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DPP10 (dipeptidyl peptidase like 10)

Identity

Alias_namesdipeptidylpeptidase 10
dipeptidyl-peptidase 10
dipeptidyl-peptidase 10 (inactive)
Alias_symbol (synonym)DPRP3
DPL2
DPPY
Other aliasDPRP-3
HGNC (Hugo) DPP10
LocusID (NCBI) 57628
Atlas_Id 62614
Location 2q14.1  [Link to chromosome band 2q14]
Location_base_pair Starts at 115162107 and ends at 115844750 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DAZAP2 (12q13.13) / DPP10 (2q14.1)DPP10 (2q14.1) / RAB10 (2p23.3)DPP10 (2q14.1) / RUNX1 (21q22.12)
DPP10 (2q14.1) / SPAST (2p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPP10   20823
Cards
Entrez_Gene (NCBI)DPP10  57628  dipeptidyl peptidase like 10
AliasesDPL2; DPPY; DPRP-3; DPRP3
GeneCards (Weizmann)DPP10
Ensembl hg19 (Hinxton)ENSG00000175497 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175497 [Gene_View]  chr2:115162107-115844750 [Contig_View]  DPP10 [Vega]
ICGC DataPortalENSG00000175497
TCGA cBioPortalDPP10
AceView (NCBI)DPP10
Genatlas (Paris)DPP10
WikiGenes57628
SOURCE (Princeton)DPP10
Genetics Home Reference (NIH)DPP10
Genomic and cartography
GoldenPath hg38 (UCSC)DPP10  -     chr2:115162107-115844750 +  2q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DPP10  -     2q14.1   [Description]    (hg19-Feb_2009)
EnsemblDPP10 - 2q14.1 [CytoView hg19]  DPP10 - 2q14.1 [CytoView hg38]
Mapping of homologs : NCBIDPP10 [Mapview hg19]  DPP10 [Mapview hg38]
OMIM608209   
Gene and transcription
Genbank (Entrez)AB040925 AK025075 AK055256 AK289967 AK296490
RefSeq transcript (Entrez)NM_001004360 NM_001178034 NM_001178036 NM_001178037 NM_001321905 NM_001321906 NM_001321907 NM_001321908 NM_001321909 NM_001321910 NM_001321911 NM_001321912 NM_001321913 NM_001321914 NM_020868
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DPP10
Cluster EST : UnigeneHs.657379 [ NCBI ]
CGAP (NCI)Hs.657379
Alternative Splicing GalleryENSG00000175497
Gene ExpressionDPP10 [ NCBI-GEO ]   DPP10 [ EBI - ARRAY_EXPRESS ]   DPP10 [ SEEK ]   DPP10 [ MEM ]
Gene Expression Viewer (FireBrowse)DPP10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57628
GTEX Portal (Tissue expression)DPP10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N608   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N608  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N608
Splice isoforms : SwissVarQ8N608
PhosPhoSitePlusQ8N608
Domains : Interpro (EBI)AB_hydrolase    Peptidase_S9    Peptidase_S9B_N   
Domain families : Pfam (Sanger)DPPIV_N (PF00930)    Peptidase_S9 (PF00326)   
Domain families : Pfam (NCBI)pfam00930    pfam00326   
Conserved Domain (NCBI)DPP10
DMDM Disease mutations57628
Blocks (Seattle)DPP10
PDB (SRS)4WJL   
PDB (PDBSum)4WJL   
PDB (IMB)4WJL   
PDB (RSDB)4WJL   
Structural Biology KnowledgeBase4WJL   
SCOP (Structural Classification of Proteins)4WJL   
CATH (Classification of proteins structures)4WJL   
SuperfamilyQ8N608
Human Protein AtlasENSG00000175497
Peptide AtlasQ8N608
HPRD07083
IPIIPI00873846   IPI00917254   IPI00916660   IPI00917666   IPI00916097   IPI00166892   IPI00915928   IPI00965616   
Protein Interaction databases
DIP (DOE-UCLA)Q8N608
IntAct (EBI)Q8N608
FunCoupENSG00000175497
BioGRIDDPP10
STRING (EMBL)DPP10
ZODIACDPP10
Ontologies - Pathways
QuickGOQ8N608
Ontology : AmiGOplasma membrane  proteolysis  serine-type peptidase activity  dipeptidyl-peptidase activity  potassium channel regulator activity  membrane  integral component of membrane  regulation of molecular function  protein localization to plasma membrane  positive regulation of establishment of protein localization to plasma membrane  regulation of potassium ion transmembrane transport  
Ontology : EGO-EBIplasma membrane  proteolysis  serine-type peptidase activity  dipeptidyl-peptidase activity  potassium channel regulator activity  membrane  integral component of membrane  regulation of molecular function  protein localization to plasma membrane  positive regulation of establishment of protein localization to plasma membrane  regulation of potassium ion transmembrane transport  
NDEx NetworkDPP10
Atlas of Cancer Signalling NetworkDPP10
Wikipedia pathwaysDPP10
Orthology - Evolution
OrthoDB57628
GeneTree (enSembl)ENSG00000175497
Phylogenetic Trees/Animal Genes : TreeFamDPP10
HOVERGENQ8N608
HOGENOMQ8N608
Homologs : HomoloGeneDPP10
Homology/Alignments : Family Browser (UCSC)DPP10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPP10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPP10
dbVarDPP10
ClinVarDPP10
1000_GenomesDPP10 
Exome Variant ServerDPP10
ExAC (Exome Aggregation Consortium)DPP10 (select the gene name)
Genetic variants : HAPMAP57628
Genomic Variants (DGV)DPP10 [DGVbeta]
DECIPHERDPP10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDPP10 
Mutations
ICGC Data PortalDPP10 
TCGA Data PortalDPP10 
Broad Tumor PortalDPP10
OASIS PortalDPP10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPP10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPP10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPP10
DgiDB (Drug Gene Interaction Database)DPP10
DoCM (Curated mutations)DPP10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPP10 (select a term)
intoGenDPP10
Cancer3DDPP10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608209   
Orphanet
MedgenDPP10
Genetic Testing Registry DPP10
NextProtQ8N608 [Medical]
TSGene57628
GENETestsDPP10
Target ValidationDPP10
Huge Navigator DPP10 [HugePedia]
snp3D : Map Gene to Disease57628
BioCentury BCIQDPP10
ClinGenDPP10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57628
Chemical/Pharm GKB GenePA134991647
Clinical trialDPP10
Miscellaneous
canSAR (ICR)DPP10 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPP10
EVEXDPP10
GoPubMedDPP10
iHOPDPP10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:36 CEST 2017

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