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DNAJC4 (DnaJ heat shock protein family (Hsp40) member C4)

Identity

Alias_namesHSPF2
DnaJ (Hsp40) homolog
Alias_symbol (synonym)MCG18
Other aliasDANJC4
HGNC (Hugo) DNAJC4
LocusID (NCBI) 3338
Atlas_Id 46928
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 64230281 and ends at 64234281 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAJC4 (11q13.1) / NUDT22 (11q13.1)DNAJC4 (11q13.1) / PPP2R3B (Xp22.33)DNAJC4 11q13.1 / NUDT22 11q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q13;q13) DNAJC4/NUDT22

External links

Nomenclature
HGNC (Hugo)DNAJC4   5271
Cards
Entrez_Gene (NCBI)DNAJC4  3338  DnaJ heat shock protein family (Hsp40) member C4
AliasesDANJC4; HSPF2; MCG18
GeneCards (Weizmann)DNAJC4
Ensembl hg19 (Hinxton)ENSG00000110011 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110011 [Gene_View]  chr11:64230281-64234281 [Contig_View]  DNAJC4 [Vega]
ICGC DataPortalENSG00000110011
TCGA cBioPortalDNAJC4
AceView (NCBI)DNAJC4
Genatlas (Paris)DNAJC4
WikiGenes3338
SOURCE (Princeton)DNAJC4
Genetics Home Reference (NIH)DNAJC4
Genomic and cartography
GoldenPath hg38 (UCSC)DNAJC4  -     chr11:64230281-64234281 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAJC4  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblDNAJC4 - 11q13.1 [CytoView hg19]  DNAJC4 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBIDNAJC4 [Mapview hg19]  DNAJC4 [Mapview hg38]
OMIM604189   
Gene and transcription
Genbank (Entrez)AA504260 AF012106 AF036874 BC010145 BC032137
RefSeq transcript (Entrez)NM_001307980 NM_001307981 NM_005528
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAJC4
Cluster EST : UnigeneHs.172847 [ NCBI ]
CGAP (NCI)Hs.172847
Alternative Splicing GalleryENSG00000110011
Gene ExpressionDNAJC4 [ NCBI-GEO ]   DNAJC4 [ EBI - ARRAY_EXPRESS ]   DNAJC4 [ SEEK ]   DNAJC4 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAJC4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3338
GTEX Portal (Tissue expression)DNAJC4
Human Protein AtlasENSG00000110011-DNAJC4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NNZ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NNZ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NNZ3
Splice isoforms : SwissVarQ9NNZ3
PhosPhoSitePlusQ9NNZ3
Domaine pattern : Prosite (Expaxy)DNAJ_2 (PS50076)   
Domains : Interpro (EBI)DnaJ_domain   
Domain families : Pfam (Sanger)DnaJ (PF00226)   
Domain families : Pfam (NCBI)pfam00226   
Domain families : Smart (EMBL)DnaJ (SM00271)  
Conserved Domain (NCBI)DNAJC4
DMDM Disease mutations3338
Blocks (Seattle)DNAJC4
SuperfamilyQ9NNZ3
Human Protein Atlas [tissue]ENSG00000110011-DNAJC4 [tissue]
Peptide AtlasQ9NNZ3
IPIIPI00328890   IPI00867696   IPI00386683   IPI01013241   IPI01014039   
Protein Interaction databases
DIP (DOE-UCLA)Q9NNZ3
IntAct (EBI)Q9NNZ3
FunCoupENSG00000110011
BioGRIDDNAJC4
STRING (EMBL)DNAJC4
ZODIACDNAJC4
Ontologies - Pathways
QuickGOQ9NNZ3
Ontology : AmiGOprotein binding  protein folding  response to unfolded protein  membrane  integral component of membrane  unfolded protein binding  
Ontology : EGO-EBIprotein binding  protein folding  response to unfolded protein  membrane  integral component of membrane  unfolded protein binding  
NDEx NetworkDNAJC4
Atlas of Cancer Signalling NetworkDNAJC4
Wikipedia pathwaysDNAJC4
Orthology - Evolution
OrthoDB3338
GeneTree (enSembl)ENSG00000110011
Phylogenetic Trees/Animal Genes : TreeFamDNAJC4
HOVERGENQ9NNZ3
HOGENOMQ9NNZ3
Homologs : HomoloGeneDNAJC4
Homology/Alignments : Family Browser (UCSC)DNAJC4
Gene fusions - Rearrangements
Fusion : MitelmanDNAJC4/NUDT22 [11q13.1/11q13.1]  
Fusion: TCGA_MDACCDNAJC4 11q13.1 NUDT22 11q13.1 LUAD
Fusion PortalDNAJC4 11q13.1 NUDT22 11q13.1 LUAD
Fusion : QuiverDNAJC4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAJC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAJC4
dbVarDNAJC4
ClinVarDNAJC4
1000_GenomesDNAJC4 
Exome Variant ServerDNAJC4
ExAC (Exome Aggregation Consortium)ENSG00000110011
GNOMAD BrowserENSG00000110011
Genetic variants : HAPMAP3338
Genomic Variants (DGV)DNAJC4 [DGVbeta]
DECIPHERDNAJC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAJC4 
Mutations
ICGC Data PortalDNAJC4 
TCGA Data PortalDNAJC4 
Broad Tumor PortalDNAJC4
OASIS PortalDNAJC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAJC4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNAJC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DNAJC4
DgiDB (Drug Gene Interaction Database)DNAJC4
DoCM (Curated mutations)DNAJC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAJC4 (select a term)
intoGenDNAJC4
Cancer3DDNAJC4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604189   
Orphanet
DisGeNETDNAJC4
MedgenDNAJC4
Genetic Testing Registry DNAJC4
NextProtQ9NNZ3 [Medical]
TSGene3338
GENETestsDNAJC4
Target ValidationDNAJC4
Huge Navigator DNAJC4 [HugePedia]
snp3D : Map Gene to Disease3338
BioCentury BCIQDNAJC4
ClinGenDNAJC4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3338
Chemical/Pharm GKB GenePA27421
Clinical trialDNAJC4
Miscellaneous
canSAR (ICR)DNAJC4 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAJC4
EVEXDNAJC4
GoPubMedDNAJC4
iHOPDNAJC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:09:59 CET 2018
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