Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79930
MIM: 611435
HGNC: 24583
Ensembl: ENSG00000146094
Variants:
dbSNP: 79930
ClinVar: 79930
TCGA: ENSG00000146094
COSMIC: DOK3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37235715 | 2023 | Expression and clinical significance of DOK3 in renal clear cell carcinoma. | 0 |
| 37906628 | 2023 | DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11. | 1 |
| 37235715 | 2023 | Expression and clinical significance of DOK3 in renal clear cell carcinoma. | 0 |
| 37906628 | 2023 | DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11. | 1 |
| 36172386 | 2022 | Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein. | 2 |
| 36210538 | 2022 | Porphyromonas gingivalis Activation of Tumor-Associated Macrophages via DOK3 Promotes Recurrence of Oral Squamous Cell Carcinoma. | 3 |
| 36172386 | 2022 | Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein. | 2 |
| 36210538 | 2022 | Porphyromonas gingivalis Activation of Tumor-Associated Macrophages via DOK3 Promotes Recurrence of Oral Squamous Cell Carcinoma. | 3 |
| 32193105 | 2020 | Elevated expression of DOK3 indicates high suppressive immune cell infiltration and unfavorable prognosis of gliomas. | 7 |
| 32193105 | 2020 | Elevated expression of DOK3 indicates high suppressive immune cell infiltration and unfavorable prognosis of gliomas. | 7 |
| 26585945 | 2016 | Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer. | 5 |
| 27265473 | 2016 | Expression of DOK1, 2, and 3 genes in HTLV-1-infected T cells. | 3 |
| 26585945 | 2016 | Searching for candidate genes in familial BRCAX mutation carriers with prostate cancer. | 5 |
| 27265473 | 2016 | Expression of DOK1, 2, and 3 genes in HTLV-1-infected T cells. | 3 |
| 23223229 | 2013 | The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters. | 11 |
Citation
Dessen P
DOK3 (docking protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-05-01
Online version: http://atlasgeneticsoncology.org/gene/51481/dok3
