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DOK4 (docking protein 4)

Identity

Alias_symbol (synonym)FLJ10488
Other aliasIRS-5
IRS5
HGNC (Hugo) DOK4
LocusID (NCBI) 55715
Atlas_Id 50679
Location 16q21  [Link to chromosome band 16q21]
Location_base_pair Starts at 57505870 and ends at 57520385 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOK4   19868
Cards
Entrez_Gene (NCBI)DOK4  55715  docking protein 4
AliasesIRS-5; IRS5
GeneCards (Weizmann)DOK4
Ensembl hg19 (Hinxton)ENSG00000125170 [Gene_View]  chr16:57505870-57520385 [Contig_View]  DOK4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000125170 [Gene_View]  chr16:57505870-57520385 [Contig_View]  DOK4 [Vega]
ICGC DataPortalENSG00000125170
TCGA cBioPortalDOK4
AceView (NCBI)DOK4
Genatlas (Paris)DOK4
WikiGenes55715
SOURCE (Princeton)DOK4
Genetics Home Reference (NIH)DOK4
Genomic and cartography
GoldenPath hg19 (UCSC)DOK4  -     chr16:57505870-57520385 -  16q21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DOK4  -     16q21   [Description]    (hg38-Dec_2013)
EnsemblDOK4 - 16q21 [CytoView hg19]  DOK4 - 16q21 [CytoView hg38]
Mapping of homologs : NCBIDOK4 [Mapview hg19]  DOK4 [Mapview hg38]
OMIM608333   
Gene and transcription
Genbank (Entrez)AF466369 AK001350 AK307270 AK315426 AW163719
RefSeq transcript (Entrez)NM_018110
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)DOK4
Cluster EST : UnigeneHs.279832 [ NCBI ]
CGAP (NCI)Hs.279832
Alternative Splicing GalleryENSG00000125170
Gene ExpressionDOK4 [ NCBI-GEO ]   DOK4 [ EBI - ARRAY_EXPRESS ]   DOK4 [ SEEK ]   DOK4 [ MEM ]
Gene Expression Viewer (FireBrowse)DOK4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55715
GTEX Portal (Tissue expression)DOK4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEW6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEW6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEW6
Splice isoforms : SwissVarQ8TEW6
PhosPhoSitePlusQ8TEW6
Domaine pattern : Prosite (Expaxy)IRS_PTB (PS51064)   
Domains : Interpro (EBI)IRS_PTB    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)IRS (PF02174)   
Domain families : Pfam (NCBI)pfam02174   
Domain families : Smart (EMBL)PH (SM00233)  PTBI (SM00310)  
Conserved Domain (NCBI)DOK4
DMDM Disease mutations55715
Blocks (Seattle)DOK4
SuperfamilyQ8TEW6
Human Protein AtlasENSG00000125170
Peptide AtlasQ8TEW6
HPRD16316
IPIIPI00550728   
Protein Interaction databases
DIP (DOE-UCLA)Q8TEW6
IntAct (EBI)Q8TEW6
FunCoupENSG00000125170
BioGRIDDOK4
STRING (EMBL)DOK4
ZODIACDOK4
Ontologies - Pathways
QuickGOQ8TEW6
Ontology : AmiGOMAPK cascade  receptor signaling protein activity  insulin receptor binding  protein binding  intracellular  transmembrane receptor protein tyrosine kinase signaling pathway  nervous system development  
Ontology : EGO-EBIMAPK cascade  receptor signaling protein activity  insulin receptor binding  protein binding  intracellular  transmembrane receptor protein tyrosine kinase signaling pathway  nervous system development  
NDEx NetworkDOK4
Atlas of Cancer Signalling NetworkDOK4
Wikipedia pathwaysDOK4
Orthology - Evolution
OrthoDB55715
GeneTree (enSembl)ENSG00000125170
Phylogenetic Trees/Animal Genes : TreeFamDOK4
HOVERGENQ8TEW6
HOGENOMQ8TEW6
Homologs : HomoloGeneDOK4
Homology/Alignments : Family Browser (UCSC)DOK4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOK4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOK4
dbVarDOK4
ClinVarDOK4
1000_GenomesDOK4 
Exome Variant ServerDOK4
ExAC (Exome Aggregation Consortium)DOK4 (select the gene name)
Genetic variants : HAPMAP55715
Genomic Variants (DGV)DOK4 [DGVbeta]
DECIPHER (Syndromes)16:57505870-57520385  ENSG00000125170
CONAN: Copy Number AnalysisDOK4 
Mutations
ICGC Data PortalDOK4 
TCGA Data PortalDOK4 
Broad Tumor PortalDOK4
OASIS PortalDOK4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOK4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOK4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOK4
DgiDB (Drug Gene Interaction Database)DOK4
DoCM (Curated mutations)DOK4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOK4 (select a term)
intoGenDOK4
Cancer3DDOK4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608333   
Orphanet
MedgenDOK4
Genetic Testing Registry DOK4
NextProtQ8TEW6 [Medical]
TSGene55715
GENETestsDOK4
Huge Navigator DOK4 [HugePedia]
snp3D : Map Gene to Disease55715
BioCentury BCIQDOK4
ClinGenDOK4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55715
Chemical/Pharm GKB GenePA134892921
Clinical trialDOK4
Miscellaneous
canSAR (ICR)DOK4 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOK4
EVEXDOK4
GoPubMedDOK4
iHOPDOK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:44 CET 2017

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