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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

Donate (in Euros)

Donate (in US Dollars)

DLL3 (delta-like 3 (Drosophila))


Other namesSCDO1
HGNC (Hugo) DLL3
LocusID (NCBI) 10683
Location 19q13.2
Location_base_pair Starts at 39989557 and ends at 39999121 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)DLL3   2909
Entrez_Gene (NCBI)DLL3  10683  delta-like 3 (Drosophila)
GeneCards (Weizmann)DLL3
Ensembl hg19 (Hinxton)ENSG00000090932 [Gene_View]  chr19:39989557-39999121 [Contig_View]  DLL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000090932 [Gene_View]  chr19:39989557-39999121 [Contig_View]  DLL3 [Vega]
ICGC DataPortalENSG00000090932
AceView (NCBI)DLL3
Genatlas (Paris)DLL3
SOURCE (Princeton)DLL3
Genomic and cartography
GoldenPath hg19 (UCSC)DLL3  -     chr19:39989557-39999121 +  19q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DLL3  -     19q13.2   [Description]    (hg38-Dec_2013)
EnsemblDLL3 - 19q13.2 [CytoView hg19]  DLL3 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIDLL3 [Mapview hg19]  DLL3 [Mapview hg38]
OMIM277300   602768   
Gene and transcription
Genbank (Entrez)AA865362 AK075302 AK308460 BC000218 BQ420593
RefSeq transcript (Entrez)NM_016941 NM_203486
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_008256 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)DLL3
Cluster EST : UnigeneHs.127792 [ NCBI ]
CGAP (NCI)Hs.127792
Alternative Splicing : Fast-db (Paris)GSHG0014916
Alternative Splicing GalleryENSG00000090932
Gene ExpressionDLL3 [ NCBI-GEO ]     DLL3 [ SEEK ]   DLL3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYJ7 (Uniprot)
NextProtQ9NYJ7  [Medical]
With graphics : InterProQ9NYJ7
Splice isoforms : SwissVarQ9NYJ7 (Swissvar)
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)   
Domains : Interpro (EBI)EG-like_dom    EGF-like_CS    Growth_fac_rcpt_N_dom    Notch_ligand_N   
Related proteins : CluSTrQ9NYJ7
Domain families : Pfam (Sanger)EGF (PF00008)    hEGF (PF12661)    MNNL (PF07657)   
Domain families : Pfam (NCBI)pfam00008    pfam12661    pfam07657   
Domain families : Smart (EMBL)EGF (SM00181)  
DMDM Disease mutations10683
Blocks (Seattle)Q9NYJ7
Human Protein AtlasENSG00000090932
Peptide AtlasQ9NYJ7
IPIIPI00021010   IPI00409625   
Protein Interaction databases
IntAct (EBI)Q9NYJ7
Ontologies - Pathways
Ontology : AmiGOskeletal system development  somitogenesis  Notch binding  Notch signaling pathway  compartment pattern specification  integral component of membrane  paraxial mesoderm development  negative regulation of neurogenesis  
Ontology : EGO-EBIskeletal system development  somitogenesis  Notch binding  Notch signaling pathway  compartment pattern specification  integral component of membrane  paraxial mesoderm development  negative regulation of neurogenesis  
Pathways : KEGGNotch signaling pathway   
Protein Interaction DatabaseDLL3
DoCM (Curated mutations)DLL3
Wikipedia pathwaysDLL3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerDLL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DLL3
Exome Variant ServerDLL3
SNP (GeneSNP Utah)DLL3
Genetic variants : HAPMAPDLL3
Genomic Variants (DGV)DLL3 [DGVbeta]
ICGC Data PortalENSG00000090932 
Somatic Mutations in Cancer : COSMICDLL3 
CONAN: Copy Number AnalysisDLL3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)19:39989557-39999121
Mutations and Diseases : HGMDDLL3
OMIM277300    602768   
NextProtQ9NYJ7 [Medical]
Disease Genetic AssociationDLL3
Huge Navigator DLL3 [HugePedia]  DLL3 [HugeCancerGEM]
snp3D : Map Gene to Disease10683
DGIdb (Drug Gene Interaction db)DLL3
General knowledge
Homologs : HomoloGeneDLL3
Homology/Alignments : Family Browser (UCSC)DLL3
Phylogenetic Trees/Animal Genes : TreeFamDLL3
Chemical/Protein Interactions : CTD10683
Chemical/Pharm GKB GenePA27365
Clinical trialDLL3
Cancer Resource (Charite)ENSG00000090932
Other databases
PubMed18 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:13:18 CET 2015

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