Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DNAJC1 (DnaJ heat shock protein family (Hsp40) member C1)

Identity

Alias (NCBI)DNAJL1
ERdj1
HTJ1
MTJ1
HGNC (Hugo) DNAJC1
HGNC Alias symbDNAJL1
ERdj1
MTJ1
HGNC Previous nameDnaJ (Hsp40) homolog, subfamily C, member 1
LocusID (NCBI) 64215
Atlas_Id 47352
Location 10p12.31  [Link to chromosome band 10p12]
Location_base_pair Starts at 21756548 and ends at 22003730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APBB1IP (10p12.1) / DNAJC1 (10p12.31)DNAJC1 (10p12.31) / DCLRE1C (10p13)DNAJC1 (10p12.31) / DNAJC1 (10p12.31)
DNAJC1 (10p12.31) / GTDC1 (2q22.3)DNAJC1 (10p12.31) / MYB (6q23.3)DNAJC1 (10p12.31) / PLEKHF2 (8q22.1)
DNAJC1 (10p12.31) / SFTPD (10q22.3)NEBL (10p12.31) / DNAJC1 (10p12.31)TAF3 (10p14) / DNAJC1 (10p12.31)
ZNF462 (9q31.2) / DNAJC1 (10p12.31)APBB1IP 10p12.1 / DNAJC1 10p12.31DNAJC1 10p12.31 / DCLRE1C 10p13
DNAJC1 10p12.31 / PLEKHF2 8q22.1NEBL 10p12.31 / DNAJC1 10p12.31TAF3 10p14 / DNAJC1 10p12.31
ZNF462 9q31.2 / DNAJC1 10p12.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DNAJC1   20090
Cards
Entrez_Gene (NCBI)DNAJC1    DnaJ heat shock protein family (Hsp40) member C1
AliasesDNAJL1; ERdj1; HTJ1; MTJ1
GeneCards (Weizmann)DNAJC1
Ensembl hg19 (Hinxton)ENSG00000136770 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136770 [Gene_View]  ENSG00000136770 [Sequence]  chr10:21756548-22003730 [Contig_View]  DNAJC1 [Vega]
ICGC DataPortalENSG00000136770
TCGA cBioPortalDNAJC1
AceView (NCBI)DNAJC1
Genatlas (Paris)DNAJC1
SOURCE (Princeton)DNAJC1
Genetics Home Reference (NIH)DNAJC1
Genomic and cartography
GoldenPath hg38 (UCSC)DNAJC1  -     chr10:21756548-22003730 -  10p12.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAJC1  -     10p12.31   [Description]    (hg19-Feb_2009)
GoldenPathDNAJC1 - 10p12.31 [CytoView hg19]  DNAJC1 - 10p12.31 [CytoView hg38]
ImmunoBaseENSG00000136770
Genome Data Viewer NCBIDNAJC1 [Mapview hg19]  
OMIM611207   
Gene and transcription
Genbank (Entrez)AF427142 AK026062 AK027263 AK308369 AY225122
RefSeq transcript (Entrez)NM_022365
Consensus coding sequences : CCDS (NCBI)DNAJC1
Gene ExpressionDNAJC1 [ NCBI-GEO ]   DNAJC1 [ EBI - ARRAY_EXPRESS ]   DNAJC1 [ SEEK ]   DNAJC1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAJC1 [ Firebrowse - Broad ]
GenevisibleExpression of DNAJC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64215
GTEX Portal (Tissue expression)DNAJC1
Human Protein AtlasENSG00000136770-DNAJC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KC8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KC8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KC8
PhosPhoSitePlusQ96KC8
Domaine pattern : Prosite (Expaxy)DNAJ_1 (PS00636)    DNAJ_2 (PS50076)    SANT (PS51293)   
Domains : Interpro (EBI)DnaJ_domain    DnaJ_domain_CS    Homeobox-like_sf    J_dom_sf    SANT/Myb    SANT_dom   
Domain families : Pfam (Sanger)DnaJ (PF00226)    Myb_DNA-binding (PF00249)   
Domain families : Pfam (NCBI)pfam00226    pfam00249   
Domain families : Smart (EMBL)DnaJ (SM00271)  SANT (SM00717)  
Conserved Domain (NCBI)DNAJC1
PDB (RSDB)2CQQ    2CQR   
PDB Europe2CQQ    2CQR   
PDB (PDBSum)2CQQ    2CQR   
PDB (IMB)2CQQ    2CQR   
Structural Biology KnowledgeBase2CQQ    2CQR   
SCOP (Structural Classification of Proteins)2CQQ    2CQR   
