| Nomenclature | | HGNC (Hugo) | DNA2 2939 |
| Entrez_Gene (NCBI) | DNA2 1763 DNA replication helicase 2 homolog (yeast) |
| Cards | | GeneCards (Weizmann) | DNA2 |
| Ensembl (Hinxton) | ENSG00000138346 [Gene_View] chr10:70173821-70231730 [Contig_View] DNA2 [Vega] |
| AceView (NCBI) | DNA2 |
| Genatlas (Paris) | DNA2 |
| SOURCE (Stanford) | NM_001080449 |
| Genomic and cartography | | GoldenPath (UCSC) | DNA2 - 10q21.3 chr10:70173821-70231730 - 10q21.3 [Description] (hg19-Feb_2009) |
| Ensembl | DNA2 - 10q21.3 [CytoView] |
| Mapping of homologs : NCBI | DNA2 [Mapview] |
| OMIM | 601810 |
| Gene and transcription |
| Genbank (Entrez) | AK307939 AK308333 AK308358 BC017003 BC028188 |
| RefSeq transcript (SRS) | NM_001080449 |
| RefSeq transcript (Entrez) | NM_001080449 |
| RefSeq genomic (SRS) | AC_000142 NC_000010 NC_018921 NT_030059 NW_001837986 NW_004078068 |
| RefSeq genomic (Entrez) | AC_000142 NC_000010 NC_018921 NT_030059 NW_001837986 NW_004078068 |
| Consensus coding sequences : CCDS (NCBI) | DNA2 |
| Cluster EST : Unigene | Hs.532446 [ SRS ] Hs.532446 [ NCBI ] |
| CGAP (NCI) | Hs.532446 |
| Alternative Splicing : Fast-db (Paris) | GSHG0004126 |
| Alternative Splicing Gallery | ENSG00000138346 |
| Gene Expression | DNA2 [ NCBI-GEO ] DNA2 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P51530 (SRS) P51530 (Uniprot) |
| NextProt | P51530 |
| With graphics : InterPro | P51530 |
| Splice isoforms : SwissVar | P51530(Swissvar) |
| Domains : Interpro (SRS) | Dna2 DNA_replication_fac_Dna2_N |
| Domains : Interpro (EBI) | Dna2 DNA_replication_fac_Dna2_N |
| Related proteins : CluSTr | P51530 |
| Domain families : Pfam (SRS) | Dna2 (PF08696) |
| Domain families : Pfam (Sanger) | Dna2 (PF08696) |
| Domain families : Pfam (NCBI) | pfam08696 |
| DMDM | 1763 |
| Blocks (Seattle) | P51530 |
| Human Protein Atlas | ENSG00000138346 |
| IPI | IPI00816801 IPI00816670 IPI01022035 IPI01022599 IPI00216142 IPI01022609 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P51530 |
| IntAct (EBI) | P51530 |
| FunCoup | ENSG00000138346 |
| REACTOME | DNA2 |
| Protein Interaction Database | 1763 |
| BioGRID | DNA2 |
| InParanoid | P51530 |
| Interologous Interaction database | P51530 |
| IntegromeDB | DNA2 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | DNA2 |
| SNP (GeneSNP Utah) | DNA2 |
| SNP : HGBase | DNA2 |
| Genetic variants : HAPMAP | DNA2 |
| Somatic Mutations in Cancer : COSMIC | DNA2 |
| CONAN: Copy Number Analysis | DNA2 |
| Mutations and Diseases : HGMD | DNA2 |
| OMIM | 601810 |
| GENETests | 601810 |
| Disease Genetic Association | DNA2 |
| Huge Navigator |
DNA2 [HugePedia] DNA2 [HugeCancerGEM] |
| Genomic Variants | DNA2 DNA2 [DGVbeta] |
| snp3D : Map Gene to Disease | 1763 |
| General knowledge |
|---|
| Homologs : HomoloGene | DNA2 |
| Homology/Alignments : Family Browser (UCSC) | DNA2 |
| Phylogenetic Trees/Animal Genes : TreeFam | DNA2 |
| Catalytic activity : Enzyme | 3.1.-.- [ Enzyme-Expasy ] 3.1.-.- [ Enzyme-SRS ] 3.1.-.- [ IntEnz-EBI ] 3.1.-.- [ BRENDA ] 3.1.-.- [ KEGG ] |
| Chemical/Protein Interactions : CTD | 1763 |
| Chemical/Pharm GKB Gene | PA162383798 |
| Clinical trial | DNA2 |
| Cancer Resource (Charite) | ENSG00000138346 |
| Ontology : AmiGO | DNA replication checkpoint S phase of mitotic cell cycle mitotic cell cycle telomere maintenance via recombination telomere maintenance DNA double-strand break processing DNA binding DNA helicase activity DNA helicase activity helicase activity nuclease activity protein binding ATP binding nucleus nucleoplasm gamma DNA polymerase complex ATP catabolic process DNA replication mitochondrial DNA replication DNA strand elongation involved in DNA replication base-excision repair ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity telomere maintenance via semi-conservative replication DNA duplex unwinding DNA replication, Okazaki fragment processing mitochondrial nucleoid DNA replication, removal of RNA primer 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity mitochondrial DNA repair positive regulation of DNA replication metal ion binding 4 iron, 4 sulfur cluster binding |
| Ontology : EGO-EBI | DNA replication checkpoint S phase of mitotic cell cycle mitotic cell cycle telomere maintenance via recombination telomere maintenance DNA double-strand break processing DNA binding DNA helicase activity DNA helicase activity helicase activity nuclease activity protein binding ATP binding nucleus nucleoplasm gamma DNA polymerase complex ATP catabolic process DNA replication mitochondrial DNA replication DNA strand elongation involved in DNA replication base-excision repair ATPase activity site-specific endodeoxyribonuclease activity, specific for altered base 5'-flap endonuclease activity telomere maintenance via semi-conservative replication DNA duplex unwinding DNA replication, Okazaki fragment processing mitochondrial nucleoid DNA replication, removal of RNA primer 5'-3' DNA helicase activity single-stranded DNA-dependent ATPase activity mitochondrial DNA repair positive regulation of DNA replication metal ion binding 4 iron, 4 sulfur cluster binding |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 20 Pubmed reference(s) in Entrez |
| PubGene | DNA2 |
| iHOP | DNA2 |