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DOCK5 (dedicator of cytokinesis 5)

Identity

Alias_symbol (synonym)FLJ21034
Other alias-
HGNC (Hugo) DOCK5
LocusID (NCBI) 80005
Atlas_Id 54260
Location 8p21.2  [Link to chromosome band 8p21]
Location_base_pair Starts at 25042287 and ends at 25270619 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DOCK5 (8p21.2) / DOCK5 (8p21.2)ITPR1 (3p26.1) / DOCK5 (8p21.2)STARD3 (17q12) / DOCK5 (8p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOCK5   23476
Cards
Entrez_Gene (NCBI)DOCK5  80005  dedicator of cytokinesis 5
Aliases
GeneCards (Weizmann)DOCK5
Ensembl hg19 (Hinxton)ENSG00000147459 [Gene_View]  chr8:25042287-25270619 [Contig_View]  DOCK5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000147459 [Gene_View]  chr8:25042287-25270619 [Contig_View]  DOCK5 [Vega]
ICGC DataPortalENSG00000147459
TCGA cBioPortalDOCK5
AceView (NCBI)DOCK5
Genatlas (Paris)DOCK5
WikiGenes80005
SOURCE (Princeton)DOCK5
Genetics Home Reference (NIH)DOCK5
Genomic and cartography
GoldenPath hg19 (UCSC)DOCK5  -     chr8:25042287-25270619 +  8p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DOCK5  -     8p21.2   [Description]    (hg38-Dec_2013)
EnsemblDOCK5 - 8p21.2 [CytoView hg19]  DOCK5 - 8p21.2 [CytoView hg38]
Mapping of homologs : NCBIDOCK5 [Mapview hg19]  DOCK5 [Mapview hg38]
OMIM616904   
Gene and transcription
Genbank (Entrez)AK022242 AK024687 AK026663 AK123607 AK126249
RefSeq transcript (Entrez)NM_001322810 NM_024940
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)DOCK5
Cluster EST : UnigeneHs.195403 [ NCBI ]
CGAP (NCI)Hs.195403
Alternative Splicing GalleryENSG00000147459
Gene ExpressionDOCK5 [ NCBI-GEO ]   DOCK5 [ EBI - ARRAY_EXPRESS ]   DOCK5 [ SEEK ]   DOCK5 [ MEM ]
Gene Expression Viewer (FireBrowse)DOCK5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80005
GTEX Portal (Tissue expression)DOCK5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H7D0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H7D0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H7D0
Splice isoforms : SwissVarQ9H7D0
PhosPhoSitePlusQ9H7D0
Domaine pattern : Prosite (Expaxy)DHR_1 (PS51650)    DHR_2 (PS51651)    SH3 (PS50002)   
Domains : Interpro (EBI)ARM-type_fold    DHR-1_domain    DHR-2    DOCK    DOCK_C    DOCK_N    SH3_domain   
Domain families : Pfam (Sanger)DHR-2 (PF06920)    DOCK-C2 (PF14429)    DOCK_N (PF16172)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam06920    pfam14429    pfam16172    pfam00018   
Domain families : Smart (EMBL)SH3 (SM00326)  
Conserved Domain (NCBI)DOCK5
DMDM Disease mutations80005
Blocks (Seattle)DOCK5
SuperfamilyQ9H7D0
Human Protein AtlasENSG00000147459
Peptide AtlasQ9H7D0
HPRD09925
IPIIPI00746684   IPI00816677   IPI00917443   IPI00791507   IPI01014859   
Protein Interaction databases
DIP (DOE-UCLA)Q9H7D0
IntAct (EBI)Q9H7D0
FunCoupENSG00000147459
BioGRIDDOCK5
STRING (EMBL)DOCK5
ZODIACDOCK5
Ontologies - Pathways
QuickGOQ9H7D0
Ontology : AmiGOguanyl-nucleotide exchange factor activity  cytoplasm  cytoplasm  small GTPase mediated signal transduction  positive regulation of GTPase activity  negative regulation of vascular smooth muscle contraction  positive regulation of vascular associated smooth muscle cell migration  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  cytoplasm  cytoplasm  small GTPase mediated signal transduction  positive regulation of GTPase activity  negative regulation of vascular smooth muscle contraction  positive regulation of vascular associated smooth muscle cell migration  
NDEx NetworkDOCK5
Atlas of Cancer Signalling NetworkDOCK5
Wikipedia pathwaysDOCK5
Orthology - Evolution
OrthoDB80005
GeneTree (enSembl)ENSG00000147459
Phylogenetic Trees/Animal Genes : TreeFamDOCK5
HOVERGENQ9H7D0
HOGENOMQ9H7D0
Homologs : HomoloGeneDOCK5
Homology/Alignments : Family Browser (UCSC)DOCK5
Gene fusions - Rearrangements
Fusion : MitelmanSTARD3/DOCK5 [17q12/8p21.2]  [t(8;17)(p21;q12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOCK5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOCK5
dbVarDOCK5
ClinVarDOCK5
1000_GenomesDOCK5 
Exome Variant ServerDOCK5
ExAC (Exome Aggregation Consortium)DOCK5 (select the gene name)
Genetic variants : HAPMAP80005
Genomic Variants (DGV)DOCK5 [DGVbeta]
DECIPHER (Syndromes)8:25042287-25270619  ENSG00000147459
CONAN: Copy Number AnalysisDOCK5 
Mutations
ICGC Data PortalDOCK5 
TCGA Data PortalDOCK5 
Broad Tumor PortalDOCK5
OASIS PortalDOCK5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOCK5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOCK5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOCK5
DgiDB (Drug Gene Interaction Database)DOCK5
DoCM (Curated mutations)DOCK5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOCK5 (select a term)
intoGenDOCK5
Cancer3DDOCK5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616904   
Orphanet
MedgenDOCK5
Genetic Testing Registry DOCK5
NextProtQ9H7D0 [Medical]
TSGene80005
GENETestsDOCK5
Huge Navigator DOCK5 [HugePedia]
snp3D : Map Gene to Disease80005
BioCentury BCIQDOCK5
ClinGenDOCK5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80005
Chemical/Pharm GKB GenePA134932307
Clinical trialDOCK5
Miscellaneous
canSAR (ICR)DOCK5 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOCK5
EVEXDOCK5
GoPubMedDOCK5
iHOPDOCK5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:43 CET 2017

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