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DPAGT1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1)

Identity

Alias_namesDPAGT2
DPAGT
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
Alias_symbol (synonym)GPT
D11S366
DGPT
ALG7
CDG-Ij
Other aliasCDG1J
CMS13
CMSTA2
G1PT
UAGT
UGAT
HGNC (Hugo) DPAGT1
LocusID (NCBI) 1798
Atlas_Id 51157
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 119096503 and ends at 119102075 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPAGT1   2995
Cards
Entrez_Gene (NCBI)DPAGT1  1798  dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
AliasesALG7; CDG-Ij; CDG1J; CMS13; 
CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT
GeneCards (Weizmann)DPAGT1
Ensembl hg19 (Hinxton)ENSG00000172269 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172269 [Gene_View]  chr11:119096503-119102075 [Contig_View]  DPAGT1 [Vega]
ICGC DataPortalENSG00000172269
TCGA cBioPortalDPAGT1
AceView (NCBI)DPAGT1
Genatlas (Paris)DPAGT1
WikiGenes1798
SOURCE (Princeton)DPAGT1
Genetics Home Reference (NIH)DPAGT1
Genomic and cartography
GoldenPath hg38 (UCSC)DPAGT1  -     chr11:119096503-119102075 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPAGT1  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblDPAGT1 - 11q23.3 [CytoView hg19]  DPAGT1 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIDPAGT1 [Mapview hg19]  DPAGT1 [Mapview hg38]
OMIM191350   608093   614750   
Gene and transcription
Genbank (Entrez)AA833740 AK095122 AK095718 AK128572 AK225994
RefSeq transcript (Entrez)NM_001382 NM_203316
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPAGT1
Cluster EST : UnigeneHs.524081 [ NCBI ]
CGAP (NCI)Hs.524081
Alternative Splicing GalleryENSG00000172269
Gene ExpressionDPAGT1 [ NCBI-GEO ]   DPAGT1 [ EBI - ARRAY_EXPRESS ]   DPAGT1 [ SEEK ]   DPAGT1 [ MEM ]
Gene Expression Viewer (FireBrowse)DPAGT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1798
GTEX Portal (Tissue expression)DPAGT1
Human Protein AtlasENSG00000172269-DPAGT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3H5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3H5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3H5
Splice isoforms : SwissVarQ9H3H5
Catalytic activity : Enzyme2.7.8.15 [ Enzyme-Expasy ]   2.7.8.152.7.8.15 [ IntEnz-EBI ]   2.7.8.15 [ BRENDA ]   2.7.8.15 [ KEGG ]   
PhosPhoSitePlusQ9H3H5
Domains : Interpro (EBI)Glycosyl_transferase_4    GPT   
Domain families : Pfam (Sanger)Glycos_transf_4 (PF00953)   
Domain families : Pfam (NCBI)pfam00953   
Conserved Domain (NCBI)DPAGT1
DMDM Disease mutations1798
Blocks (Seattle)DPAGT1
PDB (SRS)5LEV   
PDB (PDBSum)5LEV   
PDB (IMB)5LEV   
PDB (RSDB)5LEV   
Structural Biology KnowledgeBase5LEV   
SCOP (Structural Classification of Proteins)5LEV   
CATH (Classification of proteins structures)5LEV   
SuperfamilyQ9H3H5
Human Protein Atlas [tissue]ENSG00000172269-DPAGT1 [tissue]
Peptide AtlasQ9H3H5
HPRD01879
IPIIPI00023500   IPI00219736   IPI00394961   IPI00909196   IPI00982494   IPI00917246   IPI00916933   IPI00917933   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3H5
IntAct (EBI)Q9H3H5
FunCoupENSG00000172269
BioGRIDDPAGT1
STRING (EMBL)DPAGT1
ZODIACDPAGT1
Ontologies - Pathways
QuickGOQ9H3H5
Ontology : AmiGOUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  UDP-N-acetylglucosamine metabolic process  protein N-linked glycosylation  dolichol-linked oligosaccharide biosynthetic process  dolichyl diphosphate biosynthetic process  phospho-N-acetylmuramoyl-pentapeptide-transferase activity  membrane  integral component of membrane  integral component of membrane  transferase activity, transferring glycosyl groups  dolichol metabolic process  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  intracellular membrane-bounded organelle  protein oligomerization  
Ontology : EGO-EBIUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity  UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum membrane  UDP-N-acetylglucosamine metabolic process  protein N-linked glycosylation  dolichol-linked oligosaccharide biosynthetic process  dolichyl diphosphate biosynthetic process  phospho-N-acetylmuramoyl-pentapeptide-transferase activity  membrane  integral component of membrane  integral component of membrane  transferase activity, transferring glycosyl groups  dolichol metabolic process  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  intracellular membrane-bounded organelle  protein oligomerization  
Pathways : KEGGN-Glycan biosynthesis   
NDEx NetworkDPAGT1
Atlas of Cancer Signalling NetworkDPAGT1
Wikipedia pathwaysDPAGT1
Orthology - Evolution
OrthoDB1798
GeneTree (enSembl)ENSG00000172269
Phylogenetic Trees/Animal Genes : TreeFamDPAGT1
HOVERGENQ9H3H5
HOGENOMQ9H3H5
Homologs : HomoloGeneDPAGT1
Homology/Alignments : Family Browser (UCSC)DPAGT1
Gene fusions - Rearrangements
Tumor Fusion PortalDPAGT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPAGT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPAGT1
dbVarDPAGT1
ClinVarDPAGT1
1000_GenomesDPAGT1 
Exome Variant ServerDPAGT1
ExAC (Exome Aggregation Consortium)ENSG00000172269
GNOMAD BrowserENSG00000172269
Genetic variants : HAPMAP1798
Genomic Variants (DGV)DPAGT1 [DGVbeta]
DECIPHERDPAGT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPAGT1 
Mutations
ICGC Data PortalDPAGT1 
TCGA Data PortalDPAGT1 
Broad Tumor PortalDPAGT1
OASIS PortalDPAGT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPAGT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPAGT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DPAGT1
DgiDB (Drug Gene Interaction Database)DPAGT1
DoCM (Curated mutations)DPAGT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPAGT1 (select a term)
intoGenDPAGT1
Cancer3DDPAGT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191350    608093    614750   
Orphanet22137    11726   
DisGeNETDPAGT1
MedgenDPAGT1
Genetic Testing Registry DPAGT1
NextProtQ9H3H5 [Medical]
TSGene1798
GENETestsDPAGT1
Target ValidationDPAGT1
Huge Navigator DPAGT1 [HugePedia]
snp3D : Map Gene to Disease1798
BioCentury BCIQDPAGT1
ClinGenDPAGT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1798
Chemical/Pharm GKB GenePA27460
Clinical trialDPAGT1
Miscellaneous
canSAR (ICR)DPAGT1 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPAGT1
EVEXDPAGT1
GoPubMedDPAGT1
iHOPDPAGT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:11:04 CET 2017

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