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DOCK8 (dedicator of cytokinesis 8)

Identity

Other namesMRD2
ZIR8
HGNC (Hugo) DOCK8
LocusID (NCBI) 81704
Location 9p24.3
Location_base_pair Starts at 273048 and ends at 465259 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)DOCK8   19191
Entrez_Gene (NCBI)DOCK8  81704  dedicator of cytokinesis 8
Cards
GeneCards (Weizmann)DOCK8
Ensembl (Hinxton)ENSG00000107099 [Gene_View]  chr9:273048-465259 [Contig_View]  DOCK8 [Vega]
AceView (NCBI)DOCK8
Genatlas (Paris)DOCK8
SOURCE (Stanford)NM_001190458 NM_001193536 NM_203447
Genomic and cartography
GoldenPath (UCSC)DOCK8  -  9p24.3   chr9:273048-465259 +  9p24.3   [Description]    (hg19-Feb_2009)
EnsemblDOCK8 - 9p24.3 [CytoView]
Mapping of homologs : NCBIDOCK8 [Mapview]
OMIM243700   611432   614113   
Gene and transcription
Genbank (Entrez)AB191037 AF194407 AK024436 AK074081 AK090429
RefSeq transcript (SRS)NM_001190458 NM_001193536 NM_203447
RefSeq transcript (Entrez)NM_001190458 NM_001193536 NM_203447
RefSeq genomic (SRS)AC_000141 NC_000009 NC_018920 NG_017007 NT_008413 NW_001839149 NW_004078038
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NG_017007 NT_008413 NW_001839149 NW_004078038
Consensus coding sequences : CCDS (NCBI)DOCK8
Cluster EST : UnigeneHs.132599 [ SRS ] Hs.132599 [ NCBI ]
CGAP (NCI)Hs.132599
Alternative Splicing : Fast-db (Paris)GSHG0029976
Alternative Splicing GalleryENSG00000107099
Gene ExpressionDOCK8 [ NCBI-GEO ]   DOCK8 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NF50 (SRS) Q8NF50 (Uniprot)
NextProtQ8NF50
With graphics : InterProQ8NF50
Splice isoforms : SwissVarQ8NF50(Swissvar)
Domaine pattern : Prosite (SRS)DHR_1 (PS51650)    DHR_2 (PS51651)   
Domaine pattern : Prosite (Expaxy)DHR_1 (PS51650)    DHR_2 (PS51651)   
Domains : Interpro (SRS)ARM-type_fold    DOCK    DOCK_C    DOCK_C/D_N    DOCK_C_fam   
Domains : Interpro (EBI)ARM-type_fold    DOCK    DOCK_C    DOCK_C/D_N    DOCK_C_fam   
Related proteins : CluSTrQ8NF50
Domain families : Pfam (SRS)Ded_cyto (PF06920)    DUF3398 (PF11878)   
Domain families : Pfam (Sanger)Ded_cyto (PF06920)    DUF3398 (PF11878)   
Domain families : Pfam (NCBI)pfam06920    pfam11878   
DMDM81704
Blocks (Seattle)Q8NF50
Human Protein AtlasENSG00000107099
HPRD10920
IPIIPI00797373   IPI00856108   IPI00942335   IPI01025533   IPI00657658   IPI00945909   IPI00946711   IPI00973254   IPI00946073   IPI00945728   IPI00977252   
Protein Interaction databases
DIP (DOE-UCLA)Q8NF50
IntAct (EBI)Q8NF50
FunCoupENSG00000107099
REACTOMEDOCK8
Protein Interaction Database81704
BioGRIDDOCK8
InParanoidQ8NF50
Interologous Interaction database Q8NF50
IntegromeDBDOCK8
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DOCK8
SNP (GeneSNP Utah)DOCK8
SNP : HGBaseDOCK8
Genetic variants : HAPMAPDOCK8
Somatic Mutations in Cancer : COSMICDOCK8 
CONAN: Copy Number AnalysisDOCK8 
Mutations and Diseases : HGMDDOCK8
OMIM243700    611432    614113   
GENETests243700    611432    614113   
Disease Genetic AssociationDOCK8
Huge Navigator DOCK8 [HugePedia]  DOCK8 [HugeCancerGEM]
Genomic VariantsDOCK8  DOCK8 [DGVbeta]
snp3D : Map Gene to Disease81704
General knowledge
Homologs : HomoloGeneDOCK8
Homology/Alignments : Family Browser (UCSC)DOCK8
Phylogenetic Trees/Animal Genes : TreeFamDOCK8
Chemical/Protein Interactions : CTD81704
Chemical/Pharm GKB GenePA134918866
Clinical trialDOCK8
Cancer Resource (Charite)ENSG00000107099
Ontology : AmiGOguanyl-nucleotide exchange factor activity  cytosol  small GTPase mediated signal transduction  blood coagulation  
Ontology : EGO-EBIguanyl-nucleotide exchange factor activity  cytosol  small GTPase mediated signal transduction  blood coagulation  
Other databases
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
PubGeneDOCK8
iHOPDOCK8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:23:28 CEST 2013
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