Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6)

Identity

Alias_namesDnaJ (Hsp40) homolog
Alias_symbol (synonym)KIAA0473
PARK19
Other aliasDJC6
HGNC (Hugo) DNAJC6
LocusID (NCBI) 9829
Atlas_Id 46727
Location 1p31.3  [Link to chromosome band 1p31]
Location_base_pair Starts at 65264694 and ends at 65415869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAJC6 (1p31.3) / PDE1C (7p14.3)DNAJC6 (1p31.3) / SPAG16 (2q34)PATJ (1p31.3) / DNAJC6 (1p31.3)
DNAJC6 1p31.3 / PDE1C 7p14.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;7)(p31;p14) DNAJC6/PDE1C


External links

Nomenclature
HGNC (Hugo)DNAJC6   15469
Cards
Entrez_Gene (NCBI)DNAJC6  9829  DnaJ heat shock protein family (Hsp40) member C6
AliasesDJC6; PARK19
GeneCards (Weizmann)DNAJC6
Ensembl hg19 (Hinxton)ENSG00000116675 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116675 [Gene_View]  ENSG00000116675 [Sequence]  chr1:65264694-65415869 [Contig_View]  DNAJC6 [Vega]
ICGC DataPortalENSG00000116675
TCGA cBioPortalDNAJC6
AceView (NCBI)DNAJC6
Genatlas (Paris)DNAJC6
WikiGenes9829
SOURCE (Princeton)DNAJC6
Genetics Home Reference (NIH)DNAJC6
Genomic and cartography
GoldenPath hg38 (UCSC)DNAJC6  -     chr1:65264694-65415869 +  1p31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNAJC6  -     1p31.3   [Description]    (hg19-Feb_2009)
EnsemblDNAJC6 - 1p31.3 [CytoView hg19]  DNAJC6 - 1p31.3 [CytoView hg38]
Mapping of homologs : NCBIDNAJC6 [Mapview hg19]  DNAJC6 [Mapview hg38]
OMIM608375   615528   
Gene and transcription
Genbank (Entrez)AB007942 AK296408 BC051722 BC109279 BC109280
RefSeq transcript (Entrez)NM_001256864 NM_001256865 NM_014787
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNAJC6
Cluster EST : UnigeneHs.647643 [ NCBI ]
CGAP (NCI)Hs.647643
Alternative Splicing GalleryENSG00000116675
Gene ExpressionDNAJC6 [ NCBI-GEO ]   DNAJC6 [ EBI - ARRAY_EXPRESS ]   DNAJC6 [ SEEK ]   DNAJC6 [ MEM ]
Gene Expression Viewer (FireBrowse)DNAJC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9829
GTEX Portal (Tissue expression)DNAJC6
Human Protein AtlasENSG00000116675-DNAJC6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75061   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75061  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75061
Splice isoforms : SwissVarO75061
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.483.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
PhosPhoSitePlusO75061
Domaine pattern : Prosite (Expaxy)C2_TENSIN (PS51182)    DNAJ_2 (PS50076)    PPASE_TENSIN (PS51181)   
Domains : Interpro (EBI)C2_dom    DnaJ_domain    Prot-tyrosine_phosphatase-like    Tensin_C2-dom    Tensin_lipid_phosphatase_dom   
Domain families : Pfam (Sanger)DnaJ (PF00226)    PTEN_C2 (PF10409)   
Domain families : Pfam (NCBI)pfam00226    pfam10409   
Domain families : Smart (EMBL)DnaJ (SM00271)  PTEN_C2 (SM01326)  
Conserved Domain (NCBI)DNAJC6
DMDM Disease mutations9829
Blocks (Seattle)DNAJC6
SuperfamilyO75061
Human Protein Atlas [tissue]ENSG00000116675-DNAJC6 [tissue]
Peptide AtlasO75061
HPRD16326
IPIIPI00639806   IPI00184119   IPI00760699   
Protein Interaction databases
DIP (DOE-UCLA)O75061
IntAct (EBI)O75061
FunCoupENSG00000116675
BioGRIDDNAJC6
STRING (EMBL)DNAJC6
ZODIACDNAJC6
Ontologies - Pathways
QuickGOO75061
Ontology : AmiGOprotein tyrosine phosphatase activity  cytosol  receptor-mediated endocytosis  postsynaptic density  synaptic vesicle uncoating  SH3 domain binding  vesicle  peptidyl-tyrosine dephosphorylation  membrane organization  regulation of clathrin-dependent endocytosis  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  cytosol  receptor-mediated endocytosis  postsynaptic density  synaptic vesicle uncoating  SH3 domain binding  vesicle  peptidyl-tyrosine dephosphorylation  membrane organization  regulation of clathrin-dependent endocytosis  
NDEx NetworkDNAJC6
Atlas of Cancer Signalling NetworkDNAJC6
Wikipedia pathwaysDNAJC6
Orthology - Evolution
OrthoDB9829
GeneTree (enSembl)ENSG00000116675
Phylogenetic Trees/Animal Genes : TreeFamDNAJC6
HOVERGENO75061
HOGENOMO75061
Homologs : HomoloGeneDNAJC6
Homology/Alignments : Family Browser (UCSC)DNAJC6
Gene fusions - Rearrangements
Fusion : MitelmanDNAJC6/PDE1C [1p31.3/7p14.3]  
Fusion PortalDNAJC6 1p31.3 PDE1C 7p14.3 THCA
Fusion : QuiverDNAJC6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNAJC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNAJC6
dbVarDNAJC6
ClinVarDNAJC6
1000_GenomesDNAJC6 
Exome Variant ServerDNAJC6
ExAC (Exome Aggregation Consortium)ENSG00000116675
GNOMAD BrowserENSG00000116675
Genetic variants : HAPMAP9829
Genomic Variants (DGV)DNAJC6 [DGVbeta]
DECIPHERDNAJC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNAJC6 
Mutations
ICGC Data PortalDNAJC6 
TCGA Data PortalDNAJC6 
Broad Tumor PortalDNAJC6
OASIS PortalDNAJC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNAJC6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNAJC6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNAJC6
DgiDB (Drug Gene Interaction Database)DNAJC6
DoCM (Curated mutations)DNAJC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNAJC6 (select a term)
intoGenDNAJC6
Cancer3DDNAJC6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608375    615528   
Orphanet932    22620   
DisGeNETDNAJC6
MedgenDNAJC6
Genetic Testing Registry DNAJC6
NextProtO75061 [Medical]
TSGene9829
GENETestsDNAJC6
Target ValidationDNAJC6
Huge Navigator DNAJC6 [HugePedia]
snp3D : Map Gene to Disease9829
BioCentury BCIQDNAJC6
ClinGenDNAJC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9829
Chemical/Pharm GKB GenePA27423
Clinical trialDNAJC6
Miscellaneous
canSAR (ICR)DNAJC6 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNAJC6
EVEXDNAJC6
GoPubMedDNAJC6
iHOPDNAJC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:23:00 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.