Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DNM3 (dynamin 3)

Identity

Alias_symbol (synonym)KIAA0820
Other aliasDyna III
HGNC (Hugo) DNM3
LocusID (NCBI) 26052
Atlas_Id 54259
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 171810618 and ends at 172381857 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DNM3 (1q24.3) / RFWD2 (1q25.1)JKAMP (14q23.1) / DNM3 (1q24.3)METTL13 (1q24.3) / DNM3 (1q24.3)
MIER1 (1p31.3) / DNM3 (1q24.3)PFN1 (17p13.2) / DNM3 (1q24.3)SUCO (1q24.3) / DNM3 (1q24.3)
C1orf9 DNM3 1q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNM3   29125
Cards
Entrez_Gene (NCBI)DNM3  26052  dynamin 3
AliasesDyna
GeneCards (Weizmann)DNM3
Ensembl hg19 (Hinxton)ENSG00000197959 [Gene_View]  chr1:171810618-172381857 [Contig_View]  DNM3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197959 [Gene_View]  chr1:171810618-172381857 [Contig_View]  DNM3 [Vega]
ICGC DataPortalENSG00000197959
TCGA cBioPortalDNM3
AceView (NCBI)DNM3
Genatlas (Paris)DNM3
WikiGenes26052
SOURCE (Princeton)DNM3
Genetics Home Reference (NIH)DNM3
Genomic and cartography
GoldenPath hg19 (UCSC)DNM3  -     chr1:171810618-172381857 +  1q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DNM3  -     1q24.3   [Description]    (hg38-Dec_2013)
EnsemblDNM3 - 1q24.3 [CytoView hg19]  DNM3 - 1q24.3 [CytoView hg38]
Mapping of homologs : NCBIDNM3 [Mapview hg19]  DNM3 [Mapview hg38]
OMIM611445   
Gene and transcription
Genbank (Entrez)AB020627 AK056279 AK307806 AK308992 AL035110
RefSeq transcript (Entrez)NM_001136127 NM_001278252 NM_015569
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)DNM3
Cluster EST : UnigeneHs.654775 [ NCBI ]
CGAP (NCI)Hs.654775
Alternative Splicing GalleryENSG00000197959
Gene ExpressionDNM3 [ NCBI-GEO ]   DNM3 [ EBI - ARRAY_EXPRESS ]   DNM3 [ SEEK ]   DNM3 [ MEM ]
Gene Expression Viewer (FireBrowse)DNM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26052
GTEX Portal (Tissue expression)DNM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQ16   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQ16  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQ16
Splice isoforms : SwissVarQ9UQ16
Catalytic activity : Enzyme3.6.5.5 [ Enzyme-Expasy ]   3.6.5.53.6.5.5 [ IntEnz-EBI ]   3.6.5.5 [ BRENDA ]   3.6.5.5 [ KEGG ]   
PhosPhoSitePlusQ9UQ16
Domaine pattern : Prosite (Expaxy)G_DYNAMIN_1 (PS00410)    G_DYNAMIN_2 (PS51718)    GED (PS51388)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)Dynamin_central    Dynamin_GTPase    Dynamin_GTPase_CS    Dynamin_SF    G_DYNAMIN_dom    GED    GED_dom    P-loop_NTPase    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)Dynamin_M (PF01031)    Dynamin_N (PF00350)    GED (PF02212)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam01031    pfam00350    pfam02212    pfam00169   
Domain families : Smart (EMBL)DYNc (SM00053)  GED (SM00302)  PH (SM00233)  
Conserved Domain (NCBI)DNM3
DMDM Disease mutations26052
Blocks (Seattle)DNM3
PDB (SRS)3L43    5A3F   
PDB (PDBSum)3L43    5A3F   
PDB (IMB)3L43    5A3F   
PDB (RSDB)3L43    5A3F   
Structural Biology KnowledgeBase3L43    5A3F   
SCOP (Structural Classification of Proteins)3L43    5A3F   
CATH (Classification of proteins structures)3L43    5A3F   
SuperfamilyQ9UQ16
Human Protein AtlasENSG00000197959
Peptide AtlasQ9UQ16
HPRD13241
