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DOLK (dolichol kinase)

Identity

Alias_namesTMEM15
transmembrane protein 15
Alias_symbol (synonym)KIAA1094
DK1
Other aliasCDG1M
DK
SEC59
HGNC (Hugo) DOLK
LocusID (NCBI) 22845
Atlas_Id 62596
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 128945530 and ends at 128947733 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DOLK   23406
LRG (Locus Reference Genomic)LRG_744
Cards
Entrez_Gene (NCBI)DOLK  22845  dolichol kinase
AliasesCDG1M; DK; DK1; SEC59; 
TMEM15
GeneCards (Weizmann)DOLK
Ensembl hg19 (Hinxton)ENSG00000175283 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175283 [Gene_View]  chr9:128945530-128947733 [Contig_View]  DOLK [Vega]
ICGC DataPortalENSG00000175283
TCGA cBioPortalDOLK
AceView (NCBI)DOLK
Genatlas (Paris)DOLK
WikiGenes22845
SOURCE (Princeton)DOLK
Genetics Home Reference (NIH)DOLK
Genomic and cartography
GoldenPath hg38 (UCSC)DOLK  -     chr9:128945530-128947733 -  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DOLK  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblDOLK - 9q34.11 [CytoView hg19]  DOLK - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIDOLK [Mapview hg19]  DOLK [Mapview hg38]
OMIM610746   610768   
Gene and transcription
Genbank (Entrez)AB029017 AK225402 AK300180 AY358759 BC035556
RefSeq transcript (Entrez)NM_014908
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DOLK
Cluster EST : UnigeneHs.531563 [ NCBI ]
CGAP (NCI)Hs.531563
Alternative Splicing GalleryENSG00000175283
Gene ExpressionDOLK [ NCBI-GEO ]   DOLK [ EBI - ARRAY_EXPRESS ]   DOLK [ SEEK ]   DOLK [ MEM ]
Gene Expression Viewer (FireBrowse)DOLK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22845
GTEX Portal (Tissue expression)DOLK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPQ8
Splice isoforms : SwissVarQ9UPQ8
Catalytic activity : Enzyme2.7.1.108 [ Enzyme-Expasy ]   2.7.1.1082.7.1.108 [ IntEnz-EBI ]   2.7.1.108 [ BRENDA ]   2.7.1.108 [ KEGG ]   
PhosPhoSitePlusQ9UPQ8
Domains : Interpro (EBI)Polypren_kinase   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)DOLK
DMDM Disease mutations22845
Blocks (Seattle)DOLK
SuperfamilyQ9UPQ8
Human Protein AtlasENSG00000175283
Peptide AtlasQ9UPQ8
HPRD15525
IPIIPI00007165   IPI01010617   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPQ8
IntAct (EBI)Q9UPQ8
FunCoupENSG00000175283
BioGRIDDOLK
STRING (EMBL)DOLK
ZODIACDOLK
Ontologies - Pathways
QuickGOQ9UPQ8
Ontology : AmiGOdolichol kinase activity  dolichol kinase activity  protein binding  endoplasmic reticulum membrane  protein glycosylation  dolichyl diphosphate biosynthetic process  phosphorylation  integral component of endoplasmic reticulum membrane  dolichyl monophosphate biosynthetic process  
Ontology : EGO-EBIdolichol kinase activity  dolichol kinase activity  protein binding  endoplasmic reticulum membrane  protein glycosylation  dolichyl diphosphate biosynthetic process  phosphorylation  integral component of endoplasmic reticulum membrane  dolichyl monophosphate biosynthetic process  
Pathways : KEGGN-Glycan biosynthesis   
NDEx NetworkDOLK
Atlas of Cancer Signalling NetworkDOLK
Wikipedia pathwaysDOLK
Orthology - Evolution
OrthoDB22845
GeneTree (enSembl)ENSG00000175283
Phylogenetic Trees/Animal Genes : TreeFamDOLK
HOVERGENQ9UPQ8
HOGENOMQ9UPQ8
Homologs : HomoloGeneDOLK
Homology/Alignments : Family Browser (UCSC)DOLK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDOLK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DOLK
dbVarDOLK
ClinVarDOLK
1000_GenomesDOLK 
Exome Variant ServerDOLK
ExAC (Exome Aggregation Consortium)DOLK (select the gene name)
Genetic variants : HAPMAP22845
Genomic Variants (DGV)DOLK [DGVbeta]
DECIPHERDOLK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDOLK 
Mutations
ICGC Data PortalDOLK 
TCGA Data PortalDOLK 
Broad Tumor PortalDOLK
OASIS PortalDOLK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDOLK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDOLK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DOLK
DgiDB (Drug Gene Interaction Database)DOLK
DoCM (Curated mutations)DOLK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DOLK (select a term)
intoGenDOLK
Cancer3DDOLK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610746    610768   
Orphanet635    12108   
MedgenDOLK
Genetic Testing Registry DOLK
NextProtQ9UPQ8 [Medical]
TSGene22845
GENETestsDOLK
Target ValidationDOLK
Huge Navigator DOLK [HugePedia]
snp3D : Map Gene to Disease22845
BioCentury BCIQDOLK
ClinGenDOLK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22845
Chemical/Pharm GKB GenePA162384054
Clinical trialDOLK
Miscellaneous
canSAR (ICR)DOLK (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDOLK
EVEXDOLK
GoPubMedDOLK
iHOPDOLK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:46:19 CEST 2017

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