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DNAI2 (dynein axonemal intermediate chain 2)

Identity

Alias_namesdynein, axonemal, intermediate polypeptide 2
Alias_symbol (synonym)CILD9
DIC2
Other alias
HGNC (Hugo) DNAI2
LocusID (NCBI) 64446
Atlas_Id 62558
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 74274247 and ends at 74314884 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM104 (17q25.1) / DNAI2 (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNAI2   18744
Cards
Entrez_Gene (NCBI)DNAI2  64446  dynein axonemal intermediate chain 2
AliasesCILD9; DIC2
GeneCards (Weizmann)DNAI2
Ensembl hg19 (Hinxton)ENSG00000171595 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171595 [Gene_View]  chr17:74274247-74314884 [Contig_View]  DNAI2 [Vega]
ICGC DataPortalENSG00000171595
TCGA cBioPortalDNAI2
AceView (NCBI)DNAI2
Genatlas (Paris)DNAI2
WikiGenes64446
SOURCE (Princeton)DNAI2
Genetics Home Reference (NIH)DNAI2
Genomic and cartography
GoldenPath hg38 (UCSC)DNAI2  -     chr17:74274247-74314884 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAI2  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblDNAI2 - 17q25.1 [CytoView hg19]  DNAI2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIDNAI2 [Mapview hg19]  DNAI2 [Mapview hg38]
OMIM605483   612444   
Gene and transcription
Genbank (Entrez)AF250288 AJ295276 AL137526 BC033013 BC039582
RefSeq transcript (Entrez)NM_001172810 NM_023036
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAI2
Cluster EST : UnigeneHs.147472 [ NCBI ]
CGAP (NCI)Hs.147472
Alternative Splicing GalleryENSG00000171595
Gene ExpressionDNAI2 [ NCBI-GEO ]   DNAI2 [ EBI - ARRAY_EXPRESS ]   DNAI2 [ SEEK ]   DNAI2 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAI2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64446
GTEX Portal (Tissue expression)DNAI2
Human Protein AtlasENSG00000171595-DNAI2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZS0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZS0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZS0
Splice isoforms : SwissVarQ9GZS0
PhosPhoSitePlusQ9GZS0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)DNAI2
DMDM Disease mutations64446
Blocks (Seattle)DNAI2
SuperfamilyQ9GZS0
Human Protein Atlas [tissue]ENSG00000171595-DNAI2 [tissue]
Peptide AtlasQ9GZS0
HPRD12019
IPIIPI00304288   IPI00789929   IPI00642760   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZS0
IntAct (EBI)Q9GZS0
FunCoupENSG00000171595
BioGRIDDNAI2
STRING (EMBL)DNAI2
ZODIACDNAI2
Ontologies - Pathways
QuickGOQ9GZS0
Ontology : AmiGOcilium movement  microtubule motor activity  protein binding  cytoplasm  axonemal dynein complex  microtubule  axoneme  axoneme  determination of left/right symmetry  external side of plasma membrane  sperm flagellum  outer dynein arm  outer dynein arm assembly  cilium assembly  
Ontology : EGO-EBIcilium movement  microtubule motor activity  protein binding  cytoplasm  axonemal dynein complex  microtubule  axoneme  axoneme  determination of left/right symmetry  external side of plasma membrane  sperm flagellum  outer dynein arm  outer dynein arm assembly  cilium assembly  
Pathways : KEGGHuntington's disease   
NDEx NetworkDNAI2
Atlas of Cancer Signalling NetworkDNAI2
Wikipedia pathwaysDNAI2
Orthology - Evolution
OrthoDB64446
GeneTree (enSembl)ENSG00000171595
Phylogenetic Trees/Animal Genes : TreeFamDNAI2
HOVERGENQ9GZS0
HOGENOMQ9GZS0
Homologs : HomoloGeneDNAI2
Homology/Alignments : Family Browser (UCSC)DNAI2
Gene fusions - Rearrangements
Tumor Fusion PortalDNAI2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAI2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAI2
dbVarDNAI2
ClinVarDNAI2
1000_GenomesDNAI2 
Exome Variant ServerDNAI2
ExAC (Exome Aggregation Consortium)ENSG00000171595
GNOMAD BrowserENSG00000171595
Genetic variants : HAPMAP64446
Genomic Variants (DGV)DNAI2 [DGVbeta]
DECIPHERDNAI2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAI2 
Mutations
ICGC Data PortalDNAI2 
TCGA Data PortalDNAI2 
Broad Tumor PortalDNAI2
OASIS PortalDNAI2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAI2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNAI2
LOVD (Leiden Open Variation Database)Primary Ciliary Dyskinesia variant database
BioMutasearch DNAI2
DgiDB (Drug Gene Interaction Database)DNAI2
DoCM (Curated mutations)DNAI2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAI2 (select a term)
intoGenDNAI2
Cancer3DDNAI2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605483    612444   
Orphanet665   
DisGeNETDNAI2
MedgenDNAI2
Genetic Testing Registry DNAI2
NextProtQ9GZS0 [Medical]
TSGene64446
GENETestsDNAI2
Target ValidationDNAI2
Huge Navigator DNAI2 [HugePedia]
snp3D : Map Gene to Disease64446
BioCentury BCIQDNAI2
ClinGenDNAI2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64446
Chemical/Pharm GKB GenePA38669
Clinical trialDNAI2
Miscellaneous
canSAR (ICR)DNAI2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAI2
EVEXDNAI2
GoPubMedDNAI2
iHOPDNAI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:35:18 CET 2017

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