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DPH3 (diphthamide biosynthesis 3)

Identity

Alias_namesKTI11 homolog A (S. cerevisiae)
ZCSL2
Alias_symbol (synonym)DESR1
DELGIP1
MGC20197
KTI11
DELGIP
DPH3A
Other alias
HGNC (Hugo) DPH3
LocusID (NCBI) 285381
Atlas_Id 43559
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 16298568 and ends at 16306496 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MAGI1 (3p14.1) / DPH3 (3p25.1)MAGI1 3p14.1 / DPH3 3p25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPH3   27717
Cards
Entrez_Gene (NCBI)DPH3  285381  diphthamide biosynthesis 3
AliasesDELGIP; DELGIP1; DESR1; DPH3A; 
KTI11; ZCSL2
GeneCards (Weizmann)DPH3
Ensembl hg19 (Hinxton)ENSG00000154813 [Gene_View]  chr3:16298568-16306496 [Contig_View]  DPH3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000154813 [Gene_View]  chr3:16298568-16306496 [Contig_View]  DPH3 [Vega]
ICGC DataPortalENSG00000154813
TCGA cBioPortalDPH3
AceView (NCBI)DPH3
Genatlas (Paris)DPH3
WikiGenes285381
SOURCE (Princeton)DPH3
Genetics Home Reference (NIH)DPH3
Genomic and cartography
GoldenPath hg19 (UCSC)DPH3  -     chr3:16298568-16306496 -  3p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DPH3  -     3p25.1   [Description]    (hg38-Dec_2013)
EnsemblDPH3 - 3p25.1 [CytoView hg19]  DPH3 - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBIDPH3 [Mapview hg19]  DPH3 [Mapview hg38]
OMIM608959   
Gene and transcription
Genbank (Entrez)AK022970 AK023203 AK092040 AK311618 BC010181
RefSeq transcript (Entrez)NM_001047434 NM_206831
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)DPH3
Cluster EST : UnigeneHs.388087 [ NCBI ]
CGAP (NCI)Hs.388087
Alternative Splicing GalleryENSG00000154813
Gene ExpressionDPH3 [ NCBI-GEO ]   DPH3 [ EBI - ARRAY_EXPRESS ]   DPH3 [ SEEK ]   DPH3 [ MEM ]
Gene Expression Viewer (FireBrowse)DPH3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285381
GTEX Portal (Tissue expression)DPH3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96FX2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96FX2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96FX2
Splice isoforms : SwissVarQ96FX2
PhosPhoSitePlusQ96FX2
Domaine pattern : Prosite (Expaxy)ZF_DPH (PS51074)   
Domains : Interpro (EBI)Znf_DHP   
Domain families : Pfam (Sanger)zf-CSL (PF05207)   
Domain families : Pfam (NCBI)pfam05207   
Conserved Domain (NCBI)DPH3
DMDM Disease mutations285381
Blocks (Seattle)DPH3
PDB (SRS)2JR7   
PDB (PDBSum)2JR7   
PDB (IMB)2JR7   
PDB (RSDB)2JR7   
Structural Biology KnowledgeBase2JR7   
SCOP (Structural Classification of Proteins)2JR7   
CATH (Classification of proteins structures)2JR7   
SuperfamilyQ96FX2
Human Protein AtlasENSG00000154813
Peptide AtlasQ96FX2
HPRD16412
IPIIPI00401015   IPI00514553   
Protein Interaction databases
DIP (DOE-UCLA)Q96FX2
IntAct (EBI)Q96FX2
FunCoupENSG00000154813
BioGRIDDPH3
STRING (EMBL)DPH3
ZODIACDPH3
Ontologies - Pathways
QuickGOQ96FX2
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  metal ion binding  negative regulation of protein secretion  positive regulation of binding  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  peptidyl-diphthamide biosynthetic process from peptidyl-histidine  metal ion binding  negative regulation of protein secretion  positive regulation of binding  
NDEx NetworkDPH3
Atlas of Cancer Signalling NetworkDPH3
Wikipedia pathwaysDPH3
Orthology - Evolution
OrthoDB285381
GeneTree (enSembl)ENSG00000154813
Phylogenetic Trees/Animal Genes : TreeFamDPH3
HOVERGENQ96FX2
HOGENOMQ96FX2
Homologs : HomoloGeneDPH3
Homology/Alignments : Family Browser (UCSC)DPH3
Gene fusions - Rearrangements
Fusion : MitelmanMAGI1/DPH3 [3p14.1/3p25.1]  [t(3;3)(p14;p25)]  
Fusion: TCGAMAGI1 3p14.1 DPH3 3p25.1 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPH3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPH3
dbVarDPH3
ClinVarDPH3
1000_GenomesDPH3 
Exome Variant ServerDPH3
ExAC (Exome Aggregation Consortium)DPH3 (select the gene name)
Genetic variants : HAPMAP285381
Genomic Variants (DGV)DPH3 [DGVbeta]
DECIPHER (Syndromes)3:16298568-16306496  ENSG00000154813
CONAN: Copy Number AnalysisDPH3 
Mutations
ICGC Data PortalDPH3 
TCGA Data PortalDPH3 
Broad Tumor PortalDPH3
OASIS PortalDPH3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPH3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPH3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPH3
DgiDB (Drug Gene Interaction Database)DPH3
DoCM (Curated mutations)DPH3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPH3 (select a term)
intoGenDPH3
Cancer3DDPH3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608959   
Orphanet
MedgenDPH3
Genetic Testing Registry DPH3
NextProtQ96FX2 [Medical]
TSGene285381
GENETestsDPH3
Huge Navigator DPH3 [HugePedia]
snp3D : Map Gene to Disease285381
BioCentury BCIQDPH3
ClinGenDPH3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285381
Chemical/Pharm GKB GenePA162384061
Clinical trialDPH3
Miscellaneous
canSAR (ICR)DPH3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPH3
EVEXDPH3
GoPubMedDPH3
iHOPDPH3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:46 CET 2017

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