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DNMBP (dynamin binding protein)

Identity

Alias_symbol (synonym)KIAA1010
Tuba
ARHGEF36
Other aliasTUBA
HGNC (Hugo) DNMBP
LocusID (NCBI) 23268
Atlas_Id 43231
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 99875571 and ends at 99930996 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		DNMBP (10q24.2) / LURAP1L (9p23)DNMBP (10q24.2) / PAPPA2 (1q25.2)DNMBP (10q24.2) / PER1 (17p13.1)
DNMBP (10q24.2) / TPTE2 (13q12.11)DNMBP 10q24.2 / TPTE2 13q12.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DNMBP   30373
Cards
Entrez_Gene (NCBI)DNMBP  23268  dynamin binding protein
AliasesARHGEF36; TUBA
GeneCards (Weizmann)DNMBP
Ensembl hg19 (Hinxton)ENSG00000107554 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107554 [Gene_View]  chr10:99875571-99930996 [Contig_View]  DNMBP [Vega]
ICGC DataPortalENSG00000107554
TCGA cBioPortalDNMBP
AceView (NCBI)DNMBP
Genatlas (Paris)DNMBP
WikiGenes23268
SOURCE (Princeton)DNMBP
Genetics Home Reference (NIH)DNMBP
Genomic and cartography
GoldenPath hg38 (UCSC)DNMBP  -     chr10:99875571-99930996 -  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNMBP  -     10q24.2   [Description]    (hg19-Feb_2009)
EnsemblDNMBP - 10q24.2 [CytoView hg19]  DNMBP - 10q24.2 [CytoView hg38]
Mapping of homologs : NCBIDNMBP [Mapview hg19]  DNMBP [Mapview hg38]
OMIM611282   
Gene and transcription
Genbank (Entrez)AA194064 AA771860 AB023227 AI023943 AK128576
RefSeq transcript (Entrez)NM_001318326 NM_001318327 NM_015221
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNMBP
Cluster EST : UnigeneHs.500771 [ NCBI ]
CGAP (NCI)Hs.500771
Alternative Splicing GalleryENSG00000107554
Gene ExpressionDNMBP [ NCBI-GEO ]   DNMBP [ EBI - ARRAY_EXPRESS ]   DNMBP [ SEEK ]   DNMBP [ MEM ]
Gene Expression Viewer (FireBrowse)DNMBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23268
GTEX Portal (Tissue expression)DNMBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6XZF7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6XZF7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6XZF7
Splice isoforms : SwissVarQ6XZF7
PhosPhoSitePlusQ6XZF7
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    DH_1 (PS00741)    DH_2 (PS50010)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom    DH-domain    GDS_CDC24_CS    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)BAR (PF03114)    RhoGEF (PF00621)    SH3_1 (PF00018)    SH3_2 (PF07653)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam03114    pfam00621    pfam00018    pfam07653    pfam14604   
Domain families : Smart (EMBL)BAR (SM00721)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)DNMBP
DMDM Disease mutations23268
Blocks (Seattle)DNMBP
PDB (SRS)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB (PDBSum)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB (IMB)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB (RSDB)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
Structural Biology KnowledgeBase1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
SCOP (Structural Classification of Proteins)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
CATH (Classification of proteins structures)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
SuperfamilyQ6XZF7
Human Protein AtlasENSG00000107554
Peptide AtlasQ6XZF7
HPRD10918
IPIIPI00174025   IPI00480148   IPI00873922   IPI01014969   IPI01011375   IPI00514447   
Protein Interaction databases
DIP (DOE-UCLA)Q6XZF7
IntAct (EBI)Q6XZF7
FunCoupENSG00000107554
BioGRIDDNMBP
STRING (EMBL)DNMBP
ZODIACDNMBP
Ontologies - Pathways
QuickGOQ6XZF7
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  protein binding  Golgi stack  cytoskeleton  small GTPase mediated signal transduction  cell junction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  synapse  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  protein binding  Golgi stack  cytoskeleton  small GTPase mediated signal transduction  cell junction  regulation of Rho protein signal transduction  positive regulation of GTPase activity  synapse  
NDEx NetworkDNMBP
Atlas of Cancer Signalling NetworkDNMBP
Wikipedia pathwaysDNMBP
Orthology - Evolution
OrthoDB23268
GeneTree (enSembl)ENSG00000107554
Phylogenetic Trees/Animal Genes : TreeFamDNMBP
HOVERGENQ6XZF7
HOGENOMQ6XZF7
Homologs : HomoloGeneDNMBP
Homology/Alignments : Family Browser (UCSC)DNMBP
Gene fusions - Rearrangements
Fusion : MitelmanDNMBP/TPTE2 [10q24.2/13q12.11]  
Fusion: TCGADNMBP 10q24.2 TPTE2 13q12.11 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNMBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNMBP
dbVarDNMBP
ClinVarDNMBP
1000_GenomesDNMBP 
Exome Variant ServerDNMBP
ExAC (Exome Aggregation Consortium)DNMBP (select the gene name)
Genetic variants : HAPMAP23268
Genomic Variants (DGV)DNMBP [DGVbeta]
DECIPHERDNMBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNMBP 
Mutations
ICGC Data PortalDNMBP 
TCGA Data PortalDNMBP 
Broad Tumor PortalDNMBP
OASIS PortalDNMBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNMBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDNMBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNMBP
DgiDB (Drug Gene Interaction Database)DNMBP
DoCM (Curated mutations)DNMBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNMBP (select a term)
intoGenDNMBP
Cancer3DDNMBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611282   
Orphanet
MedgenDNMBP
Genetic Testing Registry DNMBP
NextProtQ6XZF7 [Medical]
TSGene23268
GENETestsDNMBP
Target ValidationDNMBP
Huge Navigator DNMBP [HugePedia]
snp3D : Map Gene to Disease23268
BioCentury BCIQDNMBP
ClinGenDNMBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23268
Chemical/Pharm GKB GenePA134950706
Clinical trialDNMBP
Miscellaneous
canSAR (ICR)DNMBP (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNMBP
EVEXDNMBP
GoPubMedDNMBP
iHOPDNMBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:31:34 CEST 2017
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