DNAJC14 (DnaJ heat shock protein family (Hsp40) member C14)

2007-04-01  

Identity

HGNC
DNAJC14
LOCATION
12q13.2
LOCUSID
85406
ALIAS
DNAJ,DRIP78,HDJ3,LIP6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 85406
MIM: 606092
HGNC: 24581
Ensembl: ENSG00000135392

Variants:

dbSNP: 85406
ClinVar: 85406
TCGA: ENSG00000135392
COSMIC: DNAJC14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135392ENST00000317269Q6Y2X3
ENSG00000135392ENST00000317269A0A024RB64
ENSG00000135392ENST00000317287Q6Y2X3
ENSG00000135392ENST00000317287A0A024RB64
ENSG00000135392ENST00000357606Q6Y2X3
ENSG00000135392ENST00000357606A0A024RB64
ENSG00000135392ENST00000546957F8VYY5
ENSG00000135392ENST00000547445F8VNT6
ENSG00000135392ENST00000646577A0A2R8Y716

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
212491762011Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator.34
229158032012Flavivirus replication complex assembly revealed by DNAJC14 functional mapping.16
271096332016The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion.14
267390572016Chaperone-Assisted Protein Folding Is Critical for Yellow Fever Virus NS3/4A Cleavage and Replication.10
228157582012Dopamine receptor-interacting protein 78 acts as a molecular chaperone for CCR5 chemokine receptor signaling complex organization.9

Citation

Dessen P

DNAJC14 (DnaJ heat shock protein family (Hsp40) member C14)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46692/dnajc14