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DNER (delta/notch like EGF repeat containing)

Identity

Alias (NCBI)UNQ26
bet
HGNC (Hugo) DNER
HGNC Alias symbUNQ26
bet
HGNC Previous namedelta/notch-like EGF repeat containing
LocusID (NCBI) 92737
Atlas_Id 53665
Location 2q36.3  [Link to chromosome band 2q36]
Location_base_pair Starts at 229357629 and ends at 229714555 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNER (2q36.3) / ELL2 (5q15)DNER (2q36.3) / TRIP12 (2q36.3)PID1 (2q36.3) / DNER (2q36.3)
PSMD1 (2q37.1) / DNER (2q36.3)UNC13B (9p13.3) / DNER (2q36.3)DNER 2q36.3 / TRIP12 2q36.3
PID1 2q36.3 / DNER 2q36.3PSMD1 2q37.1 / DNER 2q36.3UNC13B 9p13.3 / DNER 2q36.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DNER   24456
Cards
Entrez_Gene (NCBI)DNER    delta/notch like EGF repeat containing
AliasesUNQ26; bet
GeneCards (Weizmann)DNER
Ensembl hg19 (Hinxton)ENSG00000187957 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187957 [Gene_View]  ENSG00000187957 [Sequence]  chr2:229357629-229714555 [Contig_View]  DNER [Vega]
ICGC DataPortalENSG00000187957
TCGA cBioPortalDNER
AceView (NCBI)DNER
Genatlas (Paris)DNER
SOURCE (Princeton)DNER
Genetics Home Reference (NIH)DNER
Genomic and cartography
GoldenPath hg38 (UCSC)DNER  -     chr2:229357629-229714555 -  2q36.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNER  -     2q36.3   [Description]    (hg19-Feb_2009)
GoldenPathDNER - 2q36.3 [CytoView hg19]  DNER - 2q36.3 [CytoView hg38]
ImmunoBaseENSG00000187957
Genome Data Viewer NCBIDNER [Mapview hg19]  
OMIM607299   
Gene and transcription
Genbank (Entrez)AF442487 AK289553 AK304596 AK304631 AK308576
RefSeq transcript (Entrez)NM_139072
Consensus coding sequences : CCDS (NCBI)DNER
Gene ExpressionDNER [ NCBI-GEO ]   DNER [ EBI - ARRAY_EXPRESS ]   DNER [ SEEK ]   DNER [ MEM ]
Gene Expression Viewer (FireBrowse)DNER [ Firebrowse - Broad ]
GenevisibleExpression of DNER in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92737
GTEX Portal (Tissue expression)DNER
Human Protein AtlasENSG00000187957-DNER [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFT8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFT8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFT8
PhosPhoSitePlusQ8NFT8
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)   
Domains : Interpro (EBI)EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    Growth_fac_rcpt_cys_sf   
Domain families : Pfam (Sanger)EGF (PF00008)    hEGF (PF12661)   
Domain families : Pfam (NCBI)pfam00008    pfam12661   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
Conserved Domain (NCBI)DNER
SuperfamilyQ8NFT8
AlphaFold pdb e-kbQ8NFT8   
Human Protein Atlas [tissue]ENSG00000187957-DNER [tissue]
HPRD09531
Protein Interaction databases
DIP (DOE-UCLA)Q8NFT8
IntAct (EBI)Q8NFT8
BioGRIDDNER
STRING (EMBL)DNER
ZODIACDNER
Ontologies - Pathways
QuickGOQ8NFT8
Ontology : AmiGOneuron migration  transmembrane signaling receptor activity  Notch binding  calcium ion binding  protein binding  early endosome  plasma membrane  endocytosis  Notch signaling pathway  Notch receptor processing  synapse assembly  central nervous system development  glial cell differentiation  integral component of membrane  clathrin binding  dendrite  neuronal cell body  skeletal muscle fiber development  
Ontology : EGO-EBIneuron migration  transmembrane signaling receptor activity  Notch binding  calcium ion binding  protein binding  early endosome  plasma membrane  endocytosis  Notch signaling pathway  Notch receptor processing  synapse assembly  central nervous system development  glial cell differentiation  integral component of membrane  clathrin binding  dendrite  neuronal cell body  skeletal muscle fiber development  
NDEx NetworkDNER
Atlas of Cancer Signalling NetworkDNER
Wikipedia pathwaysDNER
Orthology - Evolution
OrthoDB92737
GeneTree (enSembl)ENSG00000187957
Phylogenetic Trees/Animal Genes : TreeFamDNER
Homologs : HomoloGeneDNER
Homology/Alignments : Family Browser (UCSC)DNER
Gene fusions - Rearrangements
Fusion : MitelmanDNER/TRIP12 [2q36.3/2q36.3]  
Fusion : MitelmanPID1/DNER [2q36.3/2q36.3]  
Fusion : MitelmanPSMD1/DNER [2q37.1/2q36.3]  
Fusion : MitelmanUNC13B/DNER [9p13.3/2q36.3]  
Fusion : QuiverDNER
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNER [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNER
dbVarDNER
ClinVarDNER
MonarchDNER
1000_GenomesDNER 
Exome Variant ServerDNER
GNOMAD BrowserENSG00000187957
Varsome BrowserDNER
ACMGDNER variants
VarityQ8NFT8
Genomic Variants (DGV)DNER [DGVbeta]
DECIPHERDNER [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNER 
Mutations
ICGC Data PortalDNER 
TCGA Data PortalDNER 
Broad Tumor PortalDNER
OASIS PortalDNER [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNER  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNER
Mutations and Diseases : HGMDDNER
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDNER
DgiDB (Drug Gene Interaction Database)DNER
DoCM (Curated mutations)DNER
CIViC (Clinical Interpretations of Variants in Cancer)DNER
Cancer3DDNER
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607299   
Orphanet
DisGeNETDNER
MedgenDNER
Genetic Testing Registry DNER
NextProtQ8NFT8 [Medical]
GENETestsDNER
Target ValidationDNER
Huge Navigator DNER [HugePedia]
ClinGenDNER
Clinical trials, drugs, therapy
MyCancerGenomeDNER
Protein Interactions : CTDDNER
Pharm GKB GenePA162383959
PharosQ8NFT8
Clinical trialDNER
Miscellaneous
canSAR (ICR)DNER
HarmonizomeDNER
DataMed IndexDNER
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDNER
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:07:07 CEST 2021

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