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DPP8 (dipeptidyl peptidase 8)

Identity

Alias_namesdipeptidylpeptidase 8
dipeptidyl-peptidase 8
Alias_symbol (synonym)DP8
DPRP1
MSTP141
FLJ14920
FLJ20283
MGC26191
Other aliasDPRP-1
MST097
MSTP097
MSTP135
HGNC (Hugo) DPP8
LocusID (NCBI) 54878
Atlas_Id 52087
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 65737998 and ends at 65810035 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPP8 (15q22.31) / DPP8 (15q22.31)DPP8 (15q22.31) / HACD3 (15q22.31)DPP8 (15q22.31) / MEGF11 (15q22.31)
DPP8 (15q22.31) / MOGAT2 (11q13.5)DPP8 (15q22.31) / TICRR (15q26.1)DPP8 15q22.31 C15orf42

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPP8   16490
Cards
Entrez_Gene (NCBI)DPP8  54878  dipeptidyl peptidase 8
AliasesDP8; DPRP-1; DPRP1; MST097; 
MSTP097; MSTP135; MSTP141
GeneCards (Weizmann)DPP8
Ensembl hg19 (Hinxton)ENSG00000074603 [Gene_View]  chr15:65737998-65810035 [Contig_View]  DPP8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000074603 [Gene_View]  chr15:65737998-65810035 [Contig_View]  DPP8 [Vega]
ICGC DataPortalENSG00000074603
TCGA cBioPortalDPP8
AceView (NCBI)DPP8
Genatlas (Paris)DPP8
WikiGenes54878
SOURCE (Princeton)DPP8
Genetics Home Reference (NIH)DPP8
Genomic and cartography
GoldenPath hg19 (UCSC)DPP8  -     chr15:65737998-65810035 -  15q22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DPP8  -     15q22.31   [Description]    (hg38-Dec_2013)
EnsemblDPP8 - 15q22.31 [CytoView hg19]  DPP8 - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBIDPP8 [Mapview hg19]  DPP8 [Mapview hg38]
OMIM606819   
Gene and transcription
Genbank (Entrez)AF173382 AF175225 AF176779 AF221634 AF221635
RefSeq transcript (Entrez)NM_001320875 NM_001320876 NM_017743 NM_130434 NM_197960 NM_197961
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)DPP8
Cluster EST : UnigeneHs.591106 [ NCBI ]
CGAP (NCI)Hs.591106
Alternative Splicing GalleryENSG00000074603
Gene ExpressionDPP8 [ NCBI-GEO ]   DPP8 [ EBI - ARRAY_EXPRESS ]   DPP8 [ SEEK ]   DPP8 [ MEM ]
Gene Expression Viewer (FireBrowse)DPP8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54878
GTEX Portal (Tissue expression)DPP8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6V1X1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6V1X1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6V1X1
Splice isoforms : SwissVarQ6V1X1
Catalytic activity : Enzyme3.4.14.5 [ Enzyme-Expasy ]   3.4.14.53.4.14.5 [ IntEnz-EBI ]   3.4.14.5 [ BRENDA ]   3.4.14.5 [ KEGG ]   
PhosPhoSitePlusQ6V1X1
Domains : Interpro (EBI)AB_hydrolase    Peptidase_S9    Peptidase_S9B_N   
Domain families : Pfam (Sanger)DPPIV_N (PF00930)    Peptidase_S9 (PF00326)   
Domain families : Pfam (NCBI)pfam00930    pfam00326   
Conserved Domain (NCBI)DPP8
DMDM Disease mutations54878
Blocks (Seattle)DPP8
SuperfamilyQ6V1X1
Human Protein AtlasENSG00000074603
Peptide AtlasQ6V1X1
HPRD07076
IPIIPI00377128   IPI00377129   IPI00412277   IPI00084071   IPI00026036   IPI00307553   IPI01009225   IPI00953307   
Protein Interaction databases
DIP (DOE-UCLA)Q6V1X1
IntAct (EBI)Q6V1X1
FunCoupENSG00000074603
BioGRIDDPP8
STRING (EMBL)DPP8
ZODIACDPP8
Ontologies - Pathways
QuickGOQ6V1X1
Ontology : AmiGOnucleoplasm  cytoplasm  cytoplasm  proteolysis  immune response  serine-type peptidase activity  dipeptidyl-peptidase activity  
Ontology : EGO-EBInucleoplasm  cytoplasm  cytoplasm  proteolysis  immune response  serine-type peptidase activity  dipeptidyl-peptidase activity  
NDEx NetworkDPP8
Atlas of Cancer Signalling NetworkDPP8
Wikipedia pathwaysDPP8
Orthology - Evolution
OrthoDB54878
GeneTree (enSembl)ENSG00000074603
Phylogenetic Trees/Animal Genes : TreeFamDPP8
HOVERGENQ6V1X1
HOGENOMQ6V1X1
Homologs : HomoloGeneDPP8
Homology/Alignments : Family Browser (UCSC)DPP8
Gene fusions - Rearrangements
Fusion : MitelmanDPP8/TICRR [15q22.31/15q26.1]  
Fusion: TCGADPP8 15q22.31 C15orf42 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPP8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPP8
dbVarDPP8
ClinVarDPP8
1000_GenomesDPP8 
Exome Variant ServerDPP8
ExAC (Exome Aggregation Consortium)DPP8 (select the gene name)
Genetic variants : HAPMAP54878
Genomic Variants (DGV)DPP8 [DGVbeta]
DECIPHER (Syndromes)15:65737998-65810035  ENSG00000074603
CONAN: Copy Number AnalysisDPP8 
Mutations
ICGC Data PortalDPP8 
TCGA Data PortalDPP8 
Broad Tumor PortalDPP8
OASIS PortalDPP8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPP8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPP8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPP8
DgiDB (Drug Gene Interaction Database)DPP8
DoCM (Curated mutations)DPP8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPP8 (select a term)
intoGenDPP8
Cancer3DDPP8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606819   
Orphanet
MedgenDPP8
Genetic Testing Registry DPP8
NextProtQ6V1X1 [Medical]
TSGene54878
GENETestsDPP8
Huge Navigator DPP8 [HugePedia]
snp3D : Map Gene to Disease54878
BioCentury BCIQDPP8
ClinGenDPP8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54878
Chemical/Pharm GKB GenePA27470
Clinical trialDPP8
Miscellaneous
canSAR (ICR)DPP8 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPP8
EVEXDPP8
GoPubMedDPP8
iHOPDPP8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:59:19 CEST 2017

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