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DNAJB1 (DnaJ (Hsp40) homolog, subfamily B, member 1)

Identity

Other namesHSPF1
Hdj1
Hsp40
RSPH16B
Sis1
HGNC (Hugo) DNAJB1
LocusID (NCBI) 3337
Location 19p13.12
Location_base_pair Starts at 14625582 and ends at 14629201 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DNAJB1   5270
Cards
Entrez_Gene (NCBI)DNAJB1  3337  DnaJ (Hsp40) homolog, subfamily B, member 1
GeneCards (Weizmann)DNAJB1
Ensembl hg19 (Hinxton)ENSG00000132002 [Gene_View]  chr19:14625582-14629201 [Contig_View]  DNAJB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132002 [Gene_View]  chr19:14625582-14629201 [Contig_View]  DNAJB1 [Vega]
ICGC DataPortalENSG00000132002
cBioPortalDNAJB1
AceView (NCBI)DNAJB1
Genatlas (Paris)DNAJB1
WikiGenes3337
SOURCE (Princeton)DNAJB1
Genomic and cartography
GoldenPath hg19 (UCSC)DNAJB1  -     chr19:14625582-14629201 -  19p13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DNAJB1  -     19p13.12   [Description]    (hg38-Dec_2013)
EnsemblDNAJB1 - 19p13.12 [CytoView hg19]  DNAJB1 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBIDNAJB1 [Mapview hg19]  DNAJB1 [Mapview hg38]
OMIM604572   
Gene and transcription
Genbank (Entrez)AK092989 AK301817 AK312624 BC002352 BC013157
RefSeq transcript (Entrez)NM_001300914 NM_006145
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NT_011295 NW_001838483 NW_004929414
Consensus coding sequences : CCDS (NCBI)DNAJB1
Cluster EST : UnigeneHs.515210 [ NCBI ]
CGAP (NCI)Hs.515210
Alternative Splicing : Fast-db (Paris)GSHG0015570
Alternative Splicing GalleryENSG00000132002
Gene ExpressionDNAJB1 [ NCBI-GEO ]     DNAJB1 [ SEEK ]   DNAJB1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25685 (Uniprot)
NextProtP25685  [Medical]
With graphics : InterProP25685
Splice isoforms : SwissVarP25685 (Swissvar)
Domaine pattern : Prosite (Expaxy)DNAJ_1 (PS00636)    DNAJ_2 (PS50076)   
Domains : Interpro (EBI)DnaJ_C    DnaJ_domain    DnaJ_domain_CS    HSP40/DnaJ_pept-bd   
Related proteins : CluSTrP25685
Domain families : Pfam (Sanger)CTDII (PF01556)    DnaJ (PF00226)   
Domain families : Pfam (NCBI)pfam01556    pfam00226   
Domain families : Smart (EMBL)DnaJ (SM00271)  
DMDM Disease mutations3337
Blocks (Seattle)P25685
PDB (SRS)1HDJ    2QLD    3AGX    3AGY    3AGZ   
PDB (PDBSum)1HDJ    2QLD    3AGX    3AGY    3AGZ   
PDB (IMB)1HDJ    2QLD    3AGX    3AGY    3AGZ   
PDB (RSDB)1HDJ    2QLD    3AGX    3AGY    3AGZ   
Human Protein AtlasENSG00000132002
Peptide AtlasP25685
HPRD05198
IPIIPI00015947   IPI01010489   IPI00984730   
Protein Interaction databases
DIP (DOE-UCLA)P25685
IntAct (EBI)P25685
FunCoupENSG00000132002
BioGRIDDNAJB1
IntegromeDBDNAJB1
STRING (EMBL)DNAJB1
Ontologies - Pathways
QuickGOP25685
Ontology : AmiGOATPase activator activity  protein binding  nucleus  nucleolus  cytosol  response to unfolded protein  Hsp70 protein binding  positive regulation of ATPase activity  unfolded protein binding  chaperone mediated protein folding requiring cofactor  chaperone binding  ATPase binding  extracellular vesicular exosome  chaperone cofactor-dependent protein refolding  negative regulation of inclusion body assembly  
Ontology : EGO-EBIATPase activator activity  protein binding  nucleus  nucleolus  cytosol  response to unfolded protein  Hsp70 protein binding  positive regulation of ATPase activity  unfolded protein binding  chaperone mediated protein folding requiring cofactor  chaperone binding  ATPase binding  extracellular vesicular exosome  chaperone cofactor-dependent protein refolding  negative regulation of inclusion body assembly  
Pathways : BIOCARTAPrion Pathway [Genes]    Hypoxia and p53 in the Cardiovascular system [Genes]   
Pathways : KEGGProtein processing in endoplasmic reticulum    Influenza A   
Protein Interaction DatabaseDNAJB1
DoCM (Curated mutations)DNAJB1
Wikipedia pathwaysDNAJB1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerDNAJB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAJB1
dbVarDNAJB1
ClinVarDNAJB1
1000_GenomesDNAJB1 
Exome Variant ServerDNAJB1
SNP (GeneSNP Utah)DNAJB1
SNP : HGBaseDNAJB1
Genetic variants : HAPMAPDNAJB1
Genomic VariantsDNAJB1  DNAJB1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000132002 
Somatic Mutations in Cancer : COSMICDNAJB1 
CONAN: Copy Number AnalysisDNAJB1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:14625582-14629201
Mutations and Diseases : HGMDDNAJB1
OMIM604572   
MedgenDNAJB1
NextProtP25685 [Medical]
GENETestsDNAJB1
Disease Genetic AssociationDNAJB1
Huge Navigator DNAJB1 [HugePedia]  DNAJB1 [HugeCancerGEM]
snp3D : Map Gene to Disease3337
DGIdb (Drug Gene Interaction db)DNAJB1
General knowledge
Homologs : HomoloGeneDNAJB1
Homology/Alignments : Family Browser (UCSC)DNAJB1
Phylogenetic Trees/Animal Genes : TreeFamDNAJB1
Chemical/Protein Interactions : CTD3337
Chemical/Pharm GKB GenePA27412
Clinical trialDNAJB1
Cancer Resource (Charite)ENSG00000132002
Other databases
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
CoreMineDNAJB1
GoPubMedDNAJB1
iHOPDNAJB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 20 21:14:05 CET 2014

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