IPIIPI00221332   IPI00480085   IPI00977141   IPI00895844   IPI00641436   IPI00914615   IPI00975639   IPI00980135   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQ16
IntAct (EBI)Q9UQ16
FunCoupENSG00000197959
BioGRIDDNM3
STRING (EMBL)DNM3
ZODIACDNM3
Ontologies - Pathways
QuickGOQ9UQ16
Ontology : AmiGOphotoreceptor inner segment  GTPase activity  protein binding  GTP binding  mitochondrion  Golgi apparatus  microtubule  endocytosis  synapse assembly  metabolic process  postsynaptic density  axon  type 1 metabotropic glutamate receptor binding  type 5 metabotropic glutamate receptor binding  synaptic cleft  dendritic spine  dendritic spine head  filopodium assembly  perinuclear region of cytoplasm  nitric-oxide synthase binding  positive regulation of filopodium assembly  negative regulation of dendritic spine morphogenesis  extracellular exosome  
Ontology : EGO-EBIphotoreceptor inner segment  GTPase activity  protein binding  GTP binding  mitochondrion  Golgi apparatus  microtubule  endocytosis  synapse assembly  metabolic process  postsynaptic density  axon  type 1 metabotropic glutamate receptor binding  type 5 metabotropic glutamate receptor binding  synaptic cleft  dendritic spine  dendritic spine head  filopodium assembly  perinuclear region of cytoplasm  nitric-oxide synthase binding  positive regulation of filopodium assembly  negative regulation of dendritic spine morphogenesis  extracellular exosome  
Pathways : KEGGEndocytosis    Synaptic vesicle cycle    Endocrine and other factor-regulated calcium reabsorption    Bacterial invasion of epithelial cells   
NDEx NetworkDNM3
Atlas of Cancer Signalling NetworkDNM3
Wikipedia pathwaysDNM3
Orthology - Evolution
OrthoDB26052
GeneTree (enSembl)ENSG00000197959
Phylogenetic Trees/Animal Genes : TreeFamDNM3
HOVERGENQ9UQ16
HOGENOMQ9UQ16
Homologs : HomoloGeneDNM3
Homology/Alignments : Family Browser (UCSC)DNM3
Gene fusions - Rearrangements
Fusion : MitelmanMETTL13/DNM3 [1q24.3/1q24.3]  [del(1)(q24q24)]  
Fusion : MitelmanSUCO/DNM3 [1q24.3/1q24.3]  [t(1;1)(q24;q24)]  
Fusion: TCGAC1orf9 DNM3 1q24.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNM3
dbVarDNM3
ClinVarDNM3
1000_GenomesDNM3 
Exome Variant ServerDNM3
ExAC (Exome Aggregation Consortium)DNM3 (select the gene name)
Genetic variants : HAPMAP26052
Genomic Variants (DGV)DNM3 [DGVbeta]
DECIPHER (Syndromes)1:171810618-172381857  ENSG00000197959
CONAN: Copy Number AnalysisDNM3 
Mutations
ICGC Data PortalDNM3 
TCGA Data PortalDNM3 
Broad Tumor PortalDNM3
OASIS PortalDNM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNM3
DgiDB (Drug Gene Interaction Database)DNM3
DoCM (Curated mutations)DNM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNM3 (select a term)
intoGenDNM3
Cancer3DDNM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611445   
Orphanet
MedgenDNM3
Genetic Testing Registry DNM3
NextProtQ9UQ16 [Medical]
TSGene26052
GENETestsDNM3
Huge Navigator DNM3 [HugePedia]
snp3D : Map Gene to Disease26052
BioCentury BCIQDNM3
ClinGenDNM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26052
Chemical/Pharm GKB GenePA134954683
Clinical trialDNM3
Miscellaneous
canSAR (ICR)DNM3 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNM3
EVEXDNM3
GoPubMedDNM3
iHOPDNM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:59:13 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.