Identity
HGNC
LOCATION
2q32.1
LOCUSID
ALIAS
ERdj5,JPDI,MTHr,PDIA19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54431
MIM: 607987
HGNC: 24637
Ensembl: ENSG00000077232
Variants:
dbSNP: 54431
ClinVar: 54431
TCGA: ENSG00000077232
COSMIC: DNAJC10
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Protein processing in endoplasmic reticulum | KEGG | ko04141 |
| Protein processing in endoplasmic reticulum | KEGG | hsa04141 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37496439 | 2024 | DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response. | 1 |
| 37496439 | 2024 | DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response. | 1 |
| 37739037 | 2023 | Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP. | 0 |
| 37739037 | 2023 | Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP. | 0 |
| 34988580 | 2022 | DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients. | 5 |
| 34988580 | 2022 | DNAJC10 correlates with tumor immune characteristics and predicts the prognosis of glioma patients. | 5 |
| 31902119 | 2020 | Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer. | 7 |
| 32196553 | 2020 | AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity. | 8 |
| 31902119 | 2020 | Downregulation of DNAJC10 (ERDJ5) is associated with poor survival in breast cancer. | 7 |
| 32196553 | 2020 | AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity. | 8 |
| 30967862 | 2019 | Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients. | 8 |
| 30967862 | 2019 | Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients. | 8 |
| 28479060 | 2017 | The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation. | 15 |
| 28479060 | 2017 | The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation. | 15 |
| 25055872 | 2014 | The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control. | 17 |
Citation
Dessen P
DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46418/dnajc10
