DLL4 (delta-like 4 (Drosophila))

Identity

Other names	MGC126344
	hdelta2
HGNC	DLL4
Location	15q14
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DLL4   2910
Entrez_Gene	DLL4  54567  delta-like 4 (Drosophila)
	Cards
GeneCards	DLL4
Ensembl	DLL4 [Search_View]   ENSG00000128917 [Gene_View]
Genatlas	DLL4
GeneLynx	DLL4
eGenome	DLL4
euGene	54567
	Genomic and cartography
GoldenPath	DLL4  -  15q14   chr15:39008839-39018529 +  15q15.1   [Description]    (hg18-March_2006)
Ensembl	DLL4 - 15q15.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DLL4
	Gene and transcription
Genbank	AB036931 [ ENTREZ ]
Genbank	AB043894 [ ENTREZ ]
Genbank	AF253468 [ ENTREZ ]
Genbank	AF279305 [ ENTREZ ]
Genbank	AK313831 [ ENTREZ ]
RefSeq	NM_019074 [ SRS ]    NM_019074 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838214 [ SRS ]    NW_001838214 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	DLL4 AceView - NCBI
Unigene	Hs.511076 [ SRS ]    Hs.511076 [ NCBI ]     HS511076 [ spliceNest ]
Fast-db	2374 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9NR61 [ SRS]    Q9NR61 [ EXPASY ]     Q9NR61 [ INTERPRO ]     Q9NR61 [ UNIPROT ]
Prosite	PS00010 ASX_HYDROXYL [ SRS ]    PS00010 ASX_HYDROXYL [ Expasy ]
Prosite	PS51051 DSL [ SRS ]    PS51051 DSL [ Expasy ]
Prosite	PS00022 EGF_1 [ SRS ]    PS00022 EGF_1 [ Expasy ]
Prosite	PS01186 EGF_2 [ SRS ]    PS01186 EGF_2 [ Expasy ]
Prosite	PS50026 EGF_3 [ SRS ]    PS50026 EGF_3 [ Expasy ]
Interpro	IPR001774 DSL [ SRS ]    IPR001774 DSL [ EBI ]
Interpro	IPR006210 EGF [ SRS ]    IPR006210 EGF [ EBI ]
Interpro	IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ SRS ]    IPR000152 EGF-type_Asp/Asn_hydroxyl_CS [ EBI ]
Interpro	IPR001438 EGF_2 [ SRS ]    IPR001438 EGF_2 [ EBI ]
Interpro	IPR000742 EGF_3 [ SRS ]    IPR000742 EGF_3 [ EBI ]
Interpro	IPR001881 EGF_Ca_bd [ SRS ]    IPR001881 EGF_Ca_bd [ EBI ]
Interpro	IPR013111 EGF_extracell [ SRS ]    IPR013111 EGF_extracell [ EBI ]
Interpro	IPR006209 EGF_like [ SRS ]    IPR006209 EGF_like [ EBI ]
Interpro	IPR013032 EGF_like_reg_CS [ SRS ]    IPR013032 EGF_like_reg_CS [ EBI ]
Interpro	IPR011651 Notch_ligand_N [ SRS ]    IPR011651 Notch_ligand_N [ EBI ]
CluSTr	Q9NR61
Pfam	PF01414 DSL [ SRS ]    PF01414 DSL [ Sanger ]    pfam01414 [ NCBI-CDD ]
Pfam	PF00008 EGF [ SRS ]    PF00008 EGF [ Sanger ]    pfam00008 [ NCBI-CDD ]
Pfam	PF07974 EGF_2 [ SRS ]    PF07974 EGF_2 [ Sanger ]    pfam07974 [ NCBI-CDD ]
Pfam	PF07657 MNNL [ SRS ]    PF07657 MNNL [ Sanger ]    pfam07657 [ NCBI-CDD ]
Smart	SM00051 DSL [EMBL]
Smart	SM00181 EGF [EMBL]
Smart	SM00179 EGF_CA [EMBL]
Blocks	Q9NR61
HPRD	05540
	Protein Interaction databases
DIP	Q9NR61
IntAct	Q9NR61
	Polymorphism : SNP, mutations, diseases
OMIM	605185    [ map ]
GENECLINICS	605185
SNP	DLL4 [dbSNP-NCBI]
SNP	NM_019074 [SNP-NCI]
SNP	DLL4 [GeneSNPs - Utah]  DLL4] [HGBASE - SRS]
HAPMAP	DLL4 [HAPMAP]
COSMIC	DLL4 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DLL4
	General knowledge
Family Browser	DLL4 [UCSC Family Browser]
SOURCE	NM_019074
SMD	Hs.511076
SAGE	Hs.511076
GO	angiogenesis [Amigo]  angiogenesis
GO	Notch binding [Amigo]  Notch binding
GO	calcium ion binding [Amigo]  calcium ion binding
GO	protein binding [Amigo]  protein binding
GO	signal transduction [Amigo]  signal transduction
GO	Notch signaling pathway [Amigo]  Notch signaling pathway
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	blood circulation [Amigo]  blood circulation
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	cell differentiation [Amigo]  cell differentiation
KEGG	Notch signaling pathway
PubGene	DLL4
TreeFam	DLL4
CTD	54567 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DLL4 Related clones (RZPD - Berlin)
	PubMed
PubMed	26 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:08:09 2008