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DNM1 (dynamin 1)

Identity

Alias_namesDNM
Other aliasEIEE31
HGNC (Hugo) DNM1
LocusID (NCBI) 1759
Atlas_Id 40346
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 128203355 and ends at 128255248 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COQ4 (9q34.11) / DNM1 (9q34.11)DNM1 (9q34.11) / LCN2 (9q34.11)DNM1 (9q34.11) / TRIO (5p15.2)
COQ4 9q34.11 / DNM1 9q34.11DNM1 9q34.11 / LCN2 9q34.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNM1   2972
Cards
Entrez_Gene (NCBI)DNM1  1759  dynamin 1
AliasesDNM; EIEE31
GeneCards (Weizmann)DNM1
Ensembl hg19 (Hinxton)ENSG00000106976 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106976 [Gene_View]  chr9:128203355-128255248 [Contig_View]  DNM1 [Vega]
ICGC DataPortalENSG00000106976
TCGA cBioPortalDNM1
AceView (NCBI)DNM1
Genatlas (Paris)DNM1
WikiGenes1759
SOURCE (Princeton)DNM1
Genetics Home Reference (NIH)DNM1
Genomic and cartography
GoldenPath hg38 (UCSC)DNM1  -     chr9:128203355-128255248 +  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNM1  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblDNM1 - 9q34.11 [CytoView hg19]  DNM1 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIDNM1 [Mapview hg19]  DNM1 [Mapview hg38]
OMIM602377   616346   
Gene and transcription
Genbank (Entrez)AB209124 AF035321 AI660320 AK096629 AK127038
RefSeq transcript (Entrez)NM_001005336 NM_001288737 NM_001288738 NM_001288739 NM_004408
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNM1
Cluster EST : UnigeneHs.522413 [ NCBI ]
CGAP (NCI)Hs.522413
Alternative Splicing GalleryENSG00000106976
Gene ExpressionDNM1 [ NCBI-GEO ]   DNM1 [ EBI - ARRAY_EXPRESS ]   DNM1 [ SEEK ]   DNM1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1759
GTEX Portal (Tissue expression)DNM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05193   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ05193  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ05193
Splice isoforms : SwissVarQ05193
PhosPhoSitePlusQ05193
Domaine pattern : Prosite (Expaxy)G_DYNAMIN_1 (PS00410)    G_DYNAMIN_2 (PS51718)    GED (PS51388)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)DNM1    Dynamin_central    Dynamin_GTPase    Dynamin_GTPase_CS    Dynamin_SF    G_DYNAMIN_dom    GED    GED_dom    P-loop_NTPase    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Dynamin_M (PF01031)    Dynamin_N (PF00350)    GED (PF02212)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01031    pfam00350    pfam02212    pfam00169   
Domain families : Smart (EMBL)DYNc (SM00053)  GED (SM00302)  PH (SM00233)  
Conserved Domain (NCBI)DNM1
DMDM Disease mutations1759
Blocks (Seattle)DNM1
PDB (SRS)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
PDB (PDBSum)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
PDB (IMB)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
PDB (RSDB)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
Structural Biology KnowledgeBase1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
SCOP (Structural Classification of Proteins)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
CATH (Classification of proteins structures)1DYN    2DYN    2X2E    2X2F    3SNH    3ZYC    3ZYS    4UUD    4UUK    5D3Q   
SuperfamilyQ05193
Human Protein AtlasENSG00000106976
Peptide AtlasQ05193
HPRD03851
IPIIPI00413140   IPI00887273   IPI00816287   IPI00888758   IPI00657691   IPI01011821   IPI01008863   IPI00947325   
Protein Interaction databases
DIP (DOE-UCLA)Q05193
IntAct (EBI)Q05193
FunCoupENSG00000106976
BioGRIDDNM1
STRING (EMBL)DNM1
ZODIACDNM1
Ontologies - Pathways
QuickGOQ05193
