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DPEP1 (dipeptidase 1 (renal))

Identity

Other aliasMBD1
MDP
RDP
HGNC (Hugo) DPEP1
LocusID (NCBI) 1800
Atlas_Id 46097
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89679716 and ends at 89704839 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANKRD11 (16q24.3) / DPEP1 (16q24.3)SPATA33 (16q24.3) / DPEP1 (16q24.3)ANKRD11 16q24.3 / DPEP1 16q24.3
C16orf55 DPEP1 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPEP1   3002
Cards
Entrez_Gene (NCBI)DPEP1  1800  dipeptidase 1 (renal)
AliasesMBD1; MDP; RDP
GeneCards (Weizmann)DPEP1
Ensembl hg19 (Hinxton)ENSG00000015413 [Gene_View]  chr16:89679716-89704839 [Contig_View]  DPEP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000015413 [Gene_View]  chr16:89679716-89704839 [Contig_View]  DPEP1 [Vega]
ICGC DataPortalENSG00000015413
TCGA cBioPortalDPEP1
AceView (NCBI)DPEP1
Genatlas (Paris)DPEP1
WikiGenes1800
SOURCE (Princeton)DPEP1
Genetics Home Reference (NIH)DPEP1
Genomic and cartography
GoldenPath hg19 (UCSC)DPEP1  -     chr16:89679716-89704839 +  16q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DPEP1  -     16q24.3   [Description]    (hg38-Dec_2013)
EnsemblDPEP1 - 16q24.3 [CytoView hg19]  DPEP1 - 16q24.3 [CytoView hg38]
Mapping of homologs : NCBIDPEP1 [Mapview hg19]  DPEP1 [Mapview hg38]
OMIM179780   
Gene and transcription
Genbank (Entrez)AK309577 BC017023 BM152944 BT006664 CR457404
RefSeq transcript (Entrez)NM_001128141 NM_004413
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929403
Consensus coding sequences : CCDS (NCBI)DPEP1
Cluster EST : UnigeneHs.109 [ NCBI ]
CGAP (NCI)Hs.109
Alternative Splicing GalleryENSG00000015413
Gene ExpressionDPEP1 [ NCBI-GEO ]   DPEP1 [ EBI - ARRAY_EXPRESS ]   DPEP1 [ SEEK ]   DPEP1 [ MEM ]
Gene Expression Viewer (FireBrowse)DPEP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1800
GTEX Portal (Tissue expression)DPEP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16444   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16444  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16444
Splice isoforms : SwissVarP16444
Catalytic activity : Enzyme3.4.13.19 [ Enzyme-Expasy ]   3.4.13.193.4.13.19 [ IntEnz-EBI ]   3.4.13.19 [ BRENDA ]   3.4.13.19 [ KEGG ]   
PhosPhoSitePlusP16444
Domaine pattern : Prosite (Expaxy)RENAL_DIPEPTIDASE_1 (PS00869)    RENAL_DIPEPTIDASE_2 (PS51365)   
Domains : Interpro (EBI)Dipep_AS    Dpep1    Metal_Hydrolase    Renal_dipep_fam   
Domain families : Pfam (Sanger)Peptidase_M19 (PF01244)   
Domain families : Pfam (NCBI)pfam01244   
Conserved Domain (NCBI)DPEP1
DMDM Disease mutations1800
Blocks (Seattle)DPEP1
PDB (SRS)1ITQ    1ITU   
PDB (PDBSum)1ITQ    1ITU   
PDB (IMB)1ITQ    1ITU   
PDB (RSDB)1ITQ    1ITU   
Structural Biology KnowledgeBase1ITQ    1ITU   
SCOP (Structural Classification of Proteins)1ITQ    1ITU   
CATH (Classification of proteins structures)1ITQ    1ITU   
SuperfamilyP16444
Human Protein AtlasENSG00000015413
Peptide AtlasP16444
HPRD01563
IPIIPI00059476   
Protein Interaction databases
DIP (DOE-UCLA)P16444
IntAct (EBI)P16444
FunCoupENSG00000015413
BioGRIDDPEP1
STRING (EMBL)DPEP1
ZODIACDPEP1
Ontologies - Pathways
QuickGOP16444
