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DNASE1L1 (deoxyribonuclease I-like 1)

Identity

Alias_namesDNL1L
deoxyribonuclease I-like 1
Alias_symbol (synonym)DNAS1L1
XIB
DNASEX
Other aliasG4.8
HGNC (Hugo) DNASE1L1
LocusID (NCBI) 1774
Atlas_Id 53843
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153629577 and ends at 153640428 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNASE1L1   2957
Cards
Entrez_Gene (NCBI)DNASE1L1  1774  deoxyribonuclease I-like 1
AliasesDNAS1L1; DNASEX; DNL1L; G4.8; 
XIB
GeneCards (Weizmann)DNASE1L1
Ensembl hg19 (Hinxton)ENSG00000013563 [Gene_View]  chrX:153629577-153640428 [Contig_View]  DNASE1L1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000013563 [Gene_View]  chrX:153629577-153640428 [Contig_View]  DNASE1L1 [Vega]
ICGC DataPortalENSG00000013563
TCGA cBioPortalDNASE1L1
AceView (NCBI)DNASE1L1
Genatlas (Paris)DNASE1L1
WikiGenes1774
SOURCE (Princeton)DNASE1L1
Genetics Home Reference (NIH)DNASE1L1
Genomic and cartography
GoldenPath hg19 (UCSC)DNASE1L1  -     chrX:153629577-153640428 -  Xq28   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DNASE1L1  -     Xq28   [Description]    (hg38-Dec_2013)
EnsemblDNASE1L1 - Xq28 [CytoView hg19]  DNASE1L1 - Xq28 [CytoView hg38]
Mapping of homologs : NCBIDNASE1L1 [Mapview hg19]  DNASE1L1 [Mapview hg38]
OMIM300081   
Gene and transcription
Genbank (Entrez)AL079680 AM392815 AW445150 BC001561 BC028092
RefSeq transcript (Entrez)NM_001009932 NM_001009933 NM_001009934 NM_001303620 NM_006730
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_012884 NT_011681 NW_004929448
Consensus coding sequences : CCDS (NCBI)DNASE1L1
Cluster EST : UnigeneHs.534404 [ NCBI ]
CGAP (NCI)Hs.534404
Alternative Splicing GalleryENSG00000013563
Gene ExpressionDNASE1L1 [ NCBI-GEO ]   DNASE1L1 [ EBI - ARRAY_EXPRESS ]   DNASE1L1 [ SEEK ]   DNASE1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNASE1L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1774
GTEX Portal (Tissue expression)DNASE1L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49184   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49184  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49184
Splice isoforms : SwissVarP49184
Catalytic activity : Enzyme3.1.21.- [ Enzyme-Expasy ]   3.1.21.-3.1.21.- [ IntEnz-EBI ]   3.1.21.- [ BRENDA ]   3.1.21.- [ KEGG ]   
PhosPhoSitePlusP49184
Domaine pattern : Prosite (Expaxy)DNASE_I_1 (PS00919)    DNASE_I_2 (PS00918)   
Domains : Interpro (EBI)Deoxyribonuclease-1_AS    DNase_I    DNASE_I_2    Endo/exonuclease/phosphatase   
Domain families : Pfam (Sanger)Exo_endo_phos (PF03372)   
Domain families : Pfam (NCBI)pfam03372   
Domain families : Smart (EMBL)DNaseIc (SM00476)  
Conserved Domain (NCBI)DNASE1L1
DMDM Disease mutations1774
Blocks (Seattle)DNASE1L1
SuperfamilyP49184
Human Protein AtlasENSG00000013563
Peptide AtlasP49184
HPRD02096
IPIIPI00026125   IPI00643217   IPI00853347   IPI00852887   IPI00877780   IPI00877931   
Protein Interaction databases
DIP (DOE-UCLA)P49184
IntAct (EBI)P49184
FunCoupENSG00000013563
BioGRIDDNASE1L1
STRING (EMBL)DNASE1L1
ZODIACDNASE1L1
Ontologies - Pathways
QuickGOP49184
Ontology : AmiGODNA binding  endonuclease activity  deoxyribonuclease activity  nucleus  endoplasmic reticulum  DNA metabolic process  DNA catabolic process  extracellular exosome  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIDNA binding  endonuclease activity  deoxyribonuclease activity  nucleus  endoplasmic reticulum  DNA metabolic process  DNA catabolic process  extracellular exosome  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkDNASE1L1
Atlas of Cancer Signalling NetworkDNASE1L1
Wikipedia pathwaysDNASE1L1
Orthology - Evolution
OrthoDB1774
GeneTree (enSembl)ENSG00000013563
Phylogenetic Trees/Animal Genes : TreeFamDNASE1L1
HOVERGENP49184
HOGENOMP49184
Homologs : HomoloGeneDNASE1L1
Homology/Alignments : Family Browser (UCSC)DNASE1L1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNASE1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNASE1L1
dbVarDNASE1L1
ClinVarDNASE1L1
1000_GenomesDNASE1L1 
Exome Variant ServerDNASE1L1
ExAC (Exome Aggregation Consortium)DNASE1L1 (select the gene name)
Genetic variants : HAPMAP1774
Genomic Variants (DGV)DNASE1L1 [DGVbeta]
DECIPHER (Syndromes)X:153629577-153640428  ENSG00000013563
CONAN: Copy Number AnalysisDNASE1L1 
Mutations
ICGC Data PortalDNASE1L1 
TCGA Data PortalDNASE1L1 
Broad Tumor PortalDNASE1L1
OASIS PortalDNASE1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNASE1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNASE1L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DNASE1L1
DgiDB (Drug Gene Interaction Database)DNASE1L1
DoCM (Curated mutations)DNASE1L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNASE1L1 (select a term)
intoGenDNASE1L1
Cancer3DDNASE1L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300081   
Orphanet
MedgenDNASE1L1
Genetic Testing Registry DNASE1L1
NextProtP49184 [Medical]
TSGene1774
GENETestsDNASE1L1
Huge Navigator DNASE1L1 [HugePedia]
snp3D : Map Gene to Disease1774
BioCentury BCIQDNASE1L1
ClinGenDNASE1L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1774
Chemical/Pharm GKB GenePA27428
Clinical trialDNASE1L1
Miscellaneous
canSAR (ICR)DNASE1L1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNASE1L1
EVEXDNASE1L1
GoPubMedDNASE1L1
iHOPDNASE1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:03:38 CET 2017

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