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DNPH1 (2'-deoxynucleoside 5'-phosphate N-hydrolase 1)

Identity

Alias_namesC6orf108
chromosome 6 open reading frame 108
Alias_symbol (synonym)rcl
dJ330M21.3
Other aliasRCL
HGNC (Hugo) DNPH1
LocusID (NCBI) 10591
Atlas_Id 56226
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43225629 and ends at 43229473 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DNPH1   21218
Cards
Entrez_Gene (NCBI)DNPH1  10591  2'-deoxynucleoside 5'-phosphate N-hydrolase 1
AliasesC6orf108; RCL; dJ330M21.3
GeneCards (Weizmann)DNPH1
Ensembl hg19 (Hinxton)ENSG00000112667 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112667 [Gene_View]  ENSG00000112667 [Sequence]  chr6:43225629-43229473 [Contig_View]  DNPH1 [Vega]
ICGC DataPortalENSG00000112667
TCGA cBioPortalDNPH1
AceView (NCBI)DNPH1
Genatlas (Paris)DNPH1
WikiGenes10591
SOURCE (Princeton)DNPH1
Genetics Home Reference (NIH)DNPH1
Genomic and cartography
GoldenPath hg38 (UCSC)DNPH1  -     chr6:43225629-43229473 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DNPH1  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblDNPH1 - 6p21.1 [CytoView hg19]  DNPH1 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIDNPH1 [Mapview hg19]  DNPH1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF040105 BC011683 BM747628 BQ052226 EU585603
RefSeq transcript (Entrez)NM_006443 NM_199184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DNPH1
Cluster EST : UnigeneHs.109752 [ NCBI ]
CGAP (NCI)Hs.109752
Alternative Splicing GalleryENSG00000112667
Gene ExpressionDNPH1 [ NCBI-GEO ]   DNPH1 [ EBI - ARRAY_EXPRESS ]   DNPH1 [ SEEK ]   DNPH1 [ MEM ]
Gene Expression Viewer (FireBrowse)DNPH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10591
GTEX Portal (Tissue expression)DNPH1
Human Protein AtlasENSG00000112667-DNPH1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43598   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43598  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43598
Splice isoforms : SwissVarO43598
PhosPhoSitePlusO43598
Domains : Interpro (EBI)DNPH1    Nucleoside_deoxyribTrfase   
Domain families : Pfam (Sanger)Nuc_deoxyrib_tr (PF05014)   
Domain families : Pfam (NCBI)pfam05014   
Conserved Domain (NCBI)DNPH1
DMDM Disease mutations10591
Blocks (Seattle)DNPH1
PDB (SRS)4P5E   
PDB (PDBSum)4P5E   
PDB (IMB)4P5E   
PDB (RSDB)4P5E   
Structural Biology KnowledgeBase4P5E   
SCOP (Structural Classification of Proteins)4P5E   
CATH (Classification of proteins structures)4P5E   
SuperfamilyO43598
Human Protein Atlas [tissue]ENSG00000112667-DNPH1 [tissue]
Peptide AtlasO43598
HPRD06707
IPIIPI00007926   IPI00395835   IPI00967902   
Protein Interaction databases
DIP (DOE-UCLA)O43598
IntAct (EBI)O43598
FunCoupENSG00000112667
BioGRIDDNPH1
STRING (EMBL)DNPH1
ZODIACDNPH1
Ontologies - Pathways
QuickGOO43598
Ontology : AmiGOprotein binding  nucleus  cytosol  purine nucleotide catabolic process  cell proliferation  deoxyribonucleoside monophosphate catabolic process  deoxyribonucleoside monophosphate catabolic process  positive regulation of cell growth  epithelial cell differentiation  identical protein binding  protein homodimerization activity  nucleoside deoxyribosyltransferase activity  extracellular exosome  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  
Ontology : EGO-EBIprotein binding  nucleus  cytosol  purine nucleotide catabolic process  cell proliferation  deoxyribonucleoside monophosphate catabolic process  deoxyribonucleoside monophosphate catabolic process  positive regulation of cell growth  epithelial cell differentiation  identical protein binding  protein homodimerization activity  nucleoside deoxyribosyltransferase activity  extracellular exosome  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  deoxyribonucleoside 5'-monophosphate N-glycosidase activity  
NDEx NetworkDNPH1
Atlas of Cancer Signalling NetworkDNPH1
Wikipedia pathwaysDNPH1
Orthology - Evolution
OrthoDB10591
GeneTree (enSembl)ENSG00000112667
Phylogenetic Trees/Animal Genes : TreeFamDNPH1
HOVERGENO43598
HOGENOMO43598
Homologs : HomoloGeneDNPH1
Homology/Alignments : Family Browser (UCSC)DNPH1
Gene fusions - Rearrangements
Fusion : QuiverDNPH1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDNPH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DNPH1
dbVarDNPH1
ClinVarDNPH1
1000_GenomesDNPH1 
Exome Variant ServerDNPH1
ExAC (Exome Aggregation Consortium)ENSG00000112667
GNOMAD BrowserENSG00000112667
Genetic variants : HAPMAP10591
Genomic Variants (DGV)DNPH1 [DGVbeta]
DECIPHERDNPH1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDNPH1 
Mutations
ICGC Data PortalDNPH1 
TCGA Data PortalDNPH1 
Broad Tumor PortalDNPH1
OASIS PortalDNPH1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDDNPH1
BioMutasearch DNPH1
DgiDB (Drug Gene Interaction Database)DNPH1
DoCM (Curated mutations)DNPH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DNPH1 (select a term)
intoGenDNPH1
Cancer3DDNPH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETDNPH1
MedgenDNPH1
Genetic Testing Registry DNPH1
NextProtO43598 [Medical]
TSGene10591
GENETestsDNPH1
Target ValidationDNPH1
Huge Navigator DNPH1 [HugePedia]
snp3D : Map Gene to Disease10591
BioCentury BCIQDNPH1
ClinGenDNPH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10591
Chemical/Pharm GKB GenePA134918815
Clinical trialDNPH1
Miscellaneous
canSAR (ICR)DNPH1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDNPH1
EVEXDNPH1
GoPubMedDNPH1
iHOPDNPH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:23:05 CEST 2018

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