Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DOC2B (double C2 domain beta)

Identity

Alias_namesDOC2BL
double C2-like domains, beta-like
double C2-like domains, beta
Other alias
HGNC (Hugo) DOC2B
LocusID (NCBI) 8447
Atlas_Id 54033
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 6011 and ends at 31421 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOC2B   2986
Cards
Entrez_Gene (NCBI)DOC2B  8447  double C2 domain beta
AliasesDOC2BL
GeneCards (Weizmann)DOC2B
Ensembl hg19 (Hinxton)ENSG00000272636 [Gene_View]  chr17:6011-31421 [Contig_View]  DOC2B [Vega]
Ensembl hg38 (Hinxton)ENSG00000272636 [Gene_View]  chr17:6011-31421 [Contig_View]  DOC2B [Vega]
ICGC DataPortalENSG00000272636
TCGA cBioPortalDOC2B
AceView (NCBI)DOC2B
Genatlas (Paris)DOC2B
WikiGenes8447
SOURCE (Princeton)DOC2B
Genetics Home Reference (NIH)DOC2B
Genomic and cartography
GoldenPath hg19 (UCSC)DOC2B  -     chr17:6011-31421 -  17p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DOC2B  -     17p13.3   [Description]    (hg38-Dec_2013)
EnsemblDOC2B - 17p13.3 [CytoView hg19]  DOC2B - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBIDOC2B [Mapview hg19]  DOC2B [Mapview hg38]
OMIM604568   
Gene and transcription
Genbank (Entrez)AI478508 BC152720 BC153024 BM713588 D70830
RefSeq transcript (Entrez)NM_003585
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_021143 NT_024972 NW_003315952 NW_004929404
Consensus coding sequences : CCDS (NCBI)DOC2B
Cluster EST : UnigeneHs.551705 [ NCBI ]
CGAP (NCI)Hs.551705
Alternative Splicing GalleryENSG00000272636
Gene ExpressionDOC2B [ NCBI-GEO ]   DOC2B [ EBI - ARRAY_EXPRESS ]   DOC2B [ SEEK ]   DOC2B [ MEM ]
Gene Expression Viewer (FireBrowse)DOC2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8447
GTEX Portal (Tissue expression)DOC2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14184   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14184  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14184
Splice isoforms : SwissVarQ14184
PhosPhoSitePlusQ14184
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (EBI)C2_dom    Doc2    Doc2b    Synaptotagmin   
Domain families : Pfam (Sanger)C2 (PF00168)   
Domain families : Pfam (NCBI)pfam00168   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)DOC2B
DMDM Disease mutations8447
Blocks (Seattle)DOC2B
SuperfamilyQ14184
Human Protein AtlasENSG00000272636
Peptide AtlasQ14184
HPRD05196
IPIIPI00020684   
Protein Interaction databases
DIP (DOE-UCLA)Q14184
IntAct (EBI)Q14184
FunCoupENSG00000272636
BioGRIDDOC2B
STRING (EMBL)DOC2B
ZODIACDOC2B
Ontologies - Pathways
QuickGOQ14184
Ontology : AmiGOcalcium ion binding  calcium-dependent phospholipid binding  calcium-dependent phospholipid binding  cytoplasm  plasma membrane  plasma membrane  vesicle fusion  protein localization  regulation of calcium ion-dependent exocytosis  syntaxin binding  clathrin binding  SNARE complex  positive regulation of vesicle fusion  positive regulation of insulin secretion  positive regulation of calcium ion-dependent exocytosis  calcium ion-regulated exocytosis of neurotransmitter  calcium ion-regulated exocytosis of neurotransmitter  presynapse  presynapse  presynapse  
Ontology : EGO-EBIcalcium ion binding  calcium-dependent phospholipid binding  calcium-dependent phospholipid binding  cytoplasm  plasma membrane  plasma membrane  vesicle fusion  protein localization  regulation of calcium ion-dependent exocytosis  syntaxin binding  clathrin binding  SNARE complex  positive regulation of vesicle fusion  positive regulation of insulin secretion  positive regulation of calcium ion-dependent exocytosis  calcium ion-regulated exocytosis of neurotransmitter  calcium ion-regulated exocytosis of neurotransmitter  presynapse  presynapse  presynapse  
NDEx NetworkDOC2B
Atlas of Cancer Signalling NetworkDOC2B
Wikipedia pathwaysDOC2B
Orthology - Evolution
OrthoDB8447
GeneTree (enSembl)ENSG00000272636
Phylogenetic Trees/Animal Genes : TreeFamDOC2B
HOVERGENQ14184
HOGENOMQ14184
Homologs : HomoloGeneDOC2B
Homology/Alignments : Family Browser (UCSC)DOC2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOC2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOC2B
dbVarDOC2B
ClinVarDOC2B
1000_GenomesDOC2B 
Exome Variant ServerDOC2B
ExAC (Exome Aggregation Consortium)DOC2B (select the gene name)
Genetic variants : HAPMAP8447
Genomic Variants (DGV)DOC2B [DGVbeta]
DECIPHER (Syndromes)17:6011-31421  ENSG00000272636
CONAN: Copy Number AnalysisDOC2B 
Mutations
ICGC Data PortalDOC2B 
TCGA Data PortalDOC2B 
Broad Tumor PortalDOC2B
OASIS PortalDOC2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOC2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOC2B
BioMutasearch DOC2B
DgiDB (Drug Gene Interaction Database)DOC2B
DoCM (Curated mutations)DOC2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOC2B (select a term)
intoGenDOC2B
Cancer3DDOC2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604568   
Orphanet
MedgenDOC2B
Genetic Testing Registry DOC2B
NextProtQ14184 [Medical]
TSGene8447
GENETestsDOC2B
Huge Navigator DOC2B [HugePedia]
snp3D : Map Gene to Disease8447
BioCentury BCIQDOC2B
ClinGenDOC2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8447
Chemical/Pharm GKB GenePA27452
Clinical trialDOC2B
Miscellaneous
canSAR (ICR)DOC2B (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOC2B
EVEXDOC2B
GoPubMedDOC2B
iHOPDOC2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:03:41 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.