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DOK7 (docking protein 7)

Identity

Alias_namesC4orf25
chromosome 4 open reading frame 25
Alias_symbol (synonym)FLJ33718
FLJ39137
Dok-7
HGNC (Hugo) DOK7
LocusID (NCBI) 285489
Atlas_Id 53213
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 3465033 and ends at 3496209 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZRANB2-AS1 (1p31.1) / DOK7 (4p16.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOK7   26594
LRG (Locus Reference Genomic)LRG_869
Cards
Entrez_Gene (NCBI)DOK7  285489  docking protein 7
AliasesC4orf25; CMS10; CMS1B
GeneCards (Weizmann)DOK7
Ensembl hg19 (Hinxton)ENSG00000175920 [Gene_View]  chr4:3465033-3496209 [Contig_View]  DOK7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000175920 [Gene_View]  chr4:3465033-3496209 [Contig_View]  DOK7 [Vega]
ICGC DataPortalENSG00000175920
TCGA cBioPortalDOK7
AceView (NCBI)DOK7
Genatlas (Paris)DOK7
WikiGenes285489
SOURCE (Princeton)DOK7
Genetics Home Reference (NIH)DOK7
Genomic and cartography
GoldenPath hg19 (UCSC)DOK7  -     chr4:3465033-3496209 +  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DOK7  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblDOK7 - 4p16.3 [CytoView hg19]  DOK7 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIDOK7 [Mapview hg19]  DOK7 [Mapview hg38]
OMIM208150   254300   610285   
Gene and transcription
Genbank (Entrez)AB220918 AK075037 AK091037 AK096456 BC043568
RefSeq transcript (Entrez)NM_001164673 NM_001256896 NM_001301071 NM_173660
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_013072 NT_006051 NW_004929314
Consensus coding sequences : CCDS (NCBI)DOK7
Cluster EST : UnigeneHs.701584 [ NCBI ]
CGAP (NCI)Hs.701584
Alternative Splicing GalleryENSG00000175920
Gene ExpressionDOK7 [ NCBI-GEO ]   DOK7 [ EBI - ARRAY_EXPRESS ]   DOK7 [ SEEK ]   DOK7 [ MEM ]
Gene Expression Viewer (FireBrowse)DOK7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285489
GTEX Portal (Tissue expression)DOK7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ18PE1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ18PE1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ18PE1
Splice isoforms : SwissVarQ18PE1
PhosPhoSitePlusQ18PE1
Domaine pattern : Prosite (Expaxy)IRS_PTB (PS51064)    PH_DOMAIN (PS50003)   
Domains : Interpro (EBI)IRS_PTB    PH_dom-like    PH_domain   
Domain families : Pfam (Sanger)IRS (PF02174)   
Domain families : Pfam (NCBI)pfam02174   
Domain families : Smart (EMBL)PH (SM00233)  
Conserved Domain (NCBI)DOK7
DMDM Disease mutations285489
Blocks (Seattle)DOK7
SuperfamilyQ18PE1
Human Protein AtlasENSG00000175920
Peptide AtlasQ18PE1
HPRD08744
IPIIPI00783590   IPI00168218   IPI00783555   IPI00383898   IPI00944456   
Protein Interaction databases
DIP (DOE-UCLA)Q18PE1
IntAct (EBI)Q18PE1
FunCoupENSG00000175920
BioGRIDDOK7
STRING (EMBL)DOK7
ZODIACDOK7
Ontologies - Pathways
QuickGOQ18PE1
Ontology : AmiGOinsulin receptor binding  plasma membrane  lipid binding  protein kinase binding  cell junction  synapse  positive regulation of protein tyrosine kinase activity  
Ontology : EGO-EBIinsulin receptor binding  plasma membrane  lipid binding  protein kinase binding  cell junction  synapse  positive regulation of protein tyrosine kinase activity  
NDEx NetworkDOK7
Atlas of Cancer Signalling NetworkDOK7
Wikipedia pathwaysDOK7
Orthology - Evolution
OrthoDB285489
GeneTree (enSembl)ENSG00000175920
Phylogenetic Trees/Animal Genes : TreeFamDOK7
HOVERGENQ18PE1
HOGENOMQ18PE1
Homologs : HomoloGeneDOK7
Homology/Alignments : Family Browser (UCSC)DOK7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOK7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOK7
dbVarDOK7
ClinVarDOK7
1000_GenomesDOK7 
Exome Variant ServerDOK7
ExAC (Exome Aggregation Consortium)DOK7 (select the gene name)
Genetic variants : HAPMAP285489
Genomic Variants (DGV)DOK7 [DGVbeta]
DECIPHER (Syndromes)4:3465033-3496209  ENSG00000175920
CONAN: Copy Number AnalysisDOK7 
Mutations
ICGC Data PortalDOK7 
TCGA Data PortalDOK7 
Broad Tumor PortalDOK7
OASIS PortalDOK7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOK7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOK7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DOK7
DgiDB (Drug Gene Interaction Database)DOK7
DoCM (Curated mutations)DOK7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOK7 (select a term)
intoGenDOK7
Cancer3DDOK7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM208150    254300    610285   
Orphanet1310    13930   
MedgenDOK7
Genetic Testing Registry DOK7
NextProtQ18PE1 [Medical]
TSGene285489
GENETestsDOK7
Huge Navigator DOK7 [HugePedia]
snp3D : Map Gene to Disease285489
BioCentury BCIQDOK7
ClinGenDOK7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285489
Chemical/Pharm GKB GenePA162384035
Clinical trialDOK7
Miscellaneous
canSAR (ICR)DOK7 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOK7
EVEXDOK7
GoPubMedDOK7
iHOPDOK7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Nov 18 19:36:03 CET 2016

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