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DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory)

Identity

Alias_namesdolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
Alias_symbol (synonym)MGC21559
MGC111193
Other aliasCDG1U
HGNC (Hugo) DPM2
LocusID (NCBI) 8818
Atlas_Id 62612
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 127935095 and ends at 127938484 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DPM2 (9q34.11) / PIP5KL1 (9q34.11)MIR548H2 (3q25.1) / DPM2 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPM2   3006
Cards
Entrez_Gene (NCBI)DPM2  8818  dolichyl-phosphate mannosyltransferase subunit 2, regulatory
AliasesCDG1U
GeneCards (Weizmann)DPM2
Ensembl hg19 (Hinxton)ENSG00000136908 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136908 [Gene_View]  chr9:127935095-127938484 [Contig_View]  DPM2 [Vega]
ICGC DataPortalENSG00000136908
TCGA cBioPortalDPM2
AceView (NCBI)DPM2
Genatlas (Paris)DPM2
WikiGenes8818
SOURCE (Princeton)DPM2
Genetics Home Reference (NIH)DPM2
Genomic and cartography
GoldenPath hg38 (UCSC)DPM2  -     chr9:127935095-127938484 -  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPM2  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblDPM2 - 9q34.11 [CytoView hg19]  DPM2 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBIDPM2 [Mapview hg19]  DPM2 [Mapview hg38]
OMIM603564   615042   
Gene and transcription
Genbank (Entrez)AB013361 AB451329 AB451473 AF061729 AI954002
RefSeq transcript (Entrez)NM_003863 NM_152690
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPM2
Cluster EST : UnigeneHs.108973 [ NCBI ]
CGAP (NCI)Hs.108973
Alternative Splicing GalleryENSG00000136908
Gene ExpressionDPM2 [ NCBI-GEO ]   DPM2 [ EBI - ARRAY_EXPRESS ]   DPM2 [ SEEK ]   DPM2 [ MEM ]
Gene Expression Viewer (FireBrowse)DPM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8818
GTEX Portal (Tissue expression)DPM2
Human Protein AtlasENSG00000136908-DPM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94777   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94777  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94777
Splice isoforms : SwissVarO94777
PhosPhoSitePlusO94777
Domains : Interpro (EBI)DPM2   
Domain families : Pfam (Sanger)DPM2 (PF07297)   
Domain families : Pfam (NCBI)pfam07297   
Conserved Domain (NCBI)DPM2
DMDM Disease mutations8818
Blocks (Seattle)DPM2
SuperfamilyO94777
Human Protein Atlas [tissue]ENSG00000136908-DPM2 [tissue]
Peptide AtlasO94777
HPRD16028
IPIIPI00179873   IPI00060112   IPI00513815   
Protein Interaction databases
DIP (DOE-UCLA)O94777
IntAct (EBI)O94777
FunCoupENSG00000136908
BioGRIDDPM2
STRING (EMBL)DPM2
ZODIACDPM2
Ontologies - Pathways
QuickGOO94777
Ontology : AmiGOglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  dolichyl-phosphate beta-D-mannosyltransferase activity  protein binding  endoplasmic reticulum membrane  GPI anchor biosynthetic process  preassembly of GPI anchor in ER membrane  protein N-linked glycosylation via asparagine  dolichol metabolic process  integral component of endoplasmic reticulum membrane  enzyme regulator activity  regulation of protein stability  dolichol-phosphate-mannose synthase complex  protein O-linked mannosylation  regulation of catalytic activity  
Ontology : EGO-EBIglycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex  dolichyl-phosphate beta-D-mannosyltransferase activity  protein binding  endoplasmic reticulum membrane  GPI anchor biosynthetic process  preassembly of GPI anchor in ER membrane  protein N-linked glycosylation via asparagine  dolichol metabolic process  integral component of endoplasmic reticulum membrane  enzyme regulator activity  regulation of protein stability  dolichol-phosphate-mannose synthase complex  protein O-linked mannosylation  regulation of catalytic activity  
Pathways : BIOCARTAErk1/Erk2 Mapk Signaling pathway [Genes]    Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway [Genes]    Trka Receptor Signaling Pathway [Genes]    Nerve growth factor pathway (NGF) [Genes]   
Pathways : KEGGN-Glycan biosynthesis    Glycosylphosphatidylinositol(GPI)-anchor biosynthesis   
NDEx NetworkDPM2
Atlas of Cancer Signalling NetworkDPM2
Wikipedia pathwaysDPM2
Orthology - Evolution
OrthoDB8818
GeneTree (enSembl)ENSG00000136908
Phylogenetic Trees/Animal Genes : TreeFamDPM2
HOVERGENO94777
HOGENOMO94777
Homologs : HomoloGeneDPM2
Homology/Alignments : Family Browser (UCSC)DPM2
Gene fusions - Rearrangements
Tumor Fusion PortalDPM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPM2
dbVarDPM2
ClinVarDPM2
1000_GenomesDPM2 
Exome Variant ServerDPM2
ExAC (Exome Aggregation Consortium)ENSG00000136908
GNOMAD BrowserENSG00000136908
Genetic variants : HAPMAP8818
Genomic Variants (DGV)DPM2 [DGVbeta]
DECIPHERDPM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPM2 
Mutations
ICGC Data PortalDPM2 
TCGA Data PortalDPM2 
Broad Tumor PortalDPM2
OASIS PortalDPM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch DPM2
DgiDB (Drug Gene Interaction Database)DPM2
DoCM (Curated mutations)DPM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPM2 (select a term)
intoGenDPM2
Cancer3DDPM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603564    615042   
Orphanet21904   
DisGeNETDPM2
MedgenDPM2
Genetic Testing Registry DPM2
NextProtO94777 [Medical]
TSGene8818
GENETestsDPM2
Target ValidationDPM2
Huge Navigator DPM2 [HugePedia]
snp3D : Map Gene to Disease8818
BioCentury BCIQDPM2
ClinGenDPM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8818
Chemical/Pharm GKB GenePA27464
Clinical trialDPM2
Miscellaneous
canSAR (ICR)DPM2 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPM2
EVEXDPM2
GoPubMedDPM2
iHOPDPM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Nov 20 19:26:52 CET 2017

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