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DNER (delta/notch like EGF repeat containing)

Identity

Alias_namesdelta/notch-like EGF repeat containing
Alias_symbol (synonym)UNQ26
bet
Other alias
HGNC (Hugo) DNER
LocusID (NCBI) 92737
Atlas_Id 53665
Location 2q36.3  [Link to chromosome band 2q36]
Location_base_pair Starts at 229357629 and ends at 229714570 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DNER (2q36.3) / ELL2 (5q15)DNER (2q36.3) / TRIP12 (2q36.3)PID1 (2q36.3) / DNER (2q36.3)
PSMD1 (2q37.1) / DNER (2q36.3)UNC13B (9p13.3) / DNER (2q36.3)DNER 2q36.3 / TRIP12 2q36.3
PID1 2q36.3 / DNER 2q36.3PSMD1 2q37.1 / DNER 2q36.3UNC13B 9p13.3 / DNER 2q36.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNER   24456
Cards
Entrez_Gene (NCBI)DNER  92737  delta/notch like EGF repeat containing
AliasesUNQ26; bet
GeneCards (Weizmann)DNER
Ensembl hg19 (Hinxton)ENSG00000187957 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187957 [Gene_View]  chr2:229357629-229714570 [Contig_View]  DNER [Vega]
ICGC DataPortalENSG00000187957
TCGA cBioPortalDNER
AceView (NCBI)DNER
Genatlas (Paris)DNER
WikiGenes92737
SOURCE (Princeton)DNER
Genetics Home Reference (NIH)DNER
Genomic and cartography
GoldenPath hg38 (UCSC)DNER  -     chr2:229357629-229714570 -  2q36.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNER  -     2q36.3   [Description]    (hg19-Feb_2009)
EnsemblDNER - 2q36.3 [CytoView hg19]  DNER - 2q36.3 [CytoView hg38]
Mapping of homologs : NCBIDNER [Mapview hg19]  DNER [Mapview hg38]
OMIM607299   
Gene and transcription
Genbank (Entrez)AF442487 AK289553 AK304596 AK304631 AK308576
RefSeq transcript (Entrez)NM_139072
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNER
Cluster EST : UnigeneHs.234074 [ NCBI ]
CGAP (NCI)Hs.234074
Alternative Splicing GalleryENSG00000187957
Gene ExpressionDNER [ NCBI-GEO ]   DNER [ EBI - ARRAY_EXPRESS ]   DNER [ SEEK ]   DNER [ MEM ]
Gene Expression Viewer (FireBrowse)DNER [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92737
GTEX Portal (Tissue expression)DNER
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFT8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFT8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFT8
Splice isoforms : SwissVarQ8NFT8
PhosPhoSitePlusQ8NFT8
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)   
Domains : Interpro (EBI)EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    Growth_fac_rcpt_   
Domain families : Pfam (Sanger)EGF (PF00008)    hEGF (PF12661)   
Domain families : Pfam (NCBI)pfam00008    pfam12661   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
Conserved Domain (NCBI)DNER
DMDM Disease mutations92737
Blocks (Seattle)DNER
SuperfamilyQ8NFT8
Human Protein AtlasENSG00000187957
Peptide AtlasQ8NFT8
HPRD09531
IPIIPI00333140   IPI01012713   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFT8
IntAct (EBI)Q8NFT8
FunCoupENSG00000187957
BioGRIDDNER
STRING (EMBL)DNER
ZODIACDNER
Ontologies - Pathways
QuickGOQ8NFT8
Ontology : AmiGOneuron migration  transmembrane signaling receptor activity  Notch binding  calcium ion binding  protein binding  early endosome  plasma membrane  endocytosis  Notch signaling pathway  Notch receptor processing  synapse assembly  central nervous system development  glial cell differentiation  integral component of membrane  clathrin binding  dendrite  neuronal cell body  skeletal muscle fiber development  
Ontology : EGO-EBIneuron migration  transmembrane signaling receptor activity  Notch binding  calcium ion binding  protein binding  early endosome  plasma membrane  endocytosis  Notch signaling pathway  Notch receptor processing  synapse assembly  central nervous system development  glial cell differentiation  integral component of membrane  clathrin binding  dendrite  neuronal cell body  skeletal muscle fiber development  
NDEx NetworkDNER
Atlas of Cancer Signalling NetworkDNER
Wikipedia pathwaysDNER
Orthology - Evolution
OrthoDB92737
GeneTree (enSembl)ENSG00000187957
Phylogenetic Trees/Animal Genes : TreeFamDNER
HOVERGENQ8NFT8
HOGENOMQ8NFT8
Homologs : HomoloGeneDNER
Homology/Alignments : Family Browser (UCSC)DNER
Gene fusions - Rearrangements
Fusion : MitelmanDNER/TRIP12 [2q36.3/2q36.3]  
Fusion : MitelmanPID1/DNER [2q36.3/2q36.3]  [t(2;2)(q36;q36)]  
Fusion : MitelmanPSMD1/DNER [2q37.1/2q36.3]  [t(2;2)(q36;q37)]  
Fusion : MitelmanUNC13B/DNER [9p13.3/2q36.3]  [t(2;9)(q36;p13)]  
Fusion: TCGADNER 2q36.3 TRIP12 2q36.3 BRCA
Fusion: TCGAPID1 2q36.3 DNER 2q36.3 LUAD
Fusion: TCGAPSMD1 2q37.1 DNER 2q36.3 GBM
Fusion: TCGAUNC13B 9p13.3 DNER 2q36.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNER [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNER
dbVarDNER
ClinVarDNER
1000_GenomesDNER 
Exome Variant ServerDNER
ExAC (Exome Aggregation Consortium)DNER (select the gene name)
Genetic variants : HAPMAP92737
Genomic Variants (DGV)DNER [DGVbeta]
DECIPHERDNER [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNER 
Mutations
ICGC Data PortalDNER 
TCGA Data PortalDNER 
Broad Tumor PortalDNER
OASIS PortalDNER [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNER  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNER
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNER
DgiDB (Drug Gene Interaction Database)DNER
DoCM (Curated mutations)DNER (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNER (select a term)
intoGenDNER
Cancer3DDNER(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607299   
Orphanet
MedgenDNER
Genetic Testing Registry DNER
NextProtQ8NFT8 [Medical]
TSGene92737
GENETestsDNER
Target ValidationDNER
Huge Navigator DNER [HugePedia]
snp3D : Map Gene to Disease92737
BioCentury BCIQDNER
ClinGenDNER
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92737
Chemical/Pharm GKB GenePA162383959
Clinical trialDNER
Miscellaneous
canSAR (ICR)DNER (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNER
EVEXDNER
GoPubMedDNER
iHOPDNER
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:31:32 CEST 2017

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