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DOCK7 (dedicator of cytokinesis 7)

Identity

Alias_symbol (synonym)KIAA1771
ZIR2
Other aliasEIEE23
HGNC (Hugo) DOCK7
LocusID (NCBI) 85440
Atlas_Id 62591
Location 1p31.3  [Link to chromosome band 1p31]
Location_base_pair Starts at 62454726 and ends at 62688368 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DOCK7 (1p31.3) / IQCG (3q29)DOCK7 (1p31.3) / PATJ (1p31.3)DOCK7 (1p31.3) / PPP1R12B (1q32.1)
IQCG (3q29) / DOCK7 (1p31.3)NIPSNAP1 (22q12.2) / DOCK7 (1p31.3)DOCK7 PPP1R12B
DOCK7 INADL

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOCK7   19190
Cards
Entrez_Gene (NCBI)DOCK7  85440  dedicator of cytokinesis 7
AliasesEIEE23; ZIR2
GeneCards (Weizmann)DOCK7
Ensembl hg19 (Hinxton)ENSG00000116641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116641 [Gene_View]  chr1:62454726-62688368 [Contig_View]  DOCK7 [Vega]
ICGC DataPortalENSG00000116641
TCGA cBioPortalDOCK7
AceView (NCBI)DOCK7
Genatlas (Paris)DOCK7
WikiGenes85440
SOURCE (Princeton)DOCK7
Genetics Home Reference (NIH)DOCK7
Genomic and cartography
GoldenPath hg38 (UCSC)DOCK7  -     chr1:62454726-62688368 -  1p31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DOCK7  -     1p31.3   [Description]    (hg19-Feb_2009)
EnsemblDOCK7 - 1p31.3 [CytoView hg19]  DOCK7 - 1p31.3 [CytoView hg38]
Mapping of homologs : NCBIDOCK7 [Mapview hg19]  DOCK7 [Mapview hg38]
OMIM615730   615859   
Gene and transcription
Genbank (Entrez)AB051558 AK022097 AK055296 AK055401 AK055493
RefSeq transcript (Entrez)NM_001271999 NM_001272000 NM_001272001 NM_001272002 NM_001330614 NM_033407
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DOCK7
Cluster EST : UnigeneHs.744927 [ NCBI ]
CGAP (NCI)Hs.744927
Alternative Splicing GalleryENSG00000116641
Gene ExpressionDOCK7 [ NCBI-GEO ]   DOCK7 [ EBI - ARRAY_EXPRESS ]   DOCK7 [ SEEK ]   DOCK7 [ MEM ]
Gene Expression Viewer (FireBrowse)DOCK7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85440
GTEX Portal (Tissue expression)DOCK7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96N67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96N67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96N67
Splice isoforms : SwissVarQ96N67
PhosPhoSitePlusQ96N67
Domaine pattern : Prosite (Expaxy)DHR_1 (PS51650)    DHR_2 (PS51651)   
Domains : Interpro (EBI)DHR-1_domain    DHR-2    DOCK    DOCK_C    DOCK_C/D_N   
Domain families : Pfam (Sanger)DHR-2 (PF06920)    DOCK-C2 (PF14429)    DUF3398 (PF11878)   
Domain families : Pfam (NCBI)pfam06920    pfam14429    pfam11878   
Conserved Domain (NCBI)DOCK7
DMDM Disease mutations85440
Blocks (Seattle)DOCK7
SuperfamilyQ96N67
Human Protein AtlasENSG00000116641
Peptide AtlasQ96N67
HPRD16833
IPIIPI00513791   IPI00183572   IPI00807434   IPI00816106   IPI00815886   IPI00815633   IPI01008893   IPI00043678   
Protein Interaction databases
DIP (DOE-UCLA)Q96N67
IntAct (EBI)Q96N67
FunCoupENSG00000116641
BioGRIDDOCK7
STRING (EMBL)DOCK7
ZODIACDOCK7
Ontologies - Pathways
QuickGOQ96N67
Ontology : AmiGOmicrotubule cytoskeleton organization  guanyl-nucleotide exchange factor activity  focal adhesion  small GTPase mediated signal transduction  axonogenesis  COP9 signalosome  interkinetic nuclear migration  axon  growth cone  neuron projection development  positive regulation of peptidyl-serine phosphorylation  neuron projection  basal part of cell  establishment of neuroblast polarity  Rac GTPase binding  regulation of neurogenesis  activation of GTPase activity  positive regulation of vascular associated smooth muscle cell migration  
Ontology : EGO-EBImicrotubule cytoskeleton organization  guanyl-nucleotide exchange factor activity  focal adhesion  small GTPase mediated signal transduction  axonogenesis  COP9 signalosome  interkinetic nuclear migration  axon  growth cone  neuron projection development  positive regulation of peptidyl-serine phosphorylation  neuron projection  basal part of cell  establishment of neuroblast polarity  Rac GTPase binding  regulation of neurogenesis  activation of GTPase activity  positive regulation of vascular associated smooth muscle cell migration  
NDEx NetworkDOCK7
Atlas of Cancer Signalling NetworkDOCK7
Wikipedia pathwaysDOCK7
Orthology - Evolution
OrthoDB85440
GeneTree (enSembl)ENSG00000116641
Phylogenetic Trees/Animal Genes : TreeFamDOCK7
HOVERGENQ96N67
HOGENOMQ96N67
Homologs : HomoloGeneDOCK7
Homology/Alignments : Family Browser (UCSC)DOCK7
Gene fusions - Rearrangements
Fusion: TCGADOCK7 PPP1R12B
Fusion: TCGADOCK7 INADL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOCK7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOCK7
dbVarDOCK7
ClinVarDOCK7
1000_GenomesDOCK7 
Exome Variant ServerDOCK7
ExAC (Exome Aggregation Consortium)DOCK7 (select the gene name)
Genetic variants : HAPMAP85440
Genomic Variants (DGV)DOCK7 [DGVbeta]
DECIPHERDOCK7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDOCK7 
Mutations
ICGC Data PortalDOCK7 
TCGA Data PortalDOCK7 
Broad Tumor PortalDOCK7
OASIS PortalDOCK7 [ Somatic mutations - Cop} num`eb]
Somatic Mutations in Cancer : COSMICDOCK7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOCK7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOCK7
DgiDB (Drug Gene Interaction Database)DOCK7
DoCM (Curated mutations)DOCK7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOCK7 (select a term)
intoGenDOCK7
Cancer3DDOCK7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615730    615859   
Orphanet23037   
MedgenDOCK7
Genetic Testing Registry DOCK7
NextProtQ96N67 [Medical]
TSGene85440
GENETestsDOCK7
Target ValidationDOCK7
Huge Navigator DOCK7 [HugePedia]
snp3D : Map Gene to Disease85440
BioCentury BCIQDOCK7
ClinGenDOCK7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85440
Chemical/Pharm GKB GenePA134872825
Clinical trialDOCK7
Miscellaneous
canSAR (ICR)DOCK7 (select the gene name)
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOCK7
EVEXDOCK7
GoPubMedDOCK7
iHOPDOCK7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:32 CEST 2017

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