Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DMRT2 (doublesex and mab-3 related transcription factor 2)

Identity

Other alias-
HGNC (Hugo) DMRT2
LocusID (NCBI) 10655
Atlas_Id 53790
Location 9p24.3  [Link to chromosome band 9p24]
Location_base_pair Starts at 1050354 and ends at 1057554 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZMYM2 (13q12.11) / DMRT2 (9p24.3)ZMYM2 13q12.11 / DMRT2 9p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DMRT2   2935
Cards
Entrez_Gene (NCBI)DMRT2  10655  doublesex and mab-3 related transcription factor 2
Aliases
GeneCards (Weizmann)DMRT2
Ensembl hg19 (Hinxton)ENSG00000173253 [Gene_View]  chr9:1050354-1057554 [Contig_View]  DMRT2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173253 [Gene_View]  chr9:1050354-1057554 [Contig_View]  DMRT2 [Vega]
ICGC DataPortalENSG00000173253
TCGA cBioPortalDMRT2
AceView (NCBI)DMRT2
Genatlas (Paris)DMRT2
WikiGenes10655
SOURCE (Princeton)DMRT2
Genetics Home Reference (NIH)DMRT2
Genomic and cartography
GoldenPath hg19 (UCSC)DMRT2  -     chr9:1050354-1057554 +  9p24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DMRT2  -     9p24.3   [Description]    (hg38-Dec_2013)
EnsemblDMRT2 - 9p24.3 [CytoView hg19]  DMRT2 - 9p24.3 [CytoView hg38]
Mapping of homologs : NCBIDMRT2 [Mapview hg19]  DMRT2 [Mapview hg38]
OMIM604935   
Gene and transcription
Genbank (Entrez)AA771859 AF130729 AF284221 AF284222 AF284223
RefSeq transcript (Entrez)NM_001130865 NM_006557 NM_181872
RefSeq genomic (Entrez)NC_000009 NC_018920 NG_017051 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)DMRT2
Cluster EST : UnigeneHs.59506 [ NCBI ]
CGAP (NCI)Hs.59506
Alternative Splicing GalleryENSG00000173253
Gene ExpressionDMRT2 [ NCBI-GEO ]   DMRT2 [ EBI - ARRAY_EXPRESS ]   DMRT2 [ SEEK ]   DMRT2 [ MEM ]
Gene Expression Viewer (FireBrowse)DMRT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10655
GTEX Portal (Tissue expression)DMRT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5R5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5R5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5R5
Splice isoforms : SwissVarQ9Y5R5
PhosPhoSitePlusQ9Y5R5
Domaine pattern : Prosite (Expaxy)DM_1 (PS40000)    DM_2 (PS50809)   
Domains : Interpro (EBI)DM_DNA-bd    DMRT/dsx/mab-3   
Domain families : Pfam (Sanger)DM (PF00751)   
Domain families : Pfam (NCBI)pfam00751   
Domain families : Smart (EMBL)DM (SM00301)  
Conserved Domain (NCBI)DMRT2
DMDM Disease mutations10655
Blocks (Seattle)DMRT2
SuperfamilyQ9Y5R5
Human Protein AtlasENSG00000173253
Peptide AtlasQ9Y5R5
HPRD16079
IPIIPI00334605   IPI00001732   IPI01018035   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5R5
IntAct (EBI)Q9Y5R5
FunCoupENSG00000173253
BioGRIDDMRT2
STRING (EMBL)DMRT2
ZODIACDMRT2
Ontologies - Pathways
QuickGOQ9Y5R5
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  core promoter proximal region sequence-specific DNA binding  molecular_function  transcription factor activity, sequence-specific DNA binding  cellular_component  nucleus  transcription, DNA-templated  sex differentiation  biological_process  regulation of somitogenesis  protein homodimerization activity  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  embryonic skeletal system development  positive regulation of myotome development  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  core promoter proximal region sequence-specific DNA binding  molecular_function  transcription factor activity, sequence-specific DNA binding  cellular_component  nucleus  transcription, DNA-templated  sex differentiation  biological_process  regulation of somitogenesis  protein homodimerization activity  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  embryonic skeletal system development  positive regulation of myotome development  
NDEx NetworkDMRT2
Atlas of Cancer Signalling NetworkDMRT2
Wikipedia pathwaysDMRT2
Orthology - Evolution
OrthoDB10655
GeneTree (enSembl)ENSG00000173253
Phylogenetic Trees/Animal Genes : TreeFamDMRT2
HOVERGENQ9Y5R5
HOGENOMQ9Y5R5
Homologs : HomoloGeneDMRT2
Homology/Alignments : Family Browser (UCSC)DMRT2
Gene fusions - Rearrangements
Fusion : MitelmanZMYM2/DMRT2 [13q12.11/9p24.3]  [t(9;13)(p24;q12)]  
Fusion: TCGAZMYM2 13q12.11 DMRT2 9p24.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDMRT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DMRT2
dbVarDMRT2
ClinVarDMRT2
1000_GenomesDMRT2 
Exome Variant ServerDMRT2
ExAC (Exome Aggregation Consortium)DMRT2 (select the gene name)
Genetic variants : HAPMAP10655
Genomic Variants (DGV)DMRT2 [DGVbeta]
DECIPHER (Syndromes)9:1050354-1057554  ENSG00000173253
CONAN: Copy Number AnalysisDMRT2 
Mutations
ICGC Data PortalDMRT2 
TCGA Data PortalDMRT2 
Broad Tumor PortalDMRT2
OASIS PortalDMRT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDMRT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDMRT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DMRT2
DgiDB (Drug Gene Interaction Database)DMRT2
DoCM (Curated mutations)DMRT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DMRT2 (select a term)
intoGenDMRT2
Cancer3DDMRT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604935   
Orphanet
MedgenDMRT2
Genetic Testing Registry DMRT2
NextProtQ9Y5R5 [Medical]
TSGene10655
GENETestsDMRT2
Huge Navigator DMRT2 [HugePedia]
snp3D : Map Gene to Disease10655
BioCentury BCIQDMRT2
ClinGenDMRT2 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10655
Chemical/Pharm GKB GenePA27382
Clinical trialDMRT2
Miscellaneous
canSAR (ICR)DMRT2 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDMRT2
EVEXDMRT2
GoPubMedDMRT2
iHOPDMRT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:59:02 CEST 2017

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