tissue]
HPRD16826
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2H0
IntAct (EBI)Q9Y2H0
BioGRIDDLGAP4
STRING (EMBL)DLGAP4
ZODIACDLGAP4
Ontologies - Pathways
QuickGOQ9Y2H0
Ontology : AmiGOprotein binding  plasma membrane  signaling  neuromuscular junction  molecular adaptor activity  regulation of postsynaptic neurotransmitter receptor activity  glutamatergic synapse  cholinergic synapse  postsynaptic specialization  
Ontology : EGO-EBIprotein binding  plasma membrane  signaling  neuromuscular junction  molecular adaptor activity  regulation of postsynaptic neurotransmitter receptor activity  glutamatergic synapse  cholinergic synapse  postsynaptic specialization  
NDEx NetworkDLGAP4
Atlas of Cancer Signalling NetworkDLGAP4
Wikipedia pathwaysDLGAP4
Orthology - Evolution
OrthoDB22839
GeneTree (enSembl)ENSG00000080845
Phylogenetic Trees/Animal Genes : TreeFamDLGAP4
Homologs : HomoloGeneDLGAP4
Homology/Alignments : Family Browser (UCSC)DLGAP4
Gene fusions - Rearrangements
Fusion : MitelmanADNP/DLGAP4 [20q13.13/20q11.23]  
Fusion : MitelmanDLGAP4/ADNP [20q11.23/20q13.13]  
Fusion : MitelmanDLGAP4/BPI [20q11.23/20q11.23]  
Fusion : MitelmanDLGAP4/TUBD1 [20q11.23/17q23.1]  
Fusion : MitelmanOSBPL2/DLGAP4 [20q13.33/20q11.23]  
Fusion : MitelmanTGIF2/DLGAP4 [20q11.23/20q11.23]  
Fusion : QuiverDLGAP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDLGAP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DLGAP4
dbVarDLGAP4
ClinVarDLGAP4
MonarchDLGAP4
1000_GenomesDLGAP4 
Exome Variant ServerDLGAP4
GNOMAD BrowserENSG00000080845
Varsome BrowserDLGAP4
ACMGDLGAP4 variants
VarityQ9Y2H0
Genomic Variants (DGV)DLGAP4 [DGVbeta]
DECIPHERDLGAP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDLGAP4 
Mutations
ICGC Data PortalDLGAP4 
TCGA Data PortalDLGAP4 
Broad Tumor PortalDLGAP4
OASIS PortalDLGAP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDLGAP4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDLGAP4
Mutations and Diseases : HGMDDLGAP4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDLGAP4
DgiDB (Drug Gene Interaction Database)DLGAP4
DoCM (Curated mutations)DLGAP4
CIViC (Clinical Interpretations of Variants in Cancer)DLGAP4
Cancer3DDLGAP4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616191   
Orphanet
DisGeNETDLGAP4
MedgenDLGAP4
Genetic Testing Registry DLGAP4
NextProtQ9Y2H0 [Medical]
GENETestsDLGAP4
Target ValidationDLGAP4
Huge Navigator DLGAP4 [HugePedia]
ClinGenDLGAP4
Clinical trials, drugs, therapy
MyCancerGenomeDLGAP4
Protein Interactions : CTDDLGAP4
Pharm GKB GenePA134891458
PharosQ9Y2H0
Clinical trialDLGAP4
Miscellaneous
canSAR (ICR)DLGAP4
HarmonizomeDLGAP4
DataMed IndexDLGAP4
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDLGAP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:06:51 CEST 2021

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