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DOCK11 (dedicator of cytokinesis 11)

Identity

Alias_symbol (synonym)FLJ32122
FLJ43653
ZIZ2
ACG
Other aliasbB128O4.1
HGNC (Hugo) DOCK11
LocusID (NCBI) 139818
Atlas_Id 62589
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 118495909 and ends at 118686160 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DOCK11 (Xq24) / DOCK11 (Xq24)DOCK11 (Xq24) / KMT2A (11q23.3)IL13RA1 (Xq24) / DOCK11 (Xq24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOCK11   23483
Cards
Entrez_Gene (NCBI)DOCK11  139818  dedicator of cytokinesis 11
AliasesACG; ZIZ2; bB128O4.1
GeneCards (Weizmann)DOCK11
Ensembl hg19 (Hinxton)ENSG00000147251 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147251 [Gene_View]  chrX:118495909-118686160 [Contig_View]  DOCK11 [Vega]
ICGC DataPortalENSG00000147251
TCGA cBioPortalDOCK11
AceView (NCBI)DOCK11
Genatlas (Paris)DOCK11
WikiGenes139818
SOURCE (Princeton)DOCK11
Genetics Home Reference (NIH)DOCK11
Genomic and cartography
GoldenPath hg38 (UCSC)DOCK11  -     chrX:118495909-118686160 +  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DOCK11  -     Xq24   [Description]    (hg19-Feb_2009)
EnsemblDOCK11 - Xq24 [CytoView hg19]  DOCK11 - Xq24 [CytoView hg38]
Mapping of homologs : NCBIDOCK11 [Mapview hg19]  DOCK11 [Mapview hg38]
OMIM300681   
Gene and transcription
Genbank (Entrez)AA490413 AI361832 AI936555 AK054649 AK056684
RefSeq transcript (Entrez)NM_144658
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DOCK11
Cluster EST : UnigeneHs.368203 [ NCBI ]
CGAP (NCI)Hs.368203
Alternative Splicing GalleryENSG00000147251
Gene ExpressionDOCK11 [ NCBI-GEO ]   DOCK11 [ EBI - ARRAY_EXPRESS ]   DOCK11 [ SEEK ]   DOCK11 [ MEM ]
Gene Expression Viewer (FireBrowse)DOCK11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)139818
GTEX Portal (Tissue expression)DOCK11
Human Protein AtlasENSG00000147251-DOCK11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JSL3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JSL3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JSL3
Splice isoforms : SwissVarQ5JSL3
PhosPhoSitePlusQ5JSL3
Domaine pattern : Prosite (Expaxy)DHR_1 (PS51650)    DHR_2 (PS51651)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)ARM-type_fold    DHR-1_domain    DHR-2    DOCK    DOCK_C    DOCK_C/D_N    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)DHR-2 (PF06920)    DOCK-C2 (PF14429)    DUF3398 (PF11878)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam06920    pfam14429    pfam11878    pfam00169   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)DOCK11
DMDM Disease mutations139818
Blocks (Seattle)DOCK11
SuperfamilyQ5JSL3
Human Protein Atlas [tissue]ENSG00000147251-DOCK11 [tissue]
Peptide AtlasQ5JSL3
HPRD06492
IPIIPI00748916   IPI00411452   
Protein Interaction databases
DIP (DOE-UCLA)Q5JSL3
IntAct (EBI)Q5JSL3
FunCoupENSG00000147251
BioGRIDDOCK11
STRING (EMBL)DOCK11
ZODIACDOCK11
Ontologies - Pathways
QuickGOQ5JSL3
Ontology : AmiGOB cell homeostasis  marginal zone B cell differentiation  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  protein binding  cytosol  small GTPase mediated signal transduction  blood coagulation  Rho GTPase binding  positive regulation of GTPase activity  positive regulation of filopodium assembly  
Ontology : EGO-EBIB cell homeostasis  marginal zone B cell differentiation  guanyl-nucleotide exchange factor activity  Rho guanyl-nucleotide exchange factor activity  protein binding  cytosol  small GTPase mediated signal transduction  blood coagulation  Rho GTPase binding  positive regulation of GTPase activity  positive regulation of filopodium assembly  
NDEx NetworkDOCK11
Atlas of Cancer Signalling NetworkDOCK11
Wikipedia pathwaysDOCK11
Orthology - Evolution
OrthoDB139818
GeneTree (enSembl)ENSG00000147251
Phylogenetic Trees/Animal Genes : TreeFamDOCK11
HOVERGENQ5JSL3
HOGENOMQ5JSL3
Homologs : HomoloGeneDOCK11
Homology/Alignments : Family Browser (UCSC)DOCK11
Gene fusions - Rearrangements
Tumor Fusion PortalDOCK11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOCK11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOCK11
dbVarDOCK11
ClinVarDOCK11
1000_GenomesDOCK11 
Exome Variant ServerDOCK11
ExAC (Exome Aggregation Consortium)ENSG00000147251
GNOMAD BrowserENSG00000147251
Genetic variants : HAPMAP139818
Genomic Variants (DGV)DOCK11 [DGVbeta]
DECIPHERDOCK11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDOCK11 
Mutations
ICGC Data PortalDOCK11 
TCGA Data PortalDOCK11 
Broad Tumor PortalDOCK11
OASIS PortalDOCK11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOCK11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOCK11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOCK11
DgiDB (Drug Gene Interaction Database)DOCK11
DoCM (Curated mutations)DOCK11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOCK11 (select a term)
intoGenDOCK11
Cancer3DDOCK11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300681   
Orphanet
DisGeNETDOCK11
MedgenDOCK11
Genetic Testing Registry DOCK11
NextProtQ5JSL3 [Medical]
TSGene139818
GENETestsDOCK11
Target ValidationDOCK11
Huge Navigator DOCK11 [HugePedia]
snp3D : Map Gene to Disease139818
BioCentury BCIQDOCK11
ClinGenDOCK11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD139818
Chemical/Pharm GKB GenePA128394757
Clinical trialDOCK11
Miscellaneous
canSAR (ICR)DOCK11 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOCK11
EVEXDOCK11
GoPubMedDOCK11
iHOPDOCK11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:59:26 CET 2017

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