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DLX3 (distal-less homeobox 3)

Identity

Alias_namesdistal-less homeo box 3
Other aliasAI4
TDO
HGNC (Hugo) DLX3
LocusID (NCBI) 1747
Atlas_Id 49723
Location 17q21.33  [Link to chromosome band 17q21]
Location_base_pair Starts at 49990005 and ends at 49995224 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DLX3   2916
Cards
Entrez_Gene (NCBI)DLX3  1747  distal-less homeobox 3
AliasesAI4; TDO
GeneCards (Weizmann)DLX3
Ensembl hg19 (Hinxton)ENSG00000064195 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064195 [Gene_View]  chr17:49990005-49995224 [Contig_View]  DLX3 [Vega]
ICGC DataPortalENSG00000064195
TCGA cBioPortalDLX3
AceView (NCBI)DLX3
Genatlas (Paris)DLX3
WikiGenes1747
SOURCE (Princeton)DLX3
Genetics Home Reference (NIH)DLX3
Genomic and cartography
GoldenPath hg38 (UCSC)DLX3  -     chr17:49990005-49995224 -  17q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DLX3  -     17q21.33   [Description]    (hg19-Feb_2009)
EnsemblDLX3 - 17q21.33 [CytoView hg19]  DLX3 - 17q21.33 [CytoView hg38]
Mapping of homologs : NCBIDLX3 [Mapview hg19]  DLX3 [Mapview hg38]
OMIM104510   190320   600525   
Gene and transcription
Genbank (Entrez)AA604314 AK075167 AK313257 BC012361 BC028970
RefSeq transcript (Entrez)NM_005220
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DLX3
Cluster EST : UnigeneHs.134194 [ NCBI ]
CGAP (NCI)Hs.134194
Alternative Splicing GalleryENSG00000064195
Gene ExpressionDLX3 [ NCBI-GEO ]   DLX3 [ EBI - ARRAY_EXPRESS ]   DLX3 [ SEEK ]   DLX3 [ MEM ]
Gene Expression Viewer (FireBrowse)DLX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1747
GTEX Portal (Tissue expression)DLX3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60479   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60479  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60479
Splice isoforms : SwissVarO60479
PhosPhoSitePlusO60479
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Distal-less_N    Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    HTH_motif   
Domain families : Pfam (Sanger)DLL_N (PF12413)    Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam12413    pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)DLX3
DMDM Disease mutations1747
Blocks (Seattle)DLX3
PDB (SRS)4XRS   
PDB (PDBSum)4XRS   
PDB (IMB)4XRS   
PDB (RSDB)4XRS   
Structural Biology KnowledgeBase4XRS   
SCOP (Structural Classification of Proteins)4XRS   
CATH (Classification of proteins structures)4XRS   
SuperfamilyO60479
Human Protein AtlasENSG00000064195
Peptide AtlasO60479
HPRD02752
IPIIPI00029716   IPI01021511   
Protein Interaction databases
DIP (DOE-UCLA)O60479
IntAct (EBI)O60479
FunCoupENSG00000064195
BioGRIDDLX3
STRING (EMBL)DLX3
ZODIACDLX3
Ontologies - Pathways
QuickGOO60479
Ontology : AmiGOtranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blood vessel development  placenta development  chromatin binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription from RNA polymerase II promoter  odontogenesis of dentin-containing tooth  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  odontoblast differentiation  
Ontology : EGO-EBItranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  blood vessel development  placenta development  chromatin binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription from RNA polymerase II promoter  odontogenesis of dentin-containing tooth  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  odontoblast differentiation  
NDEx NetworkDLX3
Atlas of Cancer Signalling NetworkDLX3
Wikipedia pathwaysDLX3
Orthology - Evolution
OrthoDB1747
GeneTree (enSembl)ENSG00000064195
Phylogenetic Trees/Animal Genes : TreeFamDLX3
HOVERGENO60479
HOGENOMO60479
Homologs : HomoloGeneDLX3
Homology/Alignments : Family Browser (UCSC)DLX3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDLX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DLX3
dbVarDLX3
ClinVarDLX3
1000_GenomesDLX3 
Exome Variant ServerDLX3
ExAC (Exome Aggregation Consortium)DLX3 (select the gene name)
Genetic variants : HAPMAP1747
Genomic Variants (DGV)DLX3 [DGVbeta]
DECIPHERDLX3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDLX3 
Mutations
ICGC Data PortalDLX3 
TCGA Data PortalDLX3 
Broad Tumor PortalDLX3
OASIS PortalDLX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDLX3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDLX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DLX3
DgiDB (Drug Gene Interaction Database)DLX3
DoCM (Curated mutations)DLX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DLX3 (select a term)
intoGenDLX3
Cancer3DDLX3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104510    190320    600525   
Orphanet2971    14607   
MedgenDLX3
Genetic Testing Registry DLX3
NextProtO60479 [Medical]
TSGene1747
GENETestsDLX3
Target ValidationDLX3
Huge Navigator DLX3 [HugePedia]
snp3D : Map Gene to Disease1747
BioCentury BCIQDLX3
ClinGenDLX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1747
Chemical/Pharm GKB GenePA27371
Clinical trialDLX3
Miscellaneous
canSAR (ICR)DLX3 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDLX3
EVEXDLX3
GoPubMedDLX3
iHOPDLX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:31:19 CEST 2017

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