DPPA3 (developmental pluripotency associated 3)

2007-04-01  

Identity

HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
Pgc7,STELLA

Other Information

Locus ID:

NCBI: 359787
MIM: 608408
HGNC: 19199
Ensembl: ENSG00000187569

Variants:

dbSNP: 359787
ClinVar: 359787
TCGA: ENSG00000187569
COSMIC: DPPA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187569ENST00000345088Q6W0C5

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
276814172016Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes.30
119009802002Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells.0
146540022003Stella is a maternal effect gene required for normal early development in mice.0
150186522004Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.0
162917412006Adult tissue-specific expression of a Dppa3-derived retrogene represents a postnatal transcript of pluripotent cell origin.0
171432672007PGC7/Stella protects against DNA demethylation in early embryogenesis.0
234576362013STELLA facilitates differentiation of germ cell and endodermal lineages of human embryonic stem cells.0
252809942014Inhibition of maintenance DNA methylation by Stella.0
266080312015Global DNA hypomethylation coupled to cellular transformation and metastatic ability.0
277944802016Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2.0

Citation

Dessen P

DPPA3 (developmental pluripotency associated 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47240/dppa3