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DLL3 (delta-like 3 (Drosophila))

Identity

Other namesSCDO1
HGNC (Hugo) DLL3
LocusID (NCBI) 10683
Location 19q13.2
Location_base_pair Starts at 39989557 and ends at 39999121 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DLL3   2909
Cards
Entrez_Gene (NCBI)DLL3  10683  delta-like 3 (Drosophila)
GeneCards (Weizmann)DLL3
Ensembl hg19 (Hinxton)ENSG00000090932 [Gene_View]  chr19:39989557-39999121 [Contig_View]  DLL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000090932 [Gene_View]  chr19:39989557-39999121 [Contig_View]  DLL3 [Vega]
ICGC DataPortalENSG00000090932
cBioPortalDLL3
AceView (NCBI)DLL3
Genatlas (Paris)DLL3
WikiGenes10683
SOURCE (Princeton)DLL3
Genomic and cartography
GoldenPath hg19 (UCSC)DLL3  -     chr19:39989557-39999121 +  19q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DLL3  -     19q13.2   [Description]    (hg38-Dec_2013)
EnsemblDLL3 - 19q13.2 [CytoView hg19]  DLL3 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIDLL3 [Mapview hg19]  DLL3 [Mapview hg38]
OMIM277300   602768   
Gene and transcription
Genbank (Entrez)AA865362 AK075302 AK308460 BC000218 BQ420593
RefSeq transcript (Entrez)NM_016941 NM_203486
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_008256 NT_011109 NW_001838496 NW_004929415
Consensus coding sequences : CCDS (NCBI)DLL3
Cluster EST : UnigeneHs.127792 [ NCBI ]
CGAP (NCI)Hs.127792
Alternative Splicing : Fast-db (Paris)GSHG0014916
Alternative Splicing GalleryENSG00000090932
Gene ExpressionDLL3 [ NCBI-GEO ]     DLL3 [ SEEK ]   DLL3 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYJ7 (Uniprot)
NextProtQ9NYJ7  [Medical]
With graphics : InterProQ9NYJ7
Splice isoforms : SwissVarQ9NYJ7 (Swissvar)
Domaine pattern : Prosite (Expaxy)EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)   
Domains : Interpro (EBI)EG-like_dom    EGF-like_CS    Growth_fac_rcpt_N_dom    Notch_ligand_N   
Related proteins : CluSTrQ9NYJ7
Domain families : Pfam (Sanger)EGF (PF00008)    hEGF (PF12661)    MNNL (PF07657)   
Domain families : Pfam (NCBI)pfam00008    pfam12661    pfam07657   
Domain families : Smart (EMBL)EGF (SM00181)  
DMDM Disease mutations10683
Blocks (Seattle)Q9NYJ7
Human Protein AtlasENSG00000090932
Peptide AtlasQ9NYJ7
HPRD04140
IPIIPI00021010   IPI00409625   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYJ7
IntAct (EBI)Q9NYJ7
FunCoupENSG00000090932
BioGRIDDLL3
IntegromeDBDLL3
STRING (EMBL)DLL3
Ontologies - Pathways
QuickGOQ9NYJ7
Ontology : AmiGOskeletal system development  somitogenesis  Notch binding  Notch signaling pathway  compartment pattern specification  integral component of membrane  paraxial mesoderm development  negative regulation of neurogenesis  
Ontology : EGO-EBIskeletal system development  somitogenesis  Notch binding  Notch signaling pathway  compartment pattern specification  integral component of membrane  paraxial mesoderm development  negative regulation of neurogenesis  
Pathways : KEGGNotch signaling pathway   
Protein Interaction DatabaseDLL3
DoCM (Curated mutations)DLL3
Wikipedia pathwaysDLL3
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerDLL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DLL3
dbVarDLL3
ClinVarDLL3
1000_GenomesDLL3 
Exome Variant ServerDLL3
SNP (GeneSNP Utah)DLL3
SNP : HGBaseDLL3
Genetic variants : HAPMAPDLL3
Genomic VariantsDLL3  DLL3 [DGVbeta]
Mutations
ICGC Data PortalENSG00000090932 
Somatic Mutations in Cancer : COSMICDLL3 
CONAN: Copy Number AnalysisDLL3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:39989557-39999121
Mutations and Diseases : HGMDDLL3
OMIM277300    602768   
MedgenDLL3
NextProtQ9NYJ7 [Medical]
GENETestsDLL3
Disease Genetic AssociationDLL3
Huge Navigator DLL3 [HugePedia]  DLL3 [HugeCancerGEM]
snp3D : Map Gene to Disease10683
DGIdb (Drug Gene Interaction db)DLL3
General knowledge
Homologs : HomoloGeneDLL3
Homology/Alignments : Family Browser (UCSC)DLL3
Phylogenetic Trees/Animal Genes : TreeFamDLL3
Chemical/Protein Interactions : CTD10683
Chemical/Pharm GKB GenePA27365
Clinical trialDLL3
Cancer Resource (Charite)ENSG00000090932
Other databases
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
CoreMineDLL3
GoPubMedDLL3
iHOPDLL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 21:13:12 CET 2014

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