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DNAI2 (dynein axonemal intermediate chain 2)

Identity

Alias (NCBI)CILD9
DIC2
HGNC (Hugo) DNAI2
HGNC Alias symbCILD9
DIC2
HGNC Alias namedynein intermediate chain 2
HGNC Previous namedynein, axonemal, intermediate polypeptide 2
LocusID (NCBI) 64446
Atlas_Id 62558
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 74274210 and ends at 74314884 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM104 (17q25.1) / DNAI2 (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  TMEM104/DNAI2 (17q25)


External links

Nomenclature
HGNC (Hugo)DNAI2   18744
Cards
Entrez_Gene (NCBI)DNAI2    dynein axonemal intermediate chain 2
AliasesCILD9; DIC2
GeneCards (Weizmann)DNAI2
Ensembl hg19 (Hinxton)ENSG00000171595 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171595 [Gene_View]  ENSG00000171595 [Sequence]  chr17:74274210-74314884 [Contig_View]  DNAI2 [Vega]
ICGC DataPortalENSG00000171595
TCGA cBioPortalDNAI2
AceView (NCBI)DNAI2
Genatlas (Paris)DNAI2
SOURCE (Princeton)DNAI2
Genetics Home Reference (NIH)DNAI2
Genomic and cartography
GoldenPath hg38 (UCSC)DNAI2  -     chr17:74274210-74314884 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAI2  -     17q25.1   [Description]    (hg19-Feb_2009)
GoldenPathDNAI2 - 17q25.1 [CytoView hg19]  DNAI2 - 17q25.1 [CytoView hg38]
ImmunoBaseENSG00000171595
genome Data Viewer NCBIDNAI2 [Mapview hg19]  
OMIM605483   612444   
Gene and transcription
Genbank (Entrez)AF250288 AJ295276 AL137526 BC033013 BC039582
RefSeq transcript (Entrez)NM_001172810 NM_001353167 NM_023036
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAI2
Alternative Splicing GalleryENSG00000171595
Gene ExpressionDNAI2 [ NCBI-GEO ]   DNAI2 [ EBI - ARRAY_EXPRESS ]   DNAI2 [ SEEK ]   DNAI2 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAI2 [ Firebrowse - Broad ]
GenevisibleExpression of DNAI2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64446
GTEX Portal (Tissue expression)DNAI2
Human Protein AtlasENSG00000171595-DNAI2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZS0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZS0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZS0
Splice isoforms : SwissVarQ9GZS0
PhosPhoSitePlusQ9GZS0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_dom    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)DNAI2
Blocks (Seattle)DNAI2
SuperfamilyQ9GZS0
Human Protein Atlas [tissue]ENSG00000171595-DNAI2 [tissue]
Peptide AtlasQ9GZS0
HPRD12019
IPIIPI00304288   IPI00789929   IPI00642760   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZS0
IntAct (EBI)Q9GZS0
BioGRIDDNAI2
STRING (EMBL)DNAI2
ZODIACDNAI2
Ontologies - Pathways
QuickGOQ9GZS0
Ontology : AmiGOcilium movement  cilium movement  microtubule motor activity  protein binding  axonemal dynein complex  microtubule  axoneme  axoneme  microtubule-based movement  determination of left/right symmetry  ATP-dependent microtubule motor activity, plus-end-directed  external side of plasma membrane  sperm flagellum  outer dynein arm  outer dynein arm  outer dynein arm assembly  outer dynein arm assembly  dynein light chain binding  dynein heavy chain binding  cilium assembly  
Ontology : EGO-EBIcilium movement  cilium movement  microtubule motor activity  protein binding  axonemal dynein complex  microtubule  axoneme  axoneme  microtubule-based movement  determination of left/right symmetry  ATP-dependent microtubule motor activity, plus-end-directed  external side of plasma membrane  sperm flagellum  outer dynein arm  outer dynein arm  outer dynein arm assembly  outer dynein arm assembly  dynein light chain binding  dynein heavy chain binding  cilium assembly  
NDEx NetworkDNAI2
Atlas of Cancer Signalling NetworkDNAI2
Wikipedia pathwaysDNAI2
Orthology - Evolution
OrthoDB64446
GeneTree (enSembl)ENSG00000171595
Phylogenetic Trees/Animal Genes : TreeFamDNAI2
HOGENOMQ9GZS0
Homologs : HomoloGeneDNAI2
Homology/Alignments : Family Browser (UCSC)DNAI2
Gene fusions - Rearrangements
Fusion : QuiverDNAI2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAI2 [hg38]
dbVarDNAI2
ClinVarDNAI2
MonarchDNAI2
1000_GenomesDNAI2 
Exome Variant ServerDNAI2
GNOMAD BrowserENSG00000171595
Varsome BrowserDNAI2
Genomic Variants (DGV)DNAI2 [DGVbeta]
DECIPHERDNAI2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAI2 
Mutations
ICGC Data PortalDNAI2 
TCGA Data PortalDNAI2 
Broad Tumor PortalDNAI2
OASIS PortalDNAI2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAI2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNAI2
Mutations and Diseases : HGMDDNAI2
LOVD (Leiden Open Variation Database)Primary Ciliary Dyskinesia variant database
BioMutasearch DNAI2
DgiDB (Drug Gene Interaction Database)DNAI2
DoCM (Curated mutations)DNAI2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAI2 (select a term)
intoGenDNAI2
Cancer3DDNAI2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605483    612444   
Orphanet665   
DisGeNETDNAI2
MedgenDNAI2
Genetic Testing Registry DNAI2
NextProtQ9GZS0 [Medical]
GENETestsDNAI2
Target ValidationDNAI2
Huge Navigator DNAI2 [HugePedia]
ClinGenDNAI2
Clinical trials, drugs, therapy
MyCancerGenomeDNAI2
Protein Interactions : CTD
Pharm GKB GenePA38669
Clinical trialDNAI2
Miscellaneous
canSAR (ICR)DNAI2 (select the gene name)
HarmonizomeDNAI2
DataMed IndexDNAI2
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAI2
EVEXDNAI2
GoPubMedDNAI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:52:04 CET 2020

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