CATH (Classification of proteins structures)2CQQ    2CQR   
SuperfamilyQ96KC8
AlphaFold pdb e-kbQ96KC8   
Human Protein Atlas [tissue]ENSG00000136770-DNAJC1 [tissue]
HPRD09922
Protein Interaction databases
DIP (DOE-UCLA)Q96KC8
IntAct (EBI)Q96KC8
BioGRIDDNAJC1
STRING (EMBL)DNAJC1
ZODIACDNAJC1
Ontologies - Pathways
QuickGOQ96KC8
Ontology : AmiGOATPase activator activity  DNA binding  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  regulation of translation  protein folding  membrane  integral component of membrane  nuclear membrane  negative regulation of proteolysis  regulation of protein secretion  regulation of catalytic activity  chaperone binding  
Ontology : EGO-EBIATPase activator activity  DNA binding  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  regulation of translation  protein folding  membrane  integral component of membrane  nuclear membrane  negative regulation of proteolysis  regulation of protein secretion  regulation of catalytic activity  chaperone binding  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkDNAJC1
Atlas of Cancer Signalling NetworkDNAJC1
Wikipedia pathwaysDNAJC1
Orthology - Evolution
OrthoDB64215
GeneTree (enSembl)ENSG00000136770
Phylogenetic Trees/Animal Genes : TreeFamDNAJC1
Homologs : HomoloGeneDNAJC1
Homology/Alignments : Family Browser (UCSC)DNAJC1
Gene fusions - Rearrangements
Fusion : MitelmanAPBB1IP/DNAJC1 [10p12.1/10p12.31]  
Fusion : MitelmanDNAJC1/DCLRE1C [10p12.31/10p13]  
Fusion : MitelmanDNAJC1/PLEKHF2 [10p12.31/8q22.1]  
Fusion : MitelmanDNAJC1/SFTPD [10p12.31/10q22.3]  
Fusion : MitelmanNEBL/DNAJC1 [10p12.31/10p12.31]  
Fusion : MitelmanTAF3/DNAJC1 [10p14/10p12.31]  
Fusion : MitelmanZNF462/DNAJC1 [9q31.2/10p12.31]  
Fusion : QuiverDNAJC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAJC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAJC1
dbVarDNAJC1
ClinVarDNAJC1
MonarchDNAJC1
1000_GenomesDNAJC1 
Exome Variant ServerDNAJC1
GNOMAD BrowserENSG00000136770
Varsome BrowserDNAJC1
ACMGDNAJC1 variants
VarityQ96KC8
Genomic Variants (DGV)DNAJC1 [DGVbeta]
DECIPHERDNAJC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAJC1 
Mutations
ICGC Data PortalDNAJC1 
TCGA Data PortalDNAJC1 
Broad Tumor PortalDNAJC1
OASIS PortalDNAJC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAJC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNAJC1
Mutations and Diseases : HGMDDNAJC1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDNAJC1
DgiDB (Drug Gene Interaction Database)DNAJC1
DoCM (Curated mutations)DNAJC1
CIViC (Clinical Interpretations of Variants in Cancer)DNAJC1
Cancer3DDNAJC1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611207   
Orphanet
DisGeNETDNAJC1
MedgenDNAJC1
Genetic Testing Registry DNAJC1
NextProtQ96KC8 [Medical]
GENETestsDNAJC1
Target ValidationDNAJC1
Huge Navigator DNAJC1 [HugePedia]
ClinGenDNAJC1
Clinical trials, drugs, therapy
MyCancerGenomeDNAJC1
Protein Interactions : CTDDNAJC1
Pharm GKB GenePA128394706
PharosQ96KC8
Clinical trialDNAJC1
Miscellaneous
canSAR (ICR)DNAJC1
HarmonizomeDNAJC1
DataMed IndexDNAJC1
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDNAJC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:07:01 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.