Ontology : AmiGOmitochondrial fission  photoreceptor inner segment  G-protein coupled receptor internalization  dynamin family protein polymerization involved in mitochondrial fission  RNA binding  GTPase activity  protein binding  GTP binding  Golgi apparatus  microtubule  plasma membrane  endocytosis  endocytosis  receptor-mediated endocytosis  endosome organization  sensory perception of sound  microtubule binding  synaptic vesicle  protein C-terminus binding  adult locomotory behavior  synaptic vesicle budding from presynaptic endocytic zone membrane  protein kinase binding  membrane coat  D2 dopamine receptor binding  mitochondrial membrane  protein complex binding  identical protein binding  varicosity  myelin sheath  protein dimerization activity  ephrin receptor signaling pathway  nitric-oxide synthase binding  protein tetramerization  synaptic transmission, GABAergic  membrane fusion  extracellular exosome  toxin transport  positive regulation of synaptic vesicle recycling  
Ontology : EGO-EBImitochondrial fission  photoreceptor inner segment  G-protein coupled receptor internalization  dynamin family protein polymerization involved in mitochondrial fission  RNA binding  GTPase activity  protein binding  GTP binding  Golgi apparatus  microtubule  plasma membrane  endocytosis  endocytosis  receptor-mediated endocytosis  endosome organization  sensory perception of sound  microtubule binding  synaptic vesicle  protein C-terminus binding  adult locomotory behavior  synaptic vesicle budding from presynaptic endocytic zone membrane  protein kinase binding  membrane coat  D2 dopamine receptor binding  mitochondrial membrane  protein complex binding  identical protein binding  varicosity  myelin sheath  protein dimerization activity  ephrin receptor signaling pathway  nitric-oxide synthase binding  protein tetramerization  synaptic transmission, GABAergic  membrane fusion  extracellular exosome  toxin transport  positive regulation of synaptic vesicle recycling  
Pathways : BIOCARTA [Genes]   
Pathways : KEGGEndocytosis    Synaptic vesicle cycle    Endocrine and other factor-regulated calcium reabsorption    Bacterial invasion of epithelial cells   
NDEx NetworkDNM1
Atlas of Cancer Signalling NetworkDNM1
Wikipedia pathwaysDNM1
Orthology - Evolution
OrthoDB1759
GeneTree (enSembl)ENSG00000106976
Phylogenetic Trees/Animal Genes : TreeFamDNM1
HOVERGENQ05193
HOGENOMQ05193
Homologs : HomoloGeneDNM1
Homology/Alignments : Family Browser (UCSC)DNM1
Gene fusions - Rearrangements
Fusion : MitelmanCOQ4/DNM1 [9q34.11/9q34.11]  [t(9;9)(q34;q34)]  
Fusion : MitelmanDNM1/LCN2 [9q34.11/9q34.11]  [t(9;9)(q34;q34)]  
Fusion: TCGACOQ4 9q34.11 DNM1 9q34.11 BRCA
Fusion: TCGADNM1 9q34.11 LCN2 9q34.11 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNM1
dbVarDNM1
ClinVarDNM1
1000_GenomesDNM1 
Exome Variant ServerDNM1
ExAC (Exome Aggregation Consortium)DNM1 (select the gene name)
Genetic variants : HAPMAP1759
Genomic Variants (DGV)DNM1 [DGVbeta]
DECIPHERDNM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNM1 
Mutations
ICGC Data PortalDNM1 
TCGA Data PortalDNM1 
Broad Tumor PortalDNM1
OASIS PortalDNM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNM1
DgiDB (Drug Gene Interaction Database)DNM1
DoCM (Curated mutations)DNM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNM1 (select a term)
intoGenDNM1
Cancer3DDNM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602377    616346   
Orphanet885    23427   
MedgenDNM1
Genetic Testing Registry DNM1
NextProtQ05193 [Medical]
TSGene1759
GENETestsDNM1
Target ValidationDNM1
Huge Navigator DNM1 [HugePedia]
snp3D : Map Gene to Disease1759
BioCentury BCIQDNM1
ClinGenDNM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1759
Chemical/Pharm GKB GenePA27440
Clinical trialDNM1
Miscellaneous
canSAR (ICR)DNM1 (select the gene name)
Probes
Litterature
PubMed155 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNM1
EVEXDNM1
GoPubMedDNM1
iHOPDNM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:59:47 CEST 2017

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