Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DNA2 (DNA replication helicase 2 homolog (yeast))

Identity

Other namesDNA2L
hDNA2
HGNC (Hugo) DNA2
LocusID (NCBI) 1763
Location 10q21.3
Location_base_pair Starts at 70173821 and ends at 70231730 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DNA2   2939
Entrez_Gene (NCBI)DNA2  1763  DNA replication helicase 2 homolog (yeast)
Cards
GeneCards (Weizmann)DNA2
Ensembl (Hinxton)ENSG00000138346 [Gene_View]  chr10:70173821-70231730 [Contig_View]  DNA2 [Vega]
AceView (NCBI)DNA2
Genatlas (Paris)DNA2
SOURCE (Stanford)NM_001080449
Genomic and cartography
GoldenPath (UCSC)DNA2  -  10q21.3   chr10:70173821-70231730 -  10q21.3   [Description]    (hg19-Feb_2009)
EnsemblDNA2 - 10q21.3 [CytoView]
Mapping of homologs : NCBIDNA2 [Mapview]
OMIM601810   
Gene and transcription
Genbank (Entrez)AK307939 AK308333 AK308358 BC017003 BC028188
RefSeq transcript (SRS)NM_001080449
RefSeq transcript (Entrez)NM_001080449
RefSeq genomic (SRS)AC_000142 NC_000010 NC_018921 NT_030059 NW_001837986 NW_004078068
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NT_030059 NW_001837986 NW_004078068
Consensus coding sequences : CCDS (NCBI)DNA2
Cluster EST : UnigeneHs.532446 [ SRS ] Hs.532446 [ NCBI ]
CGAP (NCI)Hs.532446
Alternative Splicing : Fast-db (Paris)GSHG0004126
Alternative Splicing GalleryENSG00000138346
Gene ExpressionDNA2 [ NCBI-GEO ]   DNA2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51530 (SRS) P51530 (Uniprot)
NextProtP51530
With graphics : InterProP51530
Splice isoforms : SwissVarP51530(Swissvar)
Domains : Interpro (SRS)Dna2    DNA_replication_fac_Dna2_N   
Domains : Interpro (EBI)Dna2    DNA_replication_fac_Dna2_N   
Related proteins : CluSTrP51530
Domain families : Pfam (SRS)Dna2 (PF08696)   
Domain families : Pfam (Sanger)Dna2 (PF08696)   
Domain families : Pfam (NCBI)pfam08696   
DMDM1763
Blocks (Seattle)P51530
Human Protein AtlasENSG00000138346
IPIIPI00816801   IPI00816670   IPI01022035   IPI01022599   IPI00216142   IPI01022609   
Protein Interaction databases
DIP (DOE-UCLA)P51530
IntAct (EBI)P51530
FunCoupENSG00000138346
REACTOMEDNA2
Protein Interaction Database1763
BioGRIDDNA2
InParanoidP51530
Interologous Interaction database P51530
IntegromeDBDNA2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DNA2
SNP (GeneSNP Utah)DNA2
SNP : HGBaseDNA2
Genetic variants : HAPMAPDNA2
Somatic Mutations in Cancer : COSMICDNA2 
CONAN: Copy Number AnalysisDNA2 
Mutations and Diseases : HGMDDNA2
OMIM601810   
GENETests601810   
Disease Genetic AssociationDNA2
Huge Navigator DNA2 [HugePedia]  DNA2 [HugeCancerGEM]
Genomic VariantsDNA2  DNA2 [DGVbeta]
snp3D : Map Gene to Disease1763
General knowledge
Homologs : HomoloGeneDNA2
Homology/Alignments : Family Browser (UCSC)DNA2
Phylogenetic Trees/Animal Genes : TreeFamDNA2
Catalytic activity : Enzyme3.1.-.- [ Enzyme-Expasy ]   3.1.-.- [ Enzyme-SRS ]   3.1.-.- [ IntEnz-EBI ]   3.1.-.- [ BRENDA ]   3.1.-.- [ KEGG ]   
Chemical/Protein Interactions : CTD1763
Chemical/Pharm GKB GenePA162383798
Clinical trialDNA2
Cancer Resource (Charite)ENSG00000138346
Ontology : AmiGODNA replication checkpoint  S phase of mitotic cell cycle  mitotic cell cycle  telomere maintenance via recombination  telomere maintenance  DNA double-strand break processing  DNA binding  DNA helicase activity  DNA helicase activity  helicase activity  nuclease activity  protein binding  ATP binding  nucleus  nucleoplasm  gamma DNA polymerase complex  ATP catabolic process  DNA replication  mitochondrial DNA replication  DNA strand elongation involved in DNA replication  base-excision repair  ATPase activity  site-specific endodeoxyribonuclease activity, specific for altered base  5'-flap endonuclease activity  telomere maintenance via semi-conservative replication  DNA duplex unwinding  DNA replication, Okazaki fragment processing  mitochondrial nucleoid  DNA replication, removal of RNA primer  5'-3' DNA helicase activity  single-stranded DNA-dependent ATPase activity  mitochondrial DNA repair  positive regulation of DNA replication  metal ion binding  4 iron, 4 sulfur cluster binding  
Ontology : EGO-EBIDNA replication checkpoint  S phase of mitotic cell cycle  mitotic cell cycle  telomere maintenance via recombination  telomere maintenance  DNA double-strand break processing  DNA binding  DNA helicase activity  DNA helicase activity  helicase activity  nuclease activity  protein binding  ATP binding  nucleus  nucleoplasm  gamma DNA polymerase complex  ATP catabolic process  DNA replication  mitochondrial DNA replication  DNA strand elongation involved in DNA replication  base-excision repair  ATPase activity  site-specific endodeoxyribonuclease activity, specific for altered base  5'-flap endonuclease activity  telomere maintenance via semi-conservative replication  DNA duplex unwinding  DNA replication, Okazaki fragment processing  mitochondrial nucleoid  DNA replication, removal of RNA primer  5'-3' DNA helicase activity  single-stranded DNA-dependent ATPase activity  mitochondrial DNA repair  positive regulation of DNA replication  metal ion binding  4 iron, 4 sulfur cluster binding  
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
PubGeneDNA2
iHOPDNA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:36:33 CEST 2013

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