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DNM1 (dynamin 1)

Identity

Alias (NCBI)DEE31
DNM
EIEE31
HGNC (Hugo) DNM1
HGNC Previous nameDNM
LocusID (NCBI) 1759
Atlas_Id 40346
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 128203379 and ends at 128255244 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COQ4 (9q34.11)::DNM1 (9q34.11)DNM1 (9q34.11)::LCN2 (9q34.11)DNM1 (9q34.11)::TRIO (5p15.2)
COQ4 9q34.11::DNM1 9q34.11DNM1 9q34.11::LCN2 9q34.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DNM1   2972
Cards
Entrez_Gene (NCBI)DNM1    dynamin 1
AliasesDEE31; DNM; EIEE31
GeneCards (Weizmann)DNM1
Ensembl hg19 (Hinxton)ENSG00000106976 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106976 [Gene_View]  ENSG00000106976 [Sequence]  chr9:128203379-128255244 [Contig_View]  DNM1 [Vega]
ICGC DataPortalENSG00000106976
TCGA cBioPortalDNM1
AceView (NCBI)DNM1
Genatlas (Paris)DNM1
SOURCE (Princeton)DNM1
Genetics Home Reference (NIH)DNM1
Genomic and cartography
GoldenPath hg38 (UCSC)DNM1  -     chr9:128203379-128255244 +  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNM1  -     9q34.11   [Description]    (hg19-Feb_2009)
GoldenPathDNM1 - 9q34.11 [CytoView hg19]  DNM1 - 9q34.11 [CytoView hg38]
ImmunoBaseENSG00000106976
Genome Data Viewer NCBIDNM1 [Mapview hg19]  
OMIM602377   616346   
Gene and transcription
Genbank (Entrez)AB209124 AF035321 AI660320 AK096629 AK127038
RefSeq transcript (Entrez)NM_001005336 NM_001288737 NM_001288738 NM_001288739 NM_001374269 NM_004408
Consensus coding sequences : CCDS (NCBI)DNM1
Gene ExpressionDNM1 [ NCBI-GEO ]   DNM1 [ EBI - ARRAY_EXPRESS ]   DNM1 [ SEEK ]   DNM1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNM1 [ Firebrowse - Broad ]
GenevisibleExpression of DNM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1759
GTEX Portal (Tissue expression)DNM1
Human Protein AtlasENSG00000106976-DNM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05193   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ05193  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ05193
PhosPhoSitePlusQ05193
Domaine pattern : Prosite (Expaxy)G_DYNAMIN_1 (PS00410)    G_DYNAMIN_2 (PS51718)    GED (PS51388)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)DNM1    Dynamin_GTPase    Dynamin_GTPase_CS    Dynamin_SF    Dynamin_stalk    G_DYNAMIN_dom    GED    GED_dom    P-loop_NTPase    PH-like_dom_sf    PH_domain   
Domain families : Pfam (Sanger)Dynamin_M (PF01031)    Dynamin_N (PF00350)    GED (PF02212)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01031    pfam00350    pfam02212    pfam00169   
Domain families : Smart (EMBL)DYNc (SM00053)  GED (SM00302)  PH (SM00233)  
Conserved Domain (NCBI)DNM1
PDB (RSDB)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
PDB Europe1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
PDB (PDBSum)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
PDB (IMB)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
Structural Biology KnowledgeBase1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
SCOP (Structural Classification of Proteins)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
CATH (Classification of proteins structures)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q    6DLU    6DLV    6S9A   
SuperfamilyQ05193
AlphaFold pdb e-kbQ05193   
Human Protein Atlas [tissue]ENSG00000106976-DNM1 [tissue]
HPRD03851
Protein Interaction databases
DIP (DOE-UCLA)Q05193
IntAct (EBI)Q05193