Ontology : AmiGOprotein binding  extracellular space  plasma membrane  plasma membrane  proteolysis  leukotriene metabolic process  glutathione metabolic process  xenobiotic metabolic process  metalloexopeptidase activity  dipeptidyl-peptidase activity  zinc ion binding  apical plasma membrane  dipeptidase activity  antibiotic metabolic process  negative regulation of cell migration  anchored component of membrane  microvillus membrane  GPI anchor binding  cellular response to drug  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  apical part of cell  homocysteine metabolic process  extracellular exosome  metallodipeptidase activity  cellular response to calcium ion  cellular response to nitric oxide  cellular lactam catabolic process  modified amino acid binding  
Ontology : EGO-EBIprotein binding  extracellular space  plasma membrane  plasma membrane  proteolysis  leukotriene metabolic process  glutathione metabolic process  xenobiotic metabolic process  metalloexopeptidase activity  dipeptidyl-peptidase activity  zinc ion binding  apical plasma membrane  dipeptidase activity  antibiotic metabolic process  negative regulation of cell migration  anchored component of membrane  microvillus membrane  GPI anchor binding  cellular response to drug  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  negative regulation of apoptotic process  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  apical part of cell  homocysteine metabolic process  extracellular exosome  metallodipeptidase activity  cellular response to calcium ion  cellular response to nitric oxide  cellular lactam catabolic process  modified amino acid binding  
NDEx NetworkDPEP1
Atlas of Cancer Signalling NetworkDPEP1
Wikipedia pathwaysDPEP1
Orthology - Evolution
OrthoDB1800
GeneTree (enSembl)ENSG00000015413
Phylogenetic Trees/Animal Genes : TreeFamDPEP1
HOVERGENP16444
HOGENOMP16444
Homologs : HomoloGeneDPEP1
Homology/Alignments : Family Browser (UCSC)DPEP1
Gene fusions - Rearrangements
Fusion : MitelmanANKRD11/DPEP1 [16q24.3/16q24.3]  [t(16;16)(q24;q24)]  
Fusion : MitelmanSPATA33/DPEP1 [16q24.3/16q24.3]  [t(16;16)(q24;q24)]  
Fusion: TCGAANKRD11 16q24.3 DPEP1 16q24.3 THCA
Fusion: TCGAC16orf55 DPEP1 16q24.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPEP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPEP1
dbVarDPEP1
ClinVarDPEP1
1000_GenomesDPEP1 
Exome Variant ServerDPEP1
ExAC (Exome Aggregation Consortium)DPEP1 (select the gene name)
Genetic variants : HAPMAP1800
Genomic Variants (DGV)DPEP1 [DGVbeta]
DECIPHER (Syndromes)16:89679716-89704839  ENSG00000015413
CONAN: Copy Number AnalysisDPEP1 
Mutations
ICGC Data PortalDPEP1 
TCGA Data PortalDPEP1 
Broad Tumor PortalDPEP1
OASIS PortalDPEP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPEP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPEP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPEP1
DgiDB (Drug Gene Interaction Database)DPEP1
DoCM (Curated mutations)DPEP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPEP1 (select a term)
intoGenDPEP1
Cancer3DDPEP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM179780   
Orphanet
MedgenDPEP1
Genetic Testing Registry DPEP1
NextProtP16444 [Medical]
TSGene1800
GENETestsDPEP1
Huge Navigator DPEP1 [HugePedia]
snp3D : Map Gene to Disease1800
BioCentury BCIQDPEP1
ClinGenDPEP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1800
Chemical/Pharm GKB GenePA144
Clinical trialDPEP1
Miscellaneous
canSAR (ICR)DPEP1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPEP1
EVEXDPEP1
GoPubMedDPEP1
iHOPDPEP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:45 CET 2017

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