Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DOK3 (docking protein 3)

Identity

Alias_symbol (synonym)FLJ22570
Other aliasDOKL
HGNC (Hugo) DOK3
LocusID (NCBI) 79930
Atlas_Id 51481
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 177501905 and ends at 177510426 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DOK3 (5q35.3) / ACACA (17q12)NIN (14q22.1) / DOK3 (5q35.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOK3   24583
Cards
Entrez_Gene (NCBI)DOK3  79930  docking protein 3
AliasesDOKL
GeneCards (Weizmann)DOK3
Ensembl hg19 (Hinxton)ENSG00000146094 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146094 [Gene_View]  chr5:177501905-177510426 [Contig_View]  DOK3 [Vega]
ICGC DataPortalENSG00000146094
TCGA cBioPortalDOK3
AceView (NCBI)DOK3
Genatlas (Paris)DOK3
WikiGenes79930
SOURCE (Princeton)DOK3
Genetics Home Reference (NIH)DOK3
Genomic and cartography
GoldenPath hg38 (UCSC)DOK3  -     chr5:177501905-177510426 -  5q35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DOK3  -     5q35.3   [Description]    (hg19-Feb_2009)
EnsemblDOK3 - 5q35.3 [CytoView hg19]  DOK3 - 5q35.3 [CytoView hg38]
Mapping of homologs : NCBIDOK3 [Mapview hg19]  DOK3 [Mapview hg38]
OMIM611435   
Gene and transcription
Genbank (Entrez)AK026223 AK097258 AK307300 AL583057 AL833678
RefSeq transcript (Entrez)NM_001144875 NM_001144876 NM_001308235 NM_001308236 NM_024872
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DOK3
Cluster EST : UnigeneHs.720849 [ NCBI ]
CGAP (NCI)Hs.720849
Alternative Splicing GalleryENSG00000146094
Gene ExpressionDOK3 [ NCBI-GEO ]   DOK3 [ EBI - ARRAY_EXPRESS ]   DOK3 [ SEEK ]   DOK3 [ MEM ]
Gene Expression Viewer (FireBrowse)DOK3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79930
GTEX Portal (Tissue expression)DOK3
Human Protein AtlasENSG00000146094-DOK3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L591   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L591  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L591
Splice isoforms : SwissVarQ7L591
PhosPhoSitePlusQ7L591
Domaine pattern : Prosite (Expaxy)IRS_PTB (PS51064)   
Domains : Interpro (EBI)IRS_PTB    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)IRS (PF02174)   
Domain families : Pfam (NCBI)pfam02174   
Domain families : Smart (EMBL)PH (SM00233)  PTBI (SM00310)  
Conserved Domain (NCBI)DOK3
DMDM Disease mutations79930
Blocks (Seattle)DOK3
SuperfamilyQ7L591
Human Protein Atlas [tissue]ENSG00000146094-DOK3 [tissue]
Peptide AtlasQ7L591
HPRD16834
IPIIPI00156649   IPI00556080   IPI00449361   IPI00028280   IPI00384677   IPI00965932   IPI01008808   IPI00966722   IPI00966425   IPI00965421   IPI00964625   IPI00967061   
Protein Interaction databases
DIP (DOE-UCLA)Q7L591
IntAct (EBI)Q7L591
FunCoupENSG00000146094
BioGRIDDOK3
STRING (EMBL)DOK3
ZODIACDOK3
Ontologies - Pathways
QuickGOQ7L591
Ontology : AmiGOinsulin receptor binding  protein binding  plasma membrane  Ras protein signal transduction  secretory granule membrane  neutrophil degranulation  ficolin-1-rich granule membrane  
Ontology : EGO-EBIinsulin receptor binding  protein binding  plasma membrane  Ras protein signal transduction  secretory granule membrane  neutrophil degranulation  ficolin-1-rich granule membrane  
NDEx NetworkDOK3
Atlas of Cancer Signalling NetworkDOK3
Wikipedia pathwaysDOK3
Orthology - Evolution
OrthoDB79930
GeneTree (enSembl)ENSG00000146094
Phylogenetic Trees/Animal Genes : TreeFamDOK3
HOVERGENQ7L591
HOGENOMQ7L591
Homologs : HomoloGeneDOK3
Homology/Alignments : Family Browser (UCSC)DOK3
Gene fusions - Rearrangements
Tumor Fusion PortalDOK3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOK3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOK3
dbVarDOK3
ClinVarDOK3
1000_GenomesDOK3 
Exome Variant ServerDOK3
ExAC (Exome Aggregation Consortium)ENSG00000146094
GNOMAD BrowserENSG00000146094
Genetic variants : HAPMAP79930
Genomic Variants (DGV)DOK3 [DGVbeta]
DECIPHERDOK3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDOK3 
Mutations
ICGC Data PortalDOK3 
TCGA Data PortalDOK3 
Broad Tumor PortalDOK3
OASIS PortalDOK3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOK3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOK3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOK3
DgiDB (Drug Gene Interaction Database)DOK3
DoCM (Curated mutations)DOK3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOK3 (select a term)
intoGenDOK3
Cancer3DDOK3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611435   
Orphanet
DisGeNETDOK3
MedgenDOK3
Genetic Testing Registry DOK3
NextProtQ7L591 [Medical]
TSGene79930
GENETestsDOK3
Target ValidationDOK3
Huge Navigator DOK3 [HugePedia]
snp3D : Map Gene to Disease79930
BioCentury BCIQDOK3
ClinGenDOK3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79930
Chemical/Pharm GKB GenePA128394725
Clinical trialDOK3
Miscellaneous
canSAR (ICR)DOK3 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOK3
EVEXDOK3
GoPubMedDOK3
iHOPDOK3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:11:02 CET 2017

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