BioGRIDDNM1
STRING (EMBL)DNM1
ZODIACDNM1
Ontologies - Pathways
QuickGOQ05193
Ontology : AmiGOphotoreceptor inner segment  RNA binding  GTPase activity  protein binding  GTP binding  nucleoplasm  cytoplasm  microtubule  plasma membrane  plasma membrane  endocytosis  endocytosis  receptor-mediated endocytosis  endosome organization  microtubule binding  membrane  synaptic vesicle budding from presynaptic endocytic zone membrane  protein kinase binding  membrane coat  receptor internalization  identical protein binding  synapse  synaptic vesicle endocytosis  modulation of chemical synaptic transmission  extracellular exosome  photoreceptor ribbon synapse  presynaptic endocytic zone membrane  glutamatergic synapse  toxin transport  
Ontology : EGO-EBIphotoreceptor inner segment  RNA binding  GTPase activity  protein binding  GTP binding  nucleoplasm  cytoplasm  microtubule  plasma membrane  plasma membrane  endocytosis  endocytosis  receptor-mediated endocytosis  endosome organization  microtubule binding  membrane  synaptic vesicle budding from presynaptic endocytic zone membrane  protein kinase binding  membrane coat  receptor internalization  identical protein binding  synapse  synaptic vesicle endocytosis  modulation of chemical synaptic transmission  extracellular exosome  photoreceptor ribbon synapse  presynaptic endocytic zone membrane  glutamatergic synapse  toxin transport  
Pathways : BIOCARTABIOCARTA_NDKDYNAMINPATHWAY    BIOCARTA_BARR_MAPKPATHWAY    BIOCARTA_BARRESTIN_SRCPATHWAY    BIOCARTA_BARRESTINPATHWAY   
Pathways : KEGGKEGG_ENDOCYTOSIS    KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS   
NDEx NetworkDNM1
Atlas of Cancer Signalling NetworkDNM1
Wikipedia pathwaysDNM1
Orthology - Evolution
OrthoDB1759
GeneTree (enSembl)ENSG00000106976
Phylogenetic Trees/Animal Genes : TreeFamDNM1
Homologs : HomoloGeneDNM1
Homology/Alignments : Family Browser (UCSC)DNM1
Gene fusions - Rearrangements
Fusion : MitelmanCOQ4::DNM1 [9q34.11/9q34.11]  
Fusion : MitelmanDNM1::LCN2 [9q34.11/9q34.11]  
Fusion : QuiverDNM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNM1
dbVarDNM1
ClinVarDNM1
MonarchDNM1
1000_GenomesDNM1 
Exome Variant ServerDNM1
GNOMAD BrowserENSG00000106976
Varsome BrowserDNM1
ACMGDNM1 variants
VarityQ05193
Genomic Variants (DGV)DNM1 [DGVbeta]
DECIPHERDNM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNM1 
Mutations
ICGC Data PortalDNM1 
TCGA Data PortalDNM1 
Broad Tumor PortalDNM1
OASIS PortalDNM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNM1
Mutations and Diseases : HGMDDNM1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDNM1
DgiDB (Drug Gene Interaction Database)DNM1
DoCM (Curated mutations)DNM1
CIViC (Clinical Interpretations of Variants in Cancer)DNM1
Cancer3DDNM1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602377    616346   
Orphanet885    23427   
DisGeNETDNM1
MedgenDNM1
Genetic Testing Registry DNM1
NextProtQ05193 [Medical]
GENETestsDNM1
Target ValidationDNM1
Huge Navigator DNM1 [HugePedia]
ClinGenDNM1
Clinical trials, drugs, therapy
MyCancerGenomeDNM1
Protein Interactions : CTDDNM1
Pharm GKB GenePA27440
PharosQ05193
Clinical trialDNM1
Miscellaneous
canSAR (ICR)DNM1
HarmonizomeDNM1
ARCHS4DNM1
DataMed IndexDNM1
Probes
Litterature
PubMed180 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDNM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:31:00 CET 2022

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