Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DPF2 (double PHD fingers 2)

Identity

Alias (NCBI)CSS7
REQ
SMARCG2
UBID4
ubi-d4
HGNC (Hugo) DPF2
HGNC Alias symbubi-d4
BAF45d
HGNC Previous nameREQ
HGNC Previous namerequiem, apoptosis response zinc finger gene
 D4, zinc and double PHD fingers family 2
LocusID (NCBI) 5977
Atlas_Id 40358
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 65333852 and ends at 65354262 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DPF2 (11q13.1)::POLA2 (11q13.1)DPF2 (11q13.1)::SART1 (11q13.1)DPF2 (11q13.1)::TRIM49C (11q14.3)
FRMD8 (11q13.1)::DPF2 (11q13.1)METTL12 (11q12.3)::DPF2 (11q13.1)ZNHIT1 (7q22.1)::DPF2 (11q13.1)
DPF2 11q13.1::POLA2 11q13.1DPF2 11q13.1 TRIM49L2FRMD8 11q13.1::DPF2 11q13.1
METTL12 11q12.3::DPF2 11q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DPF2   9964
Cards
Entrez_Gene (NCBI)DPF2    double PHD fingers 2
AliasesCSS7; REQ; SMARCG2; UBID4; 
ubi-d4
GeneCards (Weizmann)DPF2
Ensembl hg19 (Hinxton)ENSG00000133884 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133884 [Gene_View]  ENSG00000133884 [Sequence]  chr11:65333852-65354262 [Contig_View]  DPF2 [Vega]
ICGC DataPortalENSG00000133884
TCGA cBioPortalDPF2
AceView (NCBI)DPF2
Genatlas (Paris)DPF2
SOURCE (Princeton)DPF2
Genetics Home Reference (NIH)DPF2
Genomic and cartography
GoldenPath hg38 (UCSC)DPF2  -     chr11:65333852-65354262 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPF2  -     11q13.1   [Description]    (hg19-Feb_2009)
GoldenPathDPF2 - 11q13.1 [CytoView hg19]  DPF2 - 11q13.1 [CytoView hg38]
ImmunoBaseENSG00000133884
Genome Data Viewer NCBIDPF2 [Mapview hg19]  
OMIM601671   618027   
Gene and transcription
Genbank (Entrez)AF001433 AI381588 AK096796 AK291944 AK300061
RefSeq transcript (Entrez)NM_001330308 NM_006268
Consensus coding sequences : CCDS (NCBI)DPF2
Gene ExpressionDPF2 [ NCBI-GEO ]   DPF2 [ EBI - ARRAY_EXPRESS ]   DPF2 [ SEEK ]   DPF2 [ MEM ]
Gene Expression Viewer (FireBrowse)DPF2 [ Firebrowse - Broad ]
GenevisibleExpression of DPF2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5977
GTEX Portal (Tissue expression)DPF2
Human Protein AtlasENSG00000133884-DPF2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92785   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92785  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92785
PhosPhoSitePlusQ92785
Domaine pattern : Prosite (Expaxy)ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Requiem/DPF_N_dom    Znf_C2H2_sf    Znf_C2H2_type    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PHD (PF00628)    Requiem_N (PF14051)   
Domain families : Pfam (NCBI)pfam00628    pfam14051   
Domain families : Smart (EMBL)PHD (SM00249)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)DPF2
PDB (RSDB)3IUF    5B79    5VDC    6LTH    6LTJ   
PDB Europe3IUF    5B79    5VDC    6LTH    6LTJ   
PDB (PDBSum)3IUF    5B79    5VDC    6LTH    6LTJ   
PDB (IMB)3IUF    5B79    5VDC    6LTH    6LTJ   
Structural Biology KnowledgeBase3IUF    5B79    5VDC    6LTH    6LTJ   
SCOP (Structural Classification of Proteins)3IUF    5B79    5VDC    6LTH    6LTJ   
CATH (Classification of proteins structures)3IUF    5B79    5VDC    6LTH    6LTJ   
SuperfamilyQ92785
AlphaFold pdb e-kbQ92785   
Human Protein Atlas [tissue]ENSG00000133884-DPF2 [tissue]
HPRD03394
Protein Interaction databases
DIP (DOE-UCLA)Q92785
IntAct (EBI)Q92785
BioGRIDDPF2
STRING (EMBL)DPF2
ZODIACDPF2
Ontologies - Pathways
QuickGOQ92785
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  chromatin  transcription coregulator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  centrosome  cytosol  apoptotic process  nervous system development  histone binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  H3K9me3 modified histone binding  lysine-acetylated histone binding  nBAF complex  apoptotic signaling pathway  negative regulation of myeloid progenitor cell differentiation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  chromatin  transcription coregulator activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  centrosome  cytosol  apoptotic process  nervous system development  histone binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  metal ion binding  H3K9me3 modified histone binding  lysine-acetylated histone binding  nBAF complex  apoptotic signaling pathway  negative regulation of myeloid progenitor cell differentiation  
Pathways : BIOCARTABIOCARTA_BCELLSURVIVALPATHWAY   
NDEx NetworkDPF2
Atlas of Cancer Signalling NetworkDPF2
Wikipedia pathwaysDPF2
Orthology - Evolution
OrthoDB5977
GeneTree (enSembl)ENSG00000133884
Phylogenetic Trees/Animal Genes : TreeFamDPF2
Homologs : HomoloGeneDPF2
Homology/Alignments : Family Browser (UCSC)DPF2
Gene fusions - Rearrangements
Fusion : MitelmanDPF2::POLA2 [11q13.1/11q13.1]  
Fusion : MitelmanDPF2::TRIM49C [11q13.1/11q14.3]  
Fusion : MitelmanFRMD8::DPF2 [11q13.1/11q13.1]  
Fusion : MitelmanMETTL12::DPF2 [11q12.3/11q13.1]  
Fusion : QuiverDPF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPF2
dbVarDPF2
ClinVarDPF2
MonarchDPF2
1000_GenomesDPF2 
Exome Variant ServerDPF2
GNOMAD BrowserENSG00000133884
Varsome BrowserDPF2
ACMGDPF2 variants
VarityQ92785
Genomic Variants (DGV)DPF2 [DGVbeta]
DECIPHERDPF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPF2 
Mutations
ICGC Data PortalDPF2 
TCGA Data PortalDPF2 
Broad Tumor PortalDPF2
OASIS PortalDPF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPF2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDPF2
Mutations and Diseases : HGMDDPF2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDPF2
DgiDB (Drug Gene Interaction Database)DPF2
DoCM (Curated mutations)DPF2
CIViC (Clinical Interpretations of Variants in Cancer)DPF2
Cancer3DDPF2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601671    618027   
Orphanet321   
DisGeNETDPF2
MedgenDPF2
Genetic Testing Registry DPF2
NextProtQ92785 [Medical]
GENETestsDPF2
Target ValidationDPF2
Huge Navigator DPF2 [HugePedia]
ClinGenDPF2
Clinical trials, drugs, therapy
MyCancerGenomeDPF2
Protein Interactions : CTDDPF2
Pharm GKB GenePA34331
PharosQ92785
Clinical trialDPF2
Miscellaneous
canSAR (ICR)DPF2
HarmonizomeDPF2
ARCHS4DPF2
DataMed IndexDPF2
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDPF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 12:31:07 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.