DNMT3A (DNA (cytosine-5-)-methyltransferase 3 alpha)

Identity

Other names	DNMT3A2
	M.HsaIIIA
HGNC	DNMT3A
Location	2p23
Location_base_pair	Starts at 25309349 and ends at 25418278 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DNMT3A   2978
Entrez_Gene	DNMT3A  1788  DNA (cytosine-5-)-methyltransferase 3 alpha
	Cards
GeneCards	DNMT3A
Ensembl	DNMT3A [Search_View]   ENSG00000119772 [Gene_View]
Genatlas	DNMT3A
GeneLynx	DNMT3A
eGenome	DNMT3A
euGene	1788
	Genomic and cartography
GoldenPath	DNMT3A  -  2p23   chr2:25309349-25418278 -  2p23.3   [Description]    (hg18-March_2006)
Ensembl	DNMT3A - 2p23.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DNMT3A
	Gene and transcription
Genbank	AB208833 [ ENTREZ ]
Genbank	AF067972 [ ENTREZ ]
Genbank	AF331856 [ ENTREZ ]
Genbank	AF480163 [ ENTREZ ]
Genbank	AK025230 [ ENTREZ ]
RefSeq	NM_022552 [ SRS ]    NM_022552 [ ENTREZ ]
RefSeq	NM_153759 [ SRS ]    NM_153759 [ ENTREZ ]
RefSeq	NM_175629 [ SRS ]    NM_175629 [ ENTREZ ]
RefSeq	NM_175630 [ SRS ]    NM_175630 [ ENTREZ ]
RefSeq	AC_000045 [ SRS ]    AC_000045 [ ENTREZ ]
RefSeq	AC_000134 [ SRS ]    AC_000134 [ ENTREZ ]
RefSeq	NC_000002 [ SRS ]    NC_000002 [ ENTREZ ]
RefSeq	NT_022184 [ SRS ]    NT_022184 [ ENTREZ ]
RefSeq	NW_001838768 [ SRS ]    NW_001838768 [ ENTREZ ]
RefSeq	NW_927719 [ SRS ]    NW_927719 [ ENTREZ ]
AceView	DNMT3A AceView - NCBI
Unigene	Hs.515840 [ SRS ]    Hs.515840 [ NCBI ]     HS515840 [ spliceNest ]
Fast-db	2301 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q59HC6 [ SRS]    Q59HC6 [ EXPASY ]     Q59HC6 [ INTERPRO ]     Q59HC6 [ UNIPROT ]
Prosite	PS00094 C5_MTASE_1 [ SRS ]    PS00094 C5_MTASE_1 [ Expasy ]
Prosite	PS50812 PWWP [ SRS ]    PS50812 PWWP [ Expasy ]
Interpro	IPR001525 C5_DNA_meth [ SRS ]    IPR001525 C5_DNA_meth [ EBI ]
Interpro	IPR000313 PWWP [ SRS ]    IPR000313 PWWP [ EBI ]
CluSTr	Q59HC6
Pfam	PF00145 DNA_methylase [ SRS ]    PF00145 DNA_methylase [ Sanger ]    pfam00145 [ NCBI-CDD ]
Pfam	PF00855 PWWP [ SRS ]    PF00855 PWWP [ Sanger ]    pfam00855 [ NCBI-CDD ]
Smart	SM00293 PWWP [EMBL]
Blocks	Q59HC6
HPRD	04141
	Protein Interaction databases
DIP	Q59HC6
IntAct	Q59HC6
	Polymorphism : SNP, mutations, diseases
OMIM	602769    [ map ]
GENECLINICS	602769
SNP	DNMT3A [dbSNP-NCBI]
SNP	NM_022552 [SNP-NCI]
SNP	NM_153759 [SNP-NCI]
SNP	NM_175629 [SNP-NCI]
SNP	NM_175630 [SNP-NCI]
SNP	DNMT3A [GeneSNPs - Utah]  DNMT3A] [HGBASE - SRS]
HAPMAP	DNMT3A [HAPMAP]
COSMIC	DNMT3A [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	DNMT3A
	General knowledge
Family Browser	DNMT3A [UCSC Family Browser]
SOURCE	NM_022552
SOURCE	NM_153759
SOURCE	NM_175629
SOURCE	NM_175630
SMD	Hs.515840
SAGE	Hs.515840
GO	euchromatin [Amigo]  euchromatin
GO	DNA binding [Amigo]  DNA binding
GO	DNA binding [Amigo]  DNA binding
GO	DNA (cytosine-5-)-methyltransferase activity [Amigo]  DNA (cytosine-5-)-methyltransferase activity
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	DNA methylation [Amigo]  DNA methylation
GO	DNA methylation [Amigo]  DNA methylation
GO	methyltransferase activity [Amigo]  methyltransferase activity
GO	zinc ion binding [Amigo]  zinc ion binding
GO	nuclear matrix [Amigo]  nuclear matrix
GO	transferase activity [Amigo]  transferase activity
GO	metal ion binding [Amigo]  metal ion binding
KEGG	Methionine metabolism
PubGene	DNMT3A
TreeFam	DNMT3A
CTD	1788 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DNMT3A Related clones (RZPD - Berlin)
	PubMed
PubMed	40 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:10:48 2008