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DNAJC10 (DnaJ (Hsp40) homolog, subfamily C, member 10)

Identity

Other namesERdj5
JPDI
MTHr
PDIA19
HGNC (Hugo) DNAJC10
LocusID (NCBI) 54431
Atlas_Id 46418
Location 2q32.1
Location_base_pair Starts at 183580768 and ends at 183644750 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DNAJC10   24637
Cards
Entrez_Gene (NCBI)DNAJC10  54431  DnaJ (Hsp40) homolog, subfamily C, member 10
GeneCards (Weizmann)DNAJC10
Ensembl hg19 (Hinxton)ENSG00000077232 [Gene_View]  chr2:183580768-183644750 [Contig_View]  DNAJC10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000077232 [Gene_View]  chr2:183580768-183644750 [Contig_View]  DNAJC10 [Vega]
ICGC DataPortalENSG00000077232
TCGA cBioPortalDNAJC10
AceView (NCBI)DNAJC10
Genatlas (Paris)DNAJC10
WikiGenes54431
SOURCE (Princeton)DNAJC10
Genomic and cartography
GoldenPath hg19 (UCSC)DNAJC10  -     chr2:183580768-183644750 +  2q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DNAJC10  -     2q32.1   [Description]    (hg38-Dec_2013)
EnsemblDNAJC10 - 2q32.1 [CytoView hg19]  DNAJC10 - 2q32.1 [CytoView hg38]
Mapping of homologs : NCBIDNAJC10 [Mapview hg19]  DNAJC10 [Mapview hg38]
OMIM607987   
Gene and transcription
Genbank (Entrez)AA651917 AF038503 AF314529 AF490904 AK027450
RefSeq transcript (Entrez)NM_001271581 NM_018981
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)DNAJC10
Cluster EST : UnigeneHs.744512 [ NCBI ]
CGAP (NCI)Hs.744512
Alternative Splicing : Fast-db (Paris)GSHG0017044
Alternative Splicing GalleryENSG00000077232
Gene ExpressionDNAJC10 [ NCBI-GEO ]     DNAJC10 [ SEEK ]   DNAJC10 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXB1 (Uniprot)
NextProtQ8IXB1  [Medical]
With graphics : InterProQ8IXB1
Splice isoforms : SwissVarQ8IXB1 (Swissvar)
Catalytic activity : Enzyme1.8.4.- [ Enzyme-Expasy ]   1.8.4.-1.8.4.- [ IntEnz-EBI ]   1.8.4.- [ BRENDA ]   1.8.4.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)DNAJ_2 (PS50076)    ER_TARGET (PS00014)    THIOREDOXIN_1 (PS00194)    THIOREDOXIN_2 (PS51352)   
Domains : Interpro (EBI)DnaJ_domain    DnaJ_homolog_subfam-C    Thioredoxin-like_fold    Thioredoxin_CS    Thioredoxin_domain   
Related proteins : CluSTrQ8IXB1
Domain families : Pfam (Sanger)DnaJ (PF00226)    Thioredoxin (PF00085)   
Domain families : Pfam (NCBI)pfam00226    pfam00085   
Domain families : Smart (EMBL)DnaJ (SM00271)  
DMDM Disease mutations54431
Blocks (Seattle)Q8IXB1
Human Protein AtlasENSG00000077232
Peptide AtlasQ8IXB1
HPRD09722
IPIIPI00293260   IPI00844115   IPI01026420   IPI00873764   IPI01012003   IPI01016006   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXB1
IntAct (EBI)Q8IXB1
FunCoupENSG00000077232
BioGRIDDNAJC10
IntegromeDBDNAJC10
STRING (EMBL)DNAJC10
Ontologies - Pathways
QuickGOQ8IXB1
Ontology : AmiGOATPase activator activity  negative regulation of protein phosphorylation  protein binding  endoplasmic reticulum  endoplasmic reticulum lumen  protein disulfide oxidoreductase activity  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  membrane  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  ER-associated ubiquitin-dependent protein catabolic process  Hsp70 protein binding  positive regulation of ATPase activity  endoplasmic reticulum chaperone complex  protein folding in endoplasmic reticulum  response to endoplasmic reticulum stress  cell redox homeostasis  chaperone binding  ATPase binding  misfolded protein binding  oxidation-reduction process  intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  
Ontology : EGO-EBIATPase activator activity  negative regulation of protein phosphorylation  protein binding  endoplasmic reticulum  endoplasmic reticulum lumen  protein disulfide oxidoreductase activity  protein disulfide oxidoreductase activity  disulfide oxidoreductase activity  membrane  oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor  ER-associated ubiquitin-dependent protein catabolic process  Hsp70 protein binding  positive regulation of ATPase activity  endoplasmic reticulum chaperone complex  protein folding in endoplasmic reticulum  response to endoplasmic reticulum stress  cell redox homeostasis  chaperone binding  ATPase binding  misfolded protein binding  oxidation-reduction process  intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  
Pathways : KEGGProtein processing in endoplasmic reticulum   
Protein Interaction DatabaseDNAJC10
DoCM (Curated mutations)DNAJC10
Wikipedia pathwaysDNAJC10
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerDNAJC10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAJC10
dbVarDNAJC10
ClinVarDNAJC10
1000_GenomesDNAJC10 
Exome Variant ServerDNAJC10
SNP (GeneSNP Utah)DNAJC10
SNP : HGBaseDNAJC10
Genetic variants : HAPMAPDNAJC10
Genomic Variants (DGV)DNAJC10 [DGVbeta]
Mutations
ICGC Data PortalDNAJC10 
TCGA Data PortalDNAJC10 
Tumor PortalDNAJC10
Somatic Mutations in Cancer : COSMICDNAJC10 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:183580768-183644750
CONAN: Copy Number AnalysisDNAJC10 
Mutations and Diseases : HGMDDNAJC10
OMIM607987   
MedgenDNAJC10
NextProtQ8IXB1 [Medical]
GENETestsDNAJC10
Disease Genetic AssociationDNAJC10
Huge Navigator DNAJC10 [HugePedia]  DNAJC10 [HugeCancerGEM]
snp3D : Map Gene to Disease54431
DGIdb (Drug Gene Interaction db)DNAJC10
General knowledge
Homologs : HomoloGeneDNAJC10
Homology/Alignments : Family Browser (UCSC)DNAJC10
Phylogenetic Trees/Animal Genes : TreeFamDNAJC10
Chemical/Protein Interactions : CTD54431
Chemical/Pharm GKB GenePA134917195
Clinical trialDNAJC10
Cancer Resource (Charite)ENSG00000077232
Other databases
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
CoreMineDNAJC10
GoPubMedDNAJC10
iHOPDNAJC10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 14:20:14 CEST 2015

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