Atlas of Genetics and Cytogenetics in Oncology and Haematology

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DNMBP (dynamin binding protein)

Identity

Alias (NCBI)ARHGEF36
CTRCT48
TUBA
HGNC (Hugo) DNMBP
HGNC Alias symbKIAA1010
Tuba
ARHGEF36
HGNC Alias namescaffold protein TUBA
LocusID (NCBI) 23268
Atlas_Id 43231
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 99875577 and ends at 100009947 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNMBP (10q24.2) / LURAP1L (9p23)DNMBP (10q24.2) / PAPPA2 (1q25.2)DNMBP (10q24.2) / PER1 (17p13.1)
DNMBP (10q24.2) / TPTE2 (13q12.11)DNMBP 10q24.2 / TPTE2 13q12.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;13)(q24;q12) DNMBP/TPTE2

External links

Nomenclature
HGNC (Hugo)DNMBP   30373
Cards
Entrez_Gene (NCBI)DNMBP  23268  dynamin binding protein
AliasesARHGEF36; CTRCT48; TUBA
GeneCards (Weizmann)DNMBP
Ensembl hg19 (Hinxton)ENSG00000107554 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107554 [Gene_View]  ENSG00000107554 [Sequence]  chr10:99875577-100009947 [Contig_View]  DNMBP [Vega]
ICGC DataPortalENSG00000107554
TCGA cBioPortalDNMBP
AceView (NCBI)DNMBP
Genatlas (Paris)DNMBP
WikiGenes23268
SOURCE (Princeton)DNMBP
Genetics Home Reference (NIH)DNMBP
Genomic and cartography
GoldenPath hg38 (UCSC)DNMBP  -     chr10:99875577-100009947 -  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNMBP  -     10q24.2   [Description]    (hg19-Feb_2009)
GoldenPathDNMBP - 10q24.2 [CytoView hg19]  DNMBP - 10q24.2 [CytoView hg38]
ImmunoBaseENSG00000107554
genome Data Viewer NCBIDNMBP [Mapview hg19]  
OMIM611282   618415   
Gene and transcription
Genbank (Entrez)AA194064 AA771860 AB023227 AI023943 AK128576
RefSeq transcript (Entrez)NM_001318326 NM_001318327 NM_015221
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNMBP
Alternative Splicing GalleryENSG00000107554
Gene ExpressionDNMBP [ NCBI-GEO ]   DNMBP [ EBI - ARRAY_EXPRESS ]   DNMBP [ SEEK ]   DNMBP [ MEM ]
Gene Expression Viewer (FireBrowse)DNMBP [ Firebrowse - Broad ]
GenevisibleExpression of DNMBP in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23268
GTEX Portal (Tissue expression)DNMBP
Human Protein AtlasENSG00000107554-DNMBP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6XZF7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6XZF7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6XZF7
Splice isoforms : SwissVarQ6XZF7
PhosPhoSitePlusQ6XZF7
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    DH_1 (PS00741)    DH_2 (PS50010)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR_dom_sf    BAR_dom    DBL_dom_sf    DH-domain    DNMBP    DNMBP_SH3_C1    DNMBP_SH3_N1    DNMBP_SH3_N2    DNMBP_SH3_N3    GDS_CDC24_CS    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)BAR (PF03114)    RhoGEF (PF00621)    SH3_1 (PF00018)    SH3_2 (PF07653)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam03114    pfam00621    pfam00018    pfam07653    pfam14604   
Domain families : Smart (EMBL)BAR (SM00721)  RhoGEF (SM00325)  SH3 (SM00326)  
Conserved Domain (NCBI)DNMBP
DMDM Disease mutations23268
Blocks (Seattle)DNMBP
PDB (RSDB)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB Europe1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB (PDBSum)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
PDB (IMB)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
Structural Biology KnowledgeBase1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
SCOP (Structural Classification of Proteins)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
CATH (Classification of proteins structures)1UG1    1UHC    4CC2    4CC3    4CC4    4CC7    4GLM   
SuperfamilyQ6XZF7
Human Protein Atlas [tissue]ENSG00000107554-DNMBP [tissue]
Peptide AtlasQ6XZF7
HPRD10918
IPIIPI00174025   IPI00480148   IPI00873922   IPI01014969   IPI01011375   IPI00514447   
Protein Interaction databases
DIP (DOE-UCLA)Q6XZF7
IntAct (EBI)Q6XZF7
FunCoupENSG00000107554
BioGRIDDNMBP
STRING (EMBL)DNMBP
ZODIACDNMBP
Ontologies - Pathways
QuickGOQ6XZF7
Ontology : AmiGORho guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  protein binding  Golgi apparatus  Golgi stack  cytoskeleton  cell-cell junction  aging  regulation of cell shape  intracellular signal transduction  synapse  presynapse  
Ontology : EGO-EBIRho guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  protein binding  Golgi apparatus  Golgi stack  cytoskeleton  cell-cell junction  aging  regulation of cell shape  intracellular signal transduction  synapse  presynapse  
NDEx NetworkDNMBP
Atlas of Cancer Signalling NetworkDNMBP
Wikipedia pathwaysDNMBP
Orthology - Evolution
OrthoDB23268
GeneTree (enSembl)ENSG00000107554
Phylogenetic Trees/Animal Genes : TreeFamDNMBP
HOGENOMQ6XZF7
Homologs : HomoloGeneDNMBP
Homology/Alignments : Family Browser (UCSC)DNMBP
Gene fusions - Rearrangements
Fusion : MitelmanDNMBP/TPTE2 [10q24.2/13q12.11]  
Fusion PortalDNMBP 10q24.2 TPTE2 13q12.11 LUSC
Fusion : QuiverDNMBP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNMBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNMBP
dbVarDNMBP
ClinVarDNMBP
1000_GenomesDNMBP 
Exome Variant ServerDNMBP
GNOMAD BrowserENSG00000107554
Varsome BrowserDNMBP
Genetic variants : HAPMAP23268
Genomic Variants (DGV)DNMBP [DGVbeta]
DECIPHERDNMBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNMBP 
Mutations
ICGC Data PortalDNMBP 
TCGA Data PortalDNMBP 
Broad Tumor PortalDNMBP
OASIS PortalDNMBP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDNMBP  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDNMBP
Mutations and Diseases : HGMDDNMBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DNMBP
DgiDB (Drug Gene Interaction Database)DNMBP
DoCM (Curated mutations)DNMBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNMBP (select a term)
intoGenDNMBP
Cancer3DDNMBP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611282    618415   
Orphanet
DisGeNETDNMBP
MedgenDNMBP
Genetic Testing Registry DNMBP
NextProtQ6XZF7 [Medical]
TSGene23268
GENETestsDNMBP
Target ValidationDNMBP
Huge Navigator DNMBP [HugePedia]
snp3D : Map Gene to Disease23268
BioCentury BCIQDNMBP
ClinGenDNMBP
Clinical trials, drugs, therapy
Protein Interactions : CTD23268
Pharm GKB GenePA134950706
Clinical trialDNMBP
Miscellaneous
canSAR (ICR)DNMBP (select the gene name)
HarmonizomeDNMBP
DataMed IndexDNMBP
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNMBP
EVEXDNMBP
GoPubMedDNMBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:11:03 CEST 2020
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