Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DNAH11 (dynein axonemal heavy chain 11)

Identity

Alias_namesdynein, axonemal, heavy polypeptide 11
Alias_symbol (synonym)Dnahc11
DPL11
CILD7
DNAHC11
DNAHBL
DNHBL
Other alias
HGNC (Hugo) DNAH11
LocusID (NCBI) 8701
Atlas_Id 62546
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 21543215 and ends at 21901568 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAH11 (7p15.3) / CLSTN1 (1p36.22)DNAH11 (7p15.3) / MICAL2 (11p15.3)KLHL7 (7p15.3) / DNAH11 (7p15.3)
TRA2A (7p15.3) / DNAH11 (7p15.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNAH11   2942
Cards
Entrez_Gene (NCBI)DNAH11  8701  dynein axonemal heavy chain 11
AliasesCILD7; DNAHBL; DNAHC11; DNHBL; 
DPL11
GeneCards (Weizmann)DNAH11
Ensembl hg19 (Hinxton)ENSG00000105877 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105877 [Gene_View]  chr7:21543215-21901568 [Contig_View]  DNAH11 [Vega]
ICGC DataPortalENSG00000105877
TCGA cBioPortalDNAH11
AceView (NCBI)DNAH11
Genatlas (Paris)DNAH11
WikiGenes8701
SOURCE (Princeton)DNAH11
Genetics Home Reference (NIH)DNAH11
Genomic and cartography
GoldenPath hg38 (UCSC)DNAH11  -     chr7:21543215-21901568 +  7p15.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAH11  -     7p15.3   [Description]    (hg19-Feb_2009)
EnsemblDNAH11 - 7p15.3 [CytoView hg19]  DNAH11 - 7p15.3 [CytoView hg38]
Mapping of homologs : NCBIDNAH11 [Mapview hg19]  DNAH11 [Mapview hg38]
OMIM603339   611884   
Gene and transcription
Genbank (Entrez)AI743846 AJ132087 AJ320497 AK054657 AK095018
RefSeq transcript (Entrez)NM_001277115
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAH11
Cluster EST : UnigeneHs.744069 [ NCBI ]
CGAP (NCI)Hs.744069
Alternative Splicing GalleryENSG00000105877
Gene ExpressionDNAH11 [ NCBI-GEO ]   DNAH11 [ EBI - ARRAY_EXPRESS ]   DNAH11 [ SEEK ]   DNAH11 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAH11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8701
GTEX Portal (Tissue expression)DNAH11
Human Protein AtlasENSG00000105877-DNAH11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DT5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DT5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DT5
Splice isoforms : SwissVarQ96DT5
PhosPhoSitePlusQ96DT5
Domains : Interpro (EBI)AAA+_ATPase    ATPase_dyneun-rel_AAA    DHC_fam    DNAH11    Dynein_HC_stalk    Dynein_heavy_chain_D4_dom    Dynein_heavy_dom    Dynein_heavy_dom-1    Dynein_heavy_dom-2    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA_5 (PF07728)    AAA_8 (PF12780)    DHC_N1 (PF08385)    DHC_N2 (PF08393)    Dynein_heavy (PF03028)    MT (PF12777)   
Domain families : Pfam (NCBI)pfam07728    pfam12780    pfam08385    pfam08393    pfam03028    pfam12777   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)DNAH11
DMDM Disease mutations8701
Blocks (Seattle)DNAH11
SuperfamilyQ96DT5
Human Protein Atlas [tissue]ENSG00000105877-DNAH11 [tissue]
Peptide AtlasQ96DT5
HPRD09134
IPIIPI00335711   IPI00984183   
Protein Interaction databases
DIP (DOE-UCLA)Q96DT5
IntAct (EBI)Q96DT5
FunCoupENSG00000105877
BioGRIDDNAH11
STRING (EMBL)DNAH11
ZODIACDNAH11
Ontologies - Pathways
QuickGOQ96DT5
Ontology : AmiGOcilium movement  regulation of cilium beat frequency  microtubule motor activity  ATP binding  cytoplasm  microtubule  cilium  determination of left/right symmetry  ATPase activity  dynein complex  flagellated sperm motility  
Ontology : EGO-EBIcilium movement  regulation of cilium beat frequency  microtubule motor activity  ATP binding  cytoplasm  microtubule  cilium  determination of left/right symmetry  ATPase activity  dynein complex  flagellated sperm motility  
NDEx NetworkDNAH11
Atlas of Cancer Signalling NetworkDNAH11
Wikipedia pathwaysDNAH11
Orthology - Evolution
OrthoDB8701
GeneTree (enSembl)ENSG00000105877
Phylogenetic Trees/Animal Genes : TreeFamDNAH11
HOVERGENQ96DT5
HOGENOMQ96DT5
Homologs : HomoloGeneDNAH11
Homology/Alignments : Family Browser (UCSC)DNAH11
Gene fusions - Rearrangements
Tumor Fusion PortalDNAH11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAH11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAH11
dbVarDNAH11
ClinVarDNAH11
1000_GenomesDNAH11 
Exome Variant ServerDNAH11
ExAC (Exome Aggregation Consortium)ENSG00000105877
GNOMAD BrowserENSG00000105877
Genetic variants : HAPMAP8701
Genomic Variants (DGV)DNAH11 [DGVbeta]
DECIPHERDNAH11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAH11 
Mutations
ICGC Data PortalDNAH11 
TCGA Data PortalDNAH11 
Broad Tumor PortalDNAH11
OASIS PortalDNAH11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAH11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNAH11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Primary Ciliary Dyskinesia variant database
BioMutasearch DNAH11
DgiDB (Drug Gene Interaction Database)DNAH11
DoCM (Curated mutations)DNAH11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAH11 (select a term)
intoGenDNAH11
Cancer3DDNAH11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603339    611884   
Orphanet665   
DisGeNETDNAH11
MedgenDNAH11
Genetic Testing Registry DNAH11
NextProtQ96DT5 [Medical]
TSGene8701
GENETestsDNAH11
Target ValidationDNAH11
Huge Navigator DNAH11 [HugePedia]
snp3D : Map Gene to Disease8701
BioCentury BCIQDNAH11
ClinGenDNAH11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8701
Chemical/Pharm GKB GenePA27396
Clinical trialDNAH11
Miscellaneous
canSAR (ICR)DNAH11 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAH11
EVEXDNAH11
GoPubMedDNAH11
iHOPDNAH11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:15:57 CET 